scholarly journals Clinical Profiles in Acute Heart Failure

2021 ◽  
Author(s):  
Susana García-Gutiérrez ◽  
Ane Antón-Ladislao ◽  
Raul Quiros ◽  
Antonio Lara ◽  
Irene Rilo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cluster Analysis ◽  
Acute Heart Failure ◽  
De Novo ◽  
Multiple Correspondence Analysis ◽  
Cardiovascular Comorbidity ◽  
Clinical Phenotypes ◽  
Patient Reported ◽  
Clinical Profiles ◽  
Group B

Abstract Background:Phenotypes could be more frequently related to outcomes than classical classifications of AHF. Our goal was to identify clinical profiles for acute heart failure (AHF) based on clinical variables at the time of the patient arrival to the Emergency Department (ED).Methods:Design: Prospective cohort study. Participants: Patients with symptoms of AHF were recruited at the EDs of seven Spanish National Health Service hospitals between April 2013 and December 2014. Main measures: Information on sociodemographic, baseline functional status, medical history, and time since diagnosis was collected when the patient arrived at the ED. In addition, the MLWHF questionnaire was administered at arrival and at 1 year after discharge from the ED. Change in MLWHF score and mortality, revisits and readmissions during this first year were considered as outcomes. We combined multiple correspondence analysis (MCA) and cluster analysis (CA) to create clinical profiles.Results:A total of 1599 subjects were included in the study. Patients were located on two axes: one was defined as duration of HF and the other as cardiovascular comorbidity. Cluster analysis identified three subtypes of patient (A, B, and C), group B being most frequently corresponding to a “de novo” case. Differences in outcome, including mortality, readmissions and changes in MLWHF score, were encountered between group B and the rest of the groups, results being similar in groups A and C.Conclusions:The clinical phenotypes found were associated with clinical and patient-reported outcomes. Such clinical phenotypes could be useful in decision making processes in ED settings.Clinical registration:ClinicalTrials.gov ID: NCT03512704

scholarly journals Distinct clinical phenotypes of congestion in acute heart failure: characteristics, treatment response, and outcomes

2020 ◽  
Vol 7 (6) ◽  
pp. 3830-3840
Author(s):  
Justyna Maria Sokolska ◽  
Mateusz Sokolski ◽  
Robert Zymliński ◽  
Jan Biegus ◽  
Paweł Siwołowski ◽  
...  
Keyword(s):  
Heart Failure ◽  
Treatment Response ◽  
Acute Heart Failure ◽  
Failure Characteristics ◽  
Clinical Phenotypes

scholarly journals Acute Heart Failure developed as worsening of Chronic Heart Failure is associated with increased mortality compared to de novo cases

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Vesna Degoricija ◽  
Matias Trbušić ◽  
Ines Potočnjak ◽  
Bojana Radulović ◽  
Sanda Dokoza Terešak ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Acute Heart Failure ◽  
De Novo

Abstract 17352: Differences in Clinical Characteristics, Risk Factors, Rate of Recurrence and 1-year Outcome Between Acute Heart Failure Patients With Stroke or TIA and Those Without This Co-morbidity. Results From the Gulf aCute heArt failuRe rEgistry (gulf Care)

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Mohammed A Al Hashemi ◽  
Kadhim Sulaiman ◽  
Jassim Al-Suwaidi ◽  
Khalid F AlHabib ◽  
Husam AlFaleh ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Clinical Characteristics ◽  
De Novo ◽  
Stroke Patients ◽  
Lv Dysfunction ◽  
Co Morbidity ◽  
History Of ◽  
One Year ◽  
Ischemic Attack

Background: Chronic heart failure (CHF) is a known risk for stroke and morbidities and mortalities are known to be higher in CHF patients compared to stroke patients without CHF we here study the prevalence and the clinical significance in a group of patient with stroke or transient ischemic attack (TIA) who were admitted to hospital with acute heart failure (AHF) compared to those without stroke and are admitted with acute heart failure Methods: Data were derived from a prospective, multicenter, multinational study of 5005 patients hospitalized with AHF from February 2013 to November 2012. Data were analyzed according to the presence or absence of Stroke or bronchial TIA. Demographic, management, in-hospital and 1-year outcomes were compared Results: Stroke patients were likely to have a decompensation of chronic failure rather than De-Novo AHF when compared to those without Stroke/TIA (see table). Stroke patients were older; more likely to be female, have history of DM, HTN, dyslipidemia and CKD. Stroke patients were likely to have Atrial fibrillation, PVD, systolic LV dysfunction as well as CAD when compared to those without Stroke, they were also more likely receive NIV, IV inotropes and likely to have had cardiac PCI prior to this admission with AHF. Stroke patients had higher recurrence of stroke and one-year mortality rates. Conclusion: Patients who presented with AHF and history of stroke/TIA were having different clinical characteristics as well as comorbidities as compared to those without Stroke, with worse in-hospital and one-year outcome. The current study underlies the need to aggressively manage these high-risk patients.

Female gender is associated with a worse prognosis amongst patients hospitalised for de‐novo acute heart failure

2020 ◽  
Author(s):  
Wesam Mulla ◽  
Robert Klempfner ◽  
Sharon Natanzon ◽  
Israel Mazin ◽  
Leonid Maizels ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
De Novo ◽  
Female Gender ◽  
Worse Prognosis

scholarly journals Clinical profiles and prognosis of acute heart failure in adult patients with dystrophinopathies on home mechanical ventilation

2017 ◽  
Vol 4 (4) ◽  
pp. 527-534 ◽  
Author(s):  
Abdallah Fayssoil ◽  
Rabah Ben Yaou ◽  
Adam Ogna ◽  
France Leturcq ◽  
Olivier Nardi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mechanical Ventilation ◽  
Acute Heart Failure ◽  
Adult Patients ◽  
Home Mechanical Ventilation ◽  
Clinical Profiles

Identifying novel phenotypes of acute heart failure using cluster analysis of clinical variables

2018 ◽  
Vol 262 ◽  
pp. 57-63 ◽  
Author(s):  
Yu Horiuchi ◽  
Shuzou Tanimoto ◽  
A.H.M. Mahbub Latif ◽  
Kevin Y. Urayama ◽  
Jiro Aoki ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cluster Analysis ◽  
Acute Heart Failure ◽  
Clinical Variables

Acute heart failure: early pharmacological therapy

2018 ◽  
Author(s):  
Jonathan R Dalzell ◽  
Colette E Jackson ◽  
Roy Gardner ◽  
John JV McMurray
Keyword(s):  
Heart Failure ◽  
Cardiogenic Shock ◽  
Acute Heart Failure ◽  
Mechanical Circulatory Support ◽  
De Novo ◽  
Treatment Approach ◽  
Pharmacological Therapy ◽  
Current Therapy ◽  
Circulatory Support ◽  
Clinical Presentations

Acute heart failure syndromes consist of a spectrum of clinical presentations due to an impairment of some aspect of the cardiac function. They represent a final common pathway for a vast array of pathologies and may be either a de novo presentation or, more commonly, a decompensation of pre-existing chronic heart failure. Despite being one of the most common medical presentations, there are no definitively proven prognosis-modifying treatments. The mainstay of current therapy is oxygen and intravenous diuretics. However, within this spectrum of presentations, there is a crucial dichotomy which governs the ultimate treatment approach, i.e. the presence, or absence, of cardiogenic shock. Patients without cardiogenic shock may receive vasodilators, whilst shocked patients should be considered for treatment with inotropic therapy or mechanical circulatory support, when appropriate and where available.

Sign in / Sign up

Export Citation Format

Share Document