scholarly journals Prevalence of potential drug- drug interactions and associated factors among outpatients and inpatients in Ethiopian Hospitals: a systematic review and Meta-analysis of observational studies

2020 ◽  
Author(s):  
Wondim Ayenew ◽  
Getahun Asmamaw ◽  
Arebu Issa
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Drug Interactions ◽  
Health Care System ◽  
Associated Factors ◽  
Meta Analysis ◽  
Potential Drug ◽  
Comorbid Disease ◽  
Factors Associated ◽  
Care System

Abstract Background A very few number of studies are available regarding the evaluation of potential drug- drug interactions in Sub-Saharan Africa. This is also a problem in Ethiopian health care system. Now a days, in Ethiopia polypharmacy is increased due to comorbid conditions in the hospital health care system, a large number of patients are treated in the outpatient setting and also hospitalized and there is a high possibility for drug- drug interactions. Therefore, this study aims to summarize the prevalence of potential drug- drug interactions and associated factors in hospitals, both among hospitalized patients and outpatients in Ethiopia.Method Literature search was performed through accessing legitimate databases in PubMed/MEDLINE, Google Scholar and Research Gate for English-language publications. Advanced search strategies were applied in Science Direct and HINARI to identify any additional papers and published reviews and to retrieve relevant findings closely related to prevalence of potential drug- drug interactions and associated factors with it. The search was conducted from August 22-25, 2019 and all published and unpublished articles available online until the day of data collection were considered.Results A total of 14 studies were included for systematic review and meta-analysis. From 14 studies, 5761 patients were included and a total of 8717 potential drug- drug interactions were found in 3259 of patients. The prevalence patients with potential drug- drug interactions in Ethiopian Hospitals were found to be 72.2% (95% confidence interval: 59.1%, 85.3%). Based on severity, the prevalence of potential drug- drug interactions were 25.1%, 52.8%, 16.9% and 1.27% for major, moderate, minor potential drug- drug interactions and contraindications respectively. The factors associated with potential drug- drug interactions were related to patient characteristics such as polypharmacy, age, comorbid disease and hospital stay.Conclusion There is a high prevalence of potential drug- drug interactions in Ethiopian Hospitals. From this the most prevalent drug- drug interactions were moderate severity, 52.8%. Polypharmacy, age, comorbid disease and hospital stay were the risk factors associated with potential drug- drug interactions.

scholarly journals Prevalence of potential drug- drug interactions and associated factors among outpatients and inpatients in Ethiopian Hospitals: a systematic review and Meta-analysis of observational studies

2020 ◽  
Author(s):  
Wondim Ayenew ◽  
Getahun Asmamaw ◽  
Arebu Issa
Keyword(s):  
Systematic Review ◽  
Drug Interactions ◽  
Hospital Stay ◽  
Associated Factors ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Potential Drug ◽  
Comorbid Disease ◽  
Factors Associated

Abstract Background: Drug-drug interaction is an emerging threat to the public health. In Ethiopia, there is high possibility of occurrence of drug-drug interactions in the hospitals. This is because of increased comorbid disease, increased polypharmacy, and increased hospitalization. Therefore, this study aims to summarize the prevalence of potential drug-drug interactions and associated factors in Ethiopian hospitals. Methods: Literature search was performed through accessing legitimate databases in PubMed/MEDLINE, Google Scholar and Research Gate for English-language publications. Advanced search strategies were applied in Science Direct and HINARI to identify any additional papers and published reviews and to retrieve relevant findings closely related to prevalence of potential drug- drug interactions and associated factors with it. The search was conducted from August 3-25, 2019 and all published articles available online until the day of data collection were considered. The pooled estimate of the outcome measure were analyzed by Open Meta Analyst advanced software. By considering clinical heterogeneity among original studies, Der Simonian and Laird’s random effect model were used. I2 statistics were used to assess heterogeneity among each studies. The publication bias was assessed by CMA version-3 software and presented with funnel plot of standard error and precision with Logit event rate. Results: A total of 14 studies were included for systematic review and meta-analysis. From 14 studies, 5761 patients were included and a total of 8717 potential drug- drug interactions were found in 3259 of patients. The prevalence patients with potential drug- drug interactions in Ethiopian Hospitals were found to be 72.2% (95% confidence interval: 59.1%, 85.3%). Based on severity, the prevalence of potential drug- drug interactions were 25.1%, 52.8%, 16.9% and 1.27% for major, moderate, minor potential drug- drug interactions and contraindications respectively. The factors associated with potential drug- drug interactions were related to patient characteristics such as polypharmacy, age, comorbid disease and hospital stay. Conclusions: There is a high prevalence of potential drug- drug interactions in Ethiopian Hospitals. Polypharmacy, age, comorbid disease and hospital stay were the risk factors associated with potential drug- drug interactions.

