Validation of the REM sleep behavior disorder screening questionnaire in the Czech population

Abstract Background: Idiopathic rapid eye movement sleep behavior disorder (iRBD) affects 1 – 2% of people over 60 years of age and presents a high risk of developing a neurodegenerative disorder from the group of synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy. Therefore, screening tools are needed. In 2007, the rapid eye movement sleep behavior disorder screening questionnaire (RBD-SQ) was developed and has been translated into several languages. The aim of study was to assess the validity and reliability of the Czech version of the RBD-SQ in a mixed population of sleep clinic patients, supplemented by healthy volunteers and RBD patients. Methods: Participants included 81 iRBD patients, 205 patients with other sleep disorders (obstructive sleep apnea, insomnia, restless legs syndrome and periodic limb movement disorder, other parasomnias, or central hypersomnias including narcolepsy) and 20 healthy volunteers. ¨ Results: The mean RBD-SQ score in the iRBD patients was 9.4 ± 2.8 points, and in the non-RBD group it was 4.5 ± 3.0 (P < 0.0001). Receiver -operator analysis yielded an area under the curve of 0.864, suggesting good diagnostic performance of the scale. When using a cut-off value for positivity of 5 points, sensitivity was 0.89 and specificity was 0.62. Conclusions: The Czech version of the RBD-SQ is a sensitive tool for screening for iRBD patients and helps to identify subjects for complete clinical workup.

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Validation of the REM sleep behavior disorder screening questionnaire in the Czech population

10.21203/rs.2.444/v1 ◽

2019 ◽

Author(s):

Jitka Bušková ◽

Pavla Peřinová ◽

Eva Miletínová ◽

Petr Dušek ◽

Evžen Růžička ◽

...

Keyword(s):

Healthy Volunteers ◽

Neurodegenerative Disorder ◽

Rem Sleep Behavior Disorder ◽

Behavior Disorder ◽

Screening Tools ◽

Validity And Reliability ◽

Periodic Limb Movement Disorder ◽

Sleep Behavior ◽

Screening Questionnaire ◽

Obstructive Sleep

Abstract Background Idiopathic rapid eye movement sleep behavior disorder (RBD) affects 1 – 2% of people over 60 years of age, and presents a high risk of developing a neurodegenerative disorder from the group of synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy. Therefore, screening tools are needed. In 2007, the RBD screening questionnaire (RBD-SQ) was developed and has been translated into several languages. Aim of the study: The aim of study was to assess the validity and reliability of the Czech version of the RBD-SQ in a mixed population of sleep clinic patients, supplemented by healthy volunteers and RBD patients. Methods Participants included 81 RBD patients, 225 patients with other sleep disorders (obstructive sleep apnea, insomnia, restless legs syndrome and periodic limb movement disorder, other parasomnias, or central hypersomnias including narcolepsy) and 20 healthy volunteers. Results The mean RBD-SQ score in the RBD patients was 9.4 ± 2.8 points, and in the non-RBD group it was 4.5 ± 3.0 (P < 0.0001). Receiver -operator analysis yielded an area under the curve of 0.864, suggesting good diagnostic performance of the scale. When using a cut-off value for positivity of 5 points, sensitivity was 0.89 and specificity was 0.62. Conclusions The Czech version of the RBD-SQ is a sensitive tool for screening for RBD patients and helps to identify subjects for complete clinical workup.

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Validation of the rapid eye movement sleep behavior disorder screening questionnaire in China

Journal of Clinical Neuroscience ◽

10.1016/j.jocn.2015.03.008 ◽

2015 ◽

Vol 22 (9) ◽

pp. 1420-1424 ◽

Cited By ~ 19

Author(s):

Yan Wang ◽

Zong-Wen Wang ◽

Yue-Chang Yang ◽

Hui-Juan Wu ◽

Hong-Yi Zhao ◽

...

Keyword(s):

Eye Movement ◽

Behavior Disorder ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Sleep Behavior ◽

Screening Questionnaire

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Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire--Brazilian Portuguese Version

PsycTESTS Dataset ◽

10.1037/t83079-000 ◽

2020 ◽

Author(s):

Márcio Alexandre Pena-Pereira ◽

Manoel Alves Sobreira-Neto ◽

Emmanuelle Sobreira ◽

Marcos Hortes Nisihara Chagas ◽

Daniel Sabino de Oliveira ◽

...

