scholarly journals Changes levels of myokines after aerobic training and resistance training in post-menopausal females with obesity

2020 ◽  
Author(s):  
Sunghwun Kang ◽  
Il Bong Park ◽  
Seung-Taek Lim

Abstract Background To investigate changes in levels of myokines after regular aerobic training and resistance training in post- menopausal females with obesity. Methods Among 41 post- menopausal obese females volunteered to participate in this study performed regular physical exercise training (aerobic exercise and resistance exercise). These participants were randomly assigned to one aerobic exercise group (n = 21) and one resistance exercise group (n = 20). The experimental group performed three days of aerobic exercise and resistance exercise per week (i.e., Monday, Wednesday, and Friday) each group. Body composition, physical fitness, and myokines were measured at baseline, 6 weeks, and 12 weeks. Results Two-way within-factor ANOVA revealed group × time interaction for body mass index (BMI, p < 0.05). In the resistance exercise group, muscle endurance, power, and agility were significantly increased at 12 weeks than those at 6 weeks and baseline. In the aerobic exercise group, muscle strength, flexibility, muscle endurance, and agility were greater at 12 weeks than those at 6 weeks and baseline. Levels of IL-6, IL15, and BDNF were greater at 12 weeks than those at 6 weeks and baseline in both exercise groups. Conclusions Aerobic exercise training and resistance exercise training can change levels of myokines and improve body composition and physical fitness of obese females. These findings provide preliminary evidence that obese females need to exercise or perform physical activity to improve their levels of myokines and physical fitness.

2020 ◽  
Author(s):  
Sunghwun Kang ◽  
Il Bong Park ◽  
Seung-Taek Lim

Abstract Background To investigate changes in levels of myokines after regular aerobic training and resistance training in post- menopausal females with obesity. Methods A community-based a randomized controlled trial study was 41 post- menopausal females with obesity from Buk-gu community center, Chuncheon, Gangwon-do, Republic of Korea, from November 2017 until the end of October 2018. Among 41 post- menopausal obese females volunteered to participate in this study performed regular physical exercise training (aerobic exercise and resistance exercise). These participants were randomly assigned to one aerobic exercise group (n = 21) and one resistance exercise group (n = 20). The experimental group performed three days of aerobic exercise and resistance exercise per week (i.e., Monday, Wednesday, and Friday) each group. Body composition, physical fitness, and myokines were measured at baseline, 6 weeks, and 12 weeks. Results Two-way within-factor ANOVA revealed group × time interaction for body mass index (BMI, P < 0.05). In the resistance exercise group, muscle endurance (P < 0.001), power (P < 0.01), and agility (P < 0.001) were significantly increased at 12 weeks than those at 6 weeks and baseline. In the aerobic exercise group, muscle strength (P < 0.05), flexibility (P < 0.05), muscle endurance (P < 0.001), and agility (P < 0.001) were greater at 12 weeks than those at 6 weeks and baseline. Levels of IL-6 (P < 0.001), IL15 (P < 0.001), and BDNF (P < 0.001) were greater at 12 weeks than those at 6 weeks and baseline in both exercise groups. Conclusions Aerobic exercise training and resistance exercise training can change levels of myokines and improve body composition and physical fitness of obese females. These findings provide preliminary evidence that obese females need to exercise or perform physical activity to improve their levels of myokines and physical fitness.


2020 ◽  
Vol 12 (20) ◽  
pp. 8413
Author(s):  
Sunghwun Kang ◽  
Il Bong Park ◽  
Seung-Taek Lim