scholarly journals Prevalence of potential drug- drug interactions and associated factors among outpatients and inpatients in Ethiopian Hospitals: a systematic review and Meta-analysis of observational studies

2020 ◽  
Author(s):  
Wondim Ayenew ◽  
Getahun Asmamaw ◽  
Arebu Issa
Keyword(s):  
Systematic Review ◽  
Drug Interaction ◽  
Drug Interactions ◽  
Associated Factors ◽  
Meta Analysis ◽  
Random Effect Model ◽  
Potential Drug ◽  
Comorbid Disease ◽  
Factors Associated ◽  
Drug Drug Interaction

Abstract Background: Drug-drug interaction is an emerging threat to public health. Currently, there is an increase in comorbid disease, polypharmacy, and hospitalization in Ethiopia. Thus, the possibility of drug-drug interaction occurrence is high in hospitals. This study aims to summarize the prevalence of potential drug-drug interactions and associated factors in Ethiopian hospitals.Methods: A literature search was performed by accessing legitimate databases in PubMed/MEDLINE, Google Scholar, and Research Gate for English-language publications. To fetch further related topics advanced search was also applied in Science Direct and HINARI databases. The search was conducted on August 3 to 25, 2019. All published articles available online until the day of data collection were considered. Outcome measures were analyzed with Open Meta Analyst and CMA version statistical software. Der Simonian and Laird’s random effect model, I2 statistics, and Logit event rate were also performed.Results: A total of 14 studies remained eligible for inclusion in systematic review and meta-analysis. From the included studies, around 8,717 potential drug-drug interactions were found in 3,259 peoples out of 5,761 patients. The prevalence of patients with potential drug-drug interactions in Ethiopian hospitals was found to be 72.2% (95% confidence interval: 59.1%, 85.3%). Based on severity, the prevalence of major, moderate, and minor potential drug-drug interaction was 25.1%, 52.8%, 16.9%, respectively, also 1.27% for contraindications. The factors associated with potential drug-drug interactions were related to patient characteristics such as polypharmacy, age, comorbid disease, and hospital stay.Conclusions: There is a high prevalence of potential drug-drug interactions in Ethiopian hospitals. Polypharmacy, age, comorbid disease, and hospital stay were the risk factors associated with potential drug-drug interactions.

scholarly journals Prevalence of potential drug- drug interactions and associated factors among outpatients and inpatients in Ethiopian Hospitals: a systematic review and Meta-analysis of observational studies

2020 ◽  
Author(s):  
Wondim Ayenew ◽  
Getahun Asmamaw ◽  
Arebu Issa
Keyword(s):  
Systematic Review ◽  
Drug Interactions ◽  
Hospital Stay ◽  
Associated Factors ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Potential Drug ◽  
Comorbid Disease ◽  
Factors Associated

