scholarly journals Smaller Amygdala Subnuclei Volume in Schizophrenia Patients with Violent Behaviors

2022 ◽  
Author(s):  
Hao Hu ◽  
Fengju Liu ◽  
Li Liu ◽  
Yi Mei ◽  
Bin Xie ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Central Nucleus ◽  
Violence Risk ◽  
Healthy Controls ◽  
Resonance Imaging ◽  
Basal Nucleus ◽  
Violent Behaviors ◽  
Weighted Magnetic Resonance Imaging

Abstract Objective To investigate the association between the volume of amygdala subnuclei and violent behaviors in patients with schizophrenia (SCZ). Methods In the present study, we recruited 40 SCZ patients with violent behaviors (VS), 26 SCZ patients without violent behaviors (NVS), and 28 matched healthy controls (HC) who completed T1-weighted magnetic resonance imaging. Both the total amygdala and amygdala subnuclei volumes were estimated with FreeSurfer. Results When comparing the whole SCZ patients with HC, SCZ patients had smaller volume of the left amygdala and the left basal nucleus. Further, the VS patients had smaller volume of the amygdala central nucleus as compared to the NVS group. Conclusions Our findings suggested that a smaller volume of the amygdala central nucleus might be relevant to violence risk in SCZ patients.

scholarly journals Value of Abdominal Susceptibility-Weighted Magnetic Resonance Imaging for Quantitative Assessment of Hepatic Iron Deposition in Patients with Chronic Hepatitis B: Comparison with Serum Iron Markers

2012 ◽  
Vol 40 (3) ◽  
pp. 1005-1015 ◽  
Author(s):  
W Lv ◽  
F Yan ◽  
M Zeng ◽  
J Zhang ◽  
Y Yuan ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Chronic Hepatitis ◽  
Magnetic Resonance ◽  
Serum Iron ◽  
Hbv Infection ◽  
Iron Deposition ◽  
Hepatic Iron ◽  
Healthy Controls ◽  
Resonance Imaging ◽  
Weighted Magnetic Resonance Imaging

OBJECTIVE: To assess hepatic iron deposition quantitatively in patients with chronic hepatitis B (HBV) infection, using abdominal susceptibility-weighted magnetic resonance imaging (SWI). METHODS: Patients with HBV infection and healthy controls underwent abdominal SWI and were assessed for serum iron markers. Phase values were measured and five grades of hepatic iron deposition were described by SWI. RESULTS: Patients with HBV infection ( n = 327) and healthy controls ( n = 50) were prospectively enrolled. In total, 77 (25.4%) patients with HBV infection had hepatic iron deposition as determined by SWI. Phase values were significantly different between patients with hepatic iron deposition compared with patients without hepatic iron deposition or controls, and were significantly different across different grades of hepatic iron deposition. Serum iron, ferritin, transferrin and transferrin saturation were significantly higher in patients with, versus those without, hepatic iron deposition. Only serum ferritin was significantly different across different grades of hepatic iron deposition, and there was a low inverse correlation between serum ferritin and phase values. CONCLUSIONS: Compared with serum iron markers, abdominal SWI may represent a powerful tool to assess hepatic iron deposition quantitatively in patients with chronic HBV infection.

scholarly journals Assessment of lacrimal glands in thyroid eye disease with diffusion-weighted magnetic resonance imaging

2019 ◽  
Vol 84 ◽  
pp. 142-146 ◽  
Author(s):  
Ahmed Razek ◽  
El-hadidy Mohamed El-Hadidy ◽  
Mohamed El-Said Moawad ◽  
Nader El-Metwaly ◽  
Amr Abd El-hamid El-Said
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Resonance Imaging ◽  
Lacrimal Glands ◽  
Diffusion Weighted ◽  
Weighted Magnetic Resonance Imaging

Biomineralized iron oxide–polydopamine hybrid nanodots for contrast-enhanced T1-weighted magnetic resonance imaging and photothermal tumor ablation

2021 ◽  
Vol 9 (7) ◽  
pp. 1781-1786
Author(s):  
Ze’ai Wang ◽  
Yanfeng Wang ◽  
Yuan Wang ◽  
Chaogang Wei ◽  
Yibin Deng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Therapeutic Efficacy ◽  
Tumor Ablation ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Weighted Magnetic Resonance Imaging

Biomineralized iron oxide–polydopamine hybrid nanodots are constructed using albumin nanoreactors to facilitate contrast-enhanced T1-weighted magnetic resonance imaging as well as photothermal therapeutic efficacy.