Keyword(s):

Eye Movement ◽

Behavior Disorder ◽

Brazilian Portuguese ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Sleep Behavior ◽

Screening Questionnaire ◽

Portuguese Version

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Probable rapid eye movement sleep behavior disorder, nocturnal disturbances and quality of life in patients with Parkinson’s disease: a case-controlled study using the rapid eye movement sleep behavior disorder screening questionnaire

BMC Neurology ◽

10.1186/1471-2377-13-18 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 19

Author(s):

Keisuke Suzuki ◽

Tomoyuki Miyamoto ◽

Masayuki Miyamoto ◽

Yuka Watanabe ◽

Shiho Suzuki ◽

...

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Eye Movement ◽

Behavior Disorder ◽

Controlled Study ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Sleep Behavior ◽

Screening Questionnaire

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Rapid Eye Movement Sleep Behavior Disorder-like Symptoms Due to Arousal Responses Associated with Severe Obstructive Sleep Apnea-hypopnea

Internal Medicine ◽

10.2169/internalmedicine.6218-20 ◽

2021 ◽

Author(s):

Kazushi Deguchi ◽

Tomokazu Doi ◽

Tadayuki Takata ◽

Yohei Kokudo ◽

Hideki Kobara ◽

...

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Eye Movement ◽

Behavior Disorder ◽

Severe Obstructive Sleep Apnea ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Sleep Behavior ◽

Obstructive Sleep

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Validation of the Turkish Version of the Rapid Eye Movement Sleep Behavior Disorder Questionnaire

Behavioural Neurology ◽

10.1155/2016/8341651 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Itır Tarı Cömert ◽

Zerrin Pelin ◽

Tolga Arıcak ◽

Saadet Yapan

Keyword(s):

Eye Movement ◽

Sleep Apnea Syndrome ◽

Behavior Disorder ◽

Healthy Controls ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Validity And Reliability ◽

Turkish Version ◽

Sleep Behavior ◽

Obstructive Sleep

The aim of this study was to assess the validity and reliability of a Turkish version of the rapid eye movement sleep behavior disorder questionnaire (the RBDSQ-T) for identifying patients with rapid eye movement sleep behavior disorder (RBD) and to ensure that this tool can be applied in Turkish language. Three groups were enrolled to validate the RBDSQ-T: 78 healthy controls, 17 patients previously diagnosed with RBD, and 28 patients with obstructive sleep apnea syndrome (OSAS). Based on a cut-off score of five, the RBDSQ-T was able to discriminate RBD patients from healthy controls with sensitivity of 100% and specificity of 87%. Accordingly, 63% of patients were correctly diagnosed using the RBDSQ-T. Similarly, with a cut-off score of five, the RBDSQ-T was able to discriminate RBD from OSAS with sensitivity of 100% and specificity of 64%. Assessment of test-retest reliability and internal consistency reliability using Kuder-Richardson 20 analysis revealed a test-retest correlation coefficient of 0.95 and a Kuder-Richardson 20 value of 0.82. The findings demonstrate that the RBDSQ-T is a valid and reliable tool.

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Actigraphic Screening for Rapid Eye Movement Sleep Behavior Disorder

10.1101/19001867 ◽

2019 ◽

Author(s):

Šandala Kristián ◽

Dostálová Simona ◽

Nepožitek Jiří ◽

Ibarburu Lorenzo y Losada Veronika ◽

Dušek Petr ◽

...

Keyword(s):

Motor Activity ◽

Eye Movement ◽

Neurodegenerative Disorder ◽

Behavior Disorder ◽

Sleep Fragmentation ◽

Dominant Hand ◽

Healthy Controls ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Sleep Behavior