Abstract Background: Drug-drug interaction is an emerging threat to the public health. In Ethiopia, there is high possibility of occurrence of drug-drug interactions in the hospitals. This is because of increased comorbid disease, increased polypharmacy, and increased hospitalization. Therefore, this study aims to summarize the prevalence of potential drug-drug interactions and associated factors in Ethiopian hospitals. Methods: Literature search was performed through accessing legitimate databases in PubMed/MEDLINE, Google Scholar and Research Gate for English-language publications. Advanced search strategies were applied in Science Direct and HINARI to identify any additional papers and published reviews and to retrieve relevant findings closely related to prevalence of potential drug- drug interactions and associated factors with it. The search was conducted from August 3-25, 2019 and all published articles available online until the day of data collection were considered. The pooled estimate of the outcome measure were analyzed by Open Meta Analyst advanced software. By considering clinical heterogeneity among original studies, Der Simonian and Laird’s random effect model were used. I2 statistics were used to assess heterogeneity among each studies. The publication bias was assessed by CMA version-3 software and presented with funnel plot of standard error and precision with Logit event rate. Results: A total of 14 studies were included for systematic review and meta-analysis. From 14 studies, 5761 patients were included and a total of 8717 potential drug- drug interactions were found in 3259 of patients. The prevalence patients with potential drug- drug interactions in Ethiopian Hospitals were found to be 72.2% (95% confidence interval: 59.1%, 85.3%). Based on severity, the prevalence of potential drug- drug interactions were 25.1%, 52.8%, 16.9% and 1.27% for major, moderate, minor potential drug- drug interactions and contraindications respectively. The factors associated with potential drug- drug interactions were related to patient characteristics such as polypharmacy, age, comorbid disease and hospital stay. Conclusions: There is a high prevalence of potential drug- drug interactions in Ethiopian Hospitals. Polypharmacy, age, comorbid disease and hospital stay were the risk factors associated with potential drug- drug interactions.

scholarly journals Out-of-pocket and informal payments in Iran's health care system: A systematic review and meta-analysis

2017 ◽  
Vol 31 (1) ◽  
pp. 401-409 ◽  
Author(s):  
Seyed Abbas Mirabedini ◽  
Seyed Mohammad Esmaeil Fazl Hashemi ◽  
Ali Sarabi Asiabar ◽  
Aziz Rezapour ◽  
Saber Azami-Aghdash ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Health Care System ◽  
Meta Analysis ◽  
Informal Payments ◽  
System A ◽  
Care System

scholarly journals Survey the Situation of Perceived Organizational Justice in the Iranian Health Care System; A systematic review and meta-analysis

2021 ◽  
Author(s):  
Milad Shafiei ◽  
Najmeh Baghian ◽  
Amin Salehi ◽  
Mohammad Ranjbar ◽  
Maryam Hajipour
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Organizational Justice ◽  
Healthcare System ◽  
Health Care System ◽  
Meta Analysis ◽  
Public Hospitals ◽  
System A ◽  
The Status ◽  
Care System

Background: Perceived organizational justice is a concept used to describe job-related justice. Considering the role of perceived organizational justice in the healthcare system to increase the satisfaction, motivation, and efficiency in providing quality services, this study was conducted to investigate the situation of perceived organizational justice in the Iranian healthcare system through systematic review. Methods: In the present study, an electronic search was conducted on the Persian websites SID, Iranmedex,  Medlib, civilica, Irandoc and English Web of science, Pubmed, Scopus, and Google scholar using the Persian and English keywords of ‘Justice, Equality, Equality, Organizational Justice, Perceived Justice, Health System, University of Medical Sciences, Health Centers, Hospitals. As a result, 520 articles were studied and evaluated step by step and 469 papers were removed after reading the title and abstract. Finally, the full text of 51 articles was reviewed. Finally, 30 articles that measured the average level of perceived organizational justice were selected and other articles were excluded due to lack of necessary criteria and irrelevance. To analyze the heterogeneity between the studies, the meta-analysis method was used using Stata 14 software and Q test and I2 index. Results:  To study the status of perceived organizational justice in the health care system in a systematic and meta-analysis, all 30 studies were illegible. With regard to the dimensions of distributive, procedural, and interactive justice, 23 studies of 30 studies had the required conditions to enter the research.  The total mean score of perceived organizational justice was obtained as 60.71 and the mean scores of 54.74, 58.52, and 62.41were calculated for dimensions of distributive, procedural, and interactive justice, respectively. Conclusion: The findings showed that the situation of perceived organizational justice in the Iranian health care system was favorable. The dimension of interactive justice, related to managers' behaviors and relationships with employees, was relatively more favorable than other dimensions of organizational justice. Moreover, the situation of perceived organizational justice and its dimensions in private hospitals was more favorable than other research environments, including public hospitals, staff units, and hospitals selected using the mixed method.