The purpose of this study was to investigate changes in the levels of myokines in post- menopausal obese females (PMOF) after regular aerobic and resistance training. A community-based, randomized controlled trial study of 41 PMOF from Buk-gu Community Center in Chuncheon, Gangwon-do, Republic of Korea, was conducted from November 2017 through October 2018. These participants were randomly assigned to an aerobic exercise group (n = 21) or a resistance exercise group (n = 20). The 12-week exercise program was conducted three days a week (Monday, Wednesday, and Friday). Body composition, physical fitness, and myokines were measured at baseline, 6 weeks, and 12 weeks. The two-way within-factor ANOVA revealed group × time interaction for body mass index (BMI, p < 0.05). In the resistance exercise group, muscle endurance (p < 0.001), power (p < 0.01), and agility (p < 0.001) improved significantly at 12 weeks compared to baseline and 6 weeks. In the aerobic exercise group, muscle strength (p < 0.05), flexibility (p < 0.05), muscle endurance (p < 0.001), and agility (p < 0.001) were greater at 12 weeks compared to baseline and 6 weeks. The levels of IL-6 (p < 0.001), IL-15 (p < 0.001), and BDNF (p < 0.001) were greater at 12 weeks compared to baseline and 6 weeks in both exercise groups. Aerobic exercise training and resistance exercise training changed the levels of myokines and improved body composition and physical fitness in PMOF. These findings provide preliminary evidence that PMOF need to exercise or perform physical activity to improve or maintain their levels of myokines and physical fitness.


2013 ◽  
Vol 7 (11-12) ◽  
pp. 692 ◽  
Author(s):  
Daniel Santa Mina ◽  
Michael K. Connor ◽  
Shabbir M.H. Alibhai ◽  
Paul Toren ◽  
Crissa Guglietti ◽  
...  

Background: Androgen deprivation therapy (ADT) has significant deleterious effects on body composition that may be accompanied by unfavourable changes in adipokine levels. While exercise has been shown to improve a number of side effects associated with ADT for prostate cancer, no studies have assessed the effect of exercise on adiponectin and leptin levels, which have been shown to alter the mitogenic environment.Methods: Twenty-six men with prostate cancer treated with ADT were randomized to home-based aerobic exercise training or resistance exercise training for 24 weeks. Adiponectin, leptin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3) were analyzed by ELISA (enzyme-linked immunosorbent assay), in addition to physical activity volume, peak aerobic capacity, and anthropometric measurements, at baseline, 3 months and 6 months.Results: Resistance exercise significantly reduced IGF-1 after 3 months (p = 0.019); however, this change was not maintained at 6 months. At 6 months, IGFBP-3 was significantly increased compared to baseline for the resistance training group (p = 0.044). In an exploratory analysis of all exercisers, favourable changes in body composition and aerobic fitness were correlated with favourable levels of leptin, and favourable leptin:adiponectin and IGF-1:IGFBP-3 ratios at 3 and 6 months.Conclusions: Home-based exercise is correlated with positive changes in adipokine levels and the IGF-axis that may be related to healthy changes in physical fitness and body composition. While the improvements of adipokine markers appear to be more apparent with resistance training compared to aerobic exercise, these findings must be considered cautiously and require replication from larger randomized controlled trials to clarify the role of exercise on adipokines and IGF-axis proteins for men with prostate cancer.


2005 ◽  
Vol 30 (2) ◽  
pp. 233-245 ◽  
Author(s):  
Florin M. Malita ◽  
Antony D. Karelis ◽  
Emil Toma ◽  
Remi Rabasa-Lhoret

HIV infection and its treatment is associated with unfavourable metabolic and morphological abnormalities. These metabolic abnormalities, particularly alterations in body composition and fat distribution, may increase the risk for cardiovascular and metabolic complications, as well as reduce functional independence and lower self-esteem. Thus there is an urgent need to develop interventions intended to manage secondary side effects of HIV or antiretroviral therapy-related complications. In poly-treated patients, nonpharmacological interventions are a logical first step. Exercise training in particular may help alleviate some of the metabolic adverse effects associated with antiretroviral therapy by favourably altering body composition and patterns of body fat distribution. Studies have shown that exercise training, particularly aerobic training, can help reduce total body and visceral fat, as well as normalizing lipid profiles in HIV-infected patients. The results for resistance training, however, are less conclusive. Knowledge of the use of resistance and aerobic training and its attendant effects on insulin resistance and adipocytokines may represent an effective nonpharmacologic means for treating metabolic complications of HIV-infected persons who are receiving appropriate antiretroviral therapy. In this brief review we examine the effects of aerobic and resistance training on body composition, body fat distribution, and selected metabolic outcomes. Key words: lipodystrophy, highly active anti-retroviral therapy, aerobic training, resistance training


Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Ralmony A Santos ◽  
Kleiton A Silva ◽  
Juliana D Perez ◽  
Nestor Schor ◽  
Dulce E Casarini ◽  
...  