scholarly journals Altered sense of agency in Gilles de la Tourette syndrome: behavioural, clinical and functional magnetic resonance imaging findings

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Laura Zapparoli ◽  
Silvia Seghezzi ◽  
Francantonio Devoto ◽  
Marika Mariano ◽  
Giuseppe Banfi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Tourette Syndrome ◽  
Sense Of Agency ◽  
Healthy Controls ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Intentional Binding ◽  
Action Monitoring

Abstract Current neurocognitive models of motor control postulate that accurate action monitoring is crucial for a normal experience of agency—the ability to attribute the authorship of our actions and their consequences to ourselves. Recent studies demonstrated that action monitoring is impaired in Gilles de la Tourette syndrome, a movement disorder characterized by motor and vocal tics. It follows that Tourette syndrome patients may suffer from a perturbed sense of agency, the hypothesis tested in this study. To this end, we recruited 25 Tourette syndrome patients and 25 matched healthy controls in a case-control behavioural and functional magnetic resonance imaging study. As an implicit index of the sense of agency, we measured the intentional binding phenomenon, i.e., the perceived temporal compression between voluntary movements and their external consequences. We found evidence of an impaired sense of agency in Tourette syndrome patients who, as a group, did not show a significant intentional binding. The more reduced was the individual intentional binding, the more severe were the motor symptoms. Specific differences between the two groups were also observed in terms of brain activation patterns. In the healthy controls group, the magnitude of the intentional binding was associated with the activity of a premotor–parietal–cerebellar network. This relationship was not present in the Tourette syndrome group, suggesting an altered activation of the agency brain network for self-generated acts. We conclude that the less accurate action monitoring described in Tourette syndrome also involves the assessment of the consequences of actions in the outside world. We discuss that this may lead to difficulties in distinguishing external consequences produced by their own actions from the ones caused by others in Tourette syndrome patients.

scholarly journals Multiple b values of diffusion-weighted magnetic resonance imaging in evaluation of solid head and neck masses

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Rania Sobhy Abou khadrah ◽  
Haytham Haroon Imam
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Head And Neck ◽  
Resonance Imaging ◽  
Adc Value ◽  
Neck Masses ◽  
Adc Values ◽  
Weighted Magnetic Resonance Imaging ◽  
The Mean ◽  
Head And Neck Masses

Abstract Background Differentiation between malignant and benign masses is essential for treatment planning and helps in improving the prognosis of malignant tumors; the aim of this work is to determine the role of diffusion-weighted magnetic resonance imaging (DW-MRI) and the apparent diffusion coefficient (ADC) in the differentiation between benign and malignant solid head and neck masses by comparing diagnostic performance of low b values (0.50 and 400 s/mm2) versus high b values (800 and 1000 s/mm2) and comparing the result with histopathological finding. Results The study included 60 patients (34 male and 26 female) with solid head and neck masses > 1 cm who referred to radiodiagnosis department for MRI evaluation. Multiple b values were used 50, 400, 800, and 1000 s/mm2 (at least 2 b values). DWI and ADC value of all 60 patients were acquired. Mean ADC values of both malignant and benign masses were statistically measured and compared, and cut off value was determined. Solid head and neck masses in our study DWI with the use of high b value 800 and 1000 s/mm2 were of higher significance (P value 0.001*). There was a significant difference in the mean ADC value between benign and malignant masses (P < 0.01); solid masses were divided into 2 categories: (a) malignant lesions 46.7% (n = 28) with mean ADC value (0.82 ± 0.19) × 10−3 s/mm2 and (b) benign lesions 53.3% (n = 32) with mean ADC value (2.05 ± 0.46) × 10−3 s/mm2) with ADC cutoff value of 1.0 × 10−3 s/mm2 and 94% sensitivity, 93% specificity, negative predictive value (NPV) = 94%, positive predictive value (PPV) 93%, and an accuracy of 93.5%. Conclusion The DWI with ADC mapping were valuable as non-invasive tools in differentiating between benign and malignant solid head and neck masses. The use of high b value 800 and 1000 s/mm2 was of higher significance (P value 0.001*) in differentiation between benign and malignant lesion than that with low b values 0, 50, and 400 s/mm2 (0.01). The mean ADC values were significantly lower in malignant solid masses. Attention had to be paid to the choice of b values in MRI-DWI in the head and neck region.

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