Factors Associated With Americans' Ratings of Health Care Quality: What Do They Tell Us About the Raters and the Health Care System?

2010 ◽  
Vol 15 (sup3) ◽  
pp. 147-156 ◽  
Author(s):  
Wen-Ying Sylvia Chou ◽  
Lin Chun Wang ◽  
Lila J. Finney Rutten ◽  
Richard P. Moser ◽  
Bradford W. Hesse
Keyword(s):  
Health Care ◽  
Health Care System ◽  
Health Care Quality ◽  
Care Quality ◽  
Factors Associated ◽  
Care System

Factors Associated with Potential Drug–Drug Interactions in Patients Attended in Primary Health Care: A Focus on Mental Health

2017 ◽  
Vol 38 (9) ◽  
pp. 769-774 ◽  
Author(s):  
Tatiana Longo Borges ◽  
Kelly Graziani Giacchero Vedana ◽  
Ellen Carolina Dias Castilho ◽  
Adriana Inocenti Miasso
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Primary Health Care ◽  
Drug Interactions ◽  
Potential Drug ◽  
Factors Associated ◽  
Primary Health

Evaluation of Potential Drug–Drug Interactions in Adults in the Intensive Care Unit: A Systematic Review and Meta-Analysis

Drug Safety ◽  
2019 ◽  
Vol 42 (9) ◽  
pp. 1035-1044 ◽  
Author(s):  
Mary Grace Fitzmaurice ◽  
Adrian Wong ◽  
Hannah Akerberg ◽  
Simona Avramovska ◽  
Pamela L. Smithburger ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Drug Interactions ◽  
Meta Analysis ◽  
Potential Drug

CHARACTERISTICS OF MINDFULNESS BASED INTERVENTIONS FOR DIFFERENT PATIENT GROUPS – LITERATURE REVIEW

2018 ◽  
Vol 7 ◽  
pp. 140-152
Author(s):  
Indra Majore-Dūšele ◽  
Inese Paiča ◽  
Kristīne Mārtinsone ◽  
Inga Millere
Keyword(s):  
Health Care ◽  
Health Care System ◽  
Care Setting ◽  
Meta Analysis ◽  
Adult Population ◽  
Health Care Setting ◽  
Mindfulness Practice ◽  
Cochrane Library ◽  
Online Library ◽  
Care System

Mindfulness based interventions has been used in context with different mental and somatic health conditions in health care system with good evidences. In Latvia professionals working in psychiatry and rehabilitation are taking first steps to integrate mindfulness based interventions into their practice, therefore, guidelines for integration these interventions into the health care system is needed. The aim of this study is to evaluate existing evidences, content and mechanisms of mindfulness interventions for different patient groups.Electronic searches in PubMed, ProQuest, ScienceDirect, ClinicalKey, Cochrane Library, Wiley Online Library, and PsycInfo (2010 – 2018). Papers were required to meet the following criteria to be included in this review: (i) systematic review or meta-analysis; (ii) include quantitative outcomes for adult population in health care setting; (iii) published in English.Despite the good evidences, mindfulness based interventions are viewed as "complex intervention", researchers call for methodological, cultural and ethical attention to be made of implementing mindfulness practice into health care setting.

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