Previous studies from our laboratory have demonstrated that chronic diabetes in rats results in cardiomyopathy, associated with sympathetic nervous system (SNS) hyperactivity. On the other hand, it is well known that the beneficial cardiovascular effects of exercise training in diabetes are due in part to normalization of the sympathetic outflow and improvement in the responsiveness of the myocardium to autonomic stimulation. Recently, resistance training (RT) has been recognized as a useful therapeutic tool for the treatment of chronic diseases and similar to aerobic exercise, has been reported to improve metabolic profile and body composition. Therefore, the aim of this study was to evaluate the effect of moderate-intensity RT on circulating and cardiac catecholamines concentration, to understand whether this type of exercise is also associated with cardiovascular protection. Wistar rats (3 months old) were randomized into: control (C), diabetic (D), diabetic + RPT (DR) and diabetic + APT (DA). Animals were made diabetic with a single tail injection of streptozotocin (STZ, 50 mg/Kg). Resistance exercise training was performed on a vertical ladder (5 days/week, 8 weeks) at 40-60% maximal load, and moderate aerobic training was performed on a treadmill (5 days/week, 8 weeks). Diabetes significantly increased plasma concentration of adrenaline (D: 5.3 ± 1.0 vs. C: 4.1 ± 0.6 ng/mL) and noradrenaline (D: 14.5 ± 0.2 vs. C: 3.1± 0.8 ng/mL), and both exercise modalities induced a significant reduction of them: adrenaline (DR: 1.1 ± 0.3; DA: 0.7 ± 0.16 vs. D: 5.3 ± 1.0 ng/mL) and noradrenaline (DR: 1.0 ± 0.2; DA: 0.7 ± 0.1 vs. D: 14.5 ± 0.2 ng/mL). Cardiac concentration of noradrenaline was also increased in diabetic group (D: 62 ± 7 vs. CS: 34 ± 6 pg/g) and only aerobic exercise was capable to reduce its concentration in heart tissue (DA: 30 ± 6 vs. D: 62 ± 7; DR: 55 ± 7 pg/g). The results from the present study show for the first time additional beneficial effects of RT on modulating SNS activity in diabetes. Moreover, considering that RT does not modulate cardiac catecholaminergic secretion, it also highlights the importance of aerobic training in diabetes treatment. Financial Support: FAPESP, CAPES, CNPq


2007 ◽  
Vol 39 (Supplement) ◽  
pp. S59
Author(s):  
Bradley C. Nindl ◽  
Joseph A. Alemany ◽  
Alexander P. Tuckow ◽  
Jeffery S. Staab ◽  
Kevin R. Rarick ◽  
...  

2013 ◽  
Vol 11 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Maria Fernanda Bottino Roma ◽  
Alexandre Leopold Busse ◽  
Rosana Aparecida Betoni ◽  
Antonio Cesar de Melo ◽  
Juwando Kong ◽  
...  

OBJECTIVE: To compare the effects of physical fitness and function on older adults in two programs of supervised exercise activity: resistance training and aerobic exercise. METHODS: This study is a randomized, prospective clinical trial composed of sedentary elderly people who did not have contraindications to exercise. Participants were divided into two groups: group one performed 6 exercises of resistance training twice a week, and group two participated in walking activity for 30 minutes twice a week. Functional assessment (time 0,6 and 12 months) was measured by the Short Physical Performance Battery (time to sit or stand, gait speed, and balance), flexibility test, and the six-minute walking test. We randomly selected 96 patients: 46 in the Resistance Training Group