AbstractBackgroundThe patients suffering of the rapid eye movement sleep behavior disorder (RBD) are in high risk of developing a neurodegenerative disorder, most frequently from the group of alpha-synucleinopathies, such as Parkinson’s disease (PD), Dementia with Lewy Bodies (DLB) or multiple system atrophy (MSA). The definitive diagnosis of RBD is based on polysomnographic investigation. Actigraphy is much easier to perform and reflects condition in patient’s home environment.The aimsThe aim of this study was to find suitable biomarkers for RBD, which can be detectable by actigraphic recording.MethodsHigh resolution actigraphic recording (MotionWatch, CamNtech ltd.) and confirming polysomnographic recording was performed on 45 RBD patients, 30 patients with other sleep-related motor disorders and 20 healthy controls. Each individual file was analysed by software testing for amount of sleep (MotionWare 1.1.20) and secondly for periodic motor activity (PLMS analysis 1.0.16). The 13-item patient self-rating RBD screening questionnaire (RBD-SQ) translated to Czech language was also used for screening purposes. We used an RBD-SQ score of five points as a positive test result, as suggested by the original publication of the scale.ResultsWhen using the actigraphic sleep detection, we encountered significant differences mostly on non-dominant hand, related to sleep fragmentation - most notably increased percentage of Short immobile bouts (47.0% vs. 28.0%, p<0.0001), increased Fragmentation index (72.5 vs. 40.7, p<0.0001) and decreased percentage of Sleep efficiency (72.1% vs. 86.8%, p<0.0001)in RBD subjects compared to other sleep disorders and controls. When analyzing periodic motor activity, we also found surprisingly more periodic hand movements (p=0.028, corrected for multiple testing), but differences on lower extremities using either measurement were not significant. The discrimination function based on RBD-SQ and Short immobile bouts % could allocate correctly the RBD status in 87.6% of cases with Wilks Lambda 0.435 and p<0.0001.ConclusionIn our single-center study in patients from the Czech population, we found that actigraphic recording from upper extremities shows consistently more prominent sleep fragmentation in RBD patients compared to other sleep diagnoses or healthy controls. Actigraphy may be useful in broader screening for RBD.

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Validation of the Brazilian Portuguese version of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ-BR)

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20200125 ◽

2020 ◽

Vol 78 (10) ◽

pp. 629-637 ◽

Cited By ~ 1

Author(s):

Márcio Alexandre PENA-PEREIRA ◽

Manoel Alves SOBREIRA-NETO ◽

Emmanuelle SOBREIRA ◽

Marcos Hortes Nisihara CHAGAS ◽

Daniel Sabino de OLIVEIRA ◽

...

Keyword(s):

Eye Movement ◽

Likelihood Ratio ◽

Behavior Disorder ◽

Brazilian Portuguese ◽

Rapid Eye Movement ◽

Rapid Eye Movement Sleep ◽

Convenience Sample ◽

Sleep Behavior ◽

Screening Questionnaire ◽

Portuguese Version

ABSTRACT Introduction: A diagnosis of rapid eye movement sleep behavior disorder (RBD) currently requires confirmation with polysomnography (PSG). However, PSG may not be sufficiently available. In these situations, a clinical diagnostic measure might be useful. Objective: To validate the Brazilian Portuguese version of RBD screening questionnaire (RBDSQ) for patients with Parkinson’s disease (PD). Methods: Using detailed clinical interviews and PSG analysis (diagnostic gold standard), a convenience sample of 69 subjects was divided into the following subgroups: patients with PD and RBD (PD+RBD; n=50) and patients with PD alone (PD-RBD; n=19). Results: RBDSQ-BR showed adequate internal consistency (Cronbach’s α=0.809) and, except for item 8, adequate item-test correlation. The retest performed in a second sample (n=13, consecutive) showed high agreement for total score (intraclass correlation coefficient, ICC=0.863) and acceptable agreement for items 2, 3, 6.2, 6.3, 7, and 8 (K>0.60). The receiver operating characteristic (ROC) curve analysis had an area under the curve (AUC) of 0.728. A cut-off score of 4 enabled the correct diagnosis of 76.8% subjects and provided the best balance between sensitivity (84%) and specificity (57.9%), with a 2.0 likelihood ratio of a positive result (LR+) and a 0.3 likelihood ratio of a negative result (LR-). Items 2 and 6.2 had 84.2% specificity and 3.2 LR+. Combined items 1+2+6.2, 2+6.1, and 6.1+6.2 increased the specificity to 94.7%, with LR+ ranging from 6.1 to 7.6. Conclusions: RBDSQ-BR is a reliable instrument, which may be useful for RBD diagnosis of Brazilian patients with PD. The instrument is also valid and may help in a better selection of cases for a more detailed clinical evaluation or even PSG analysis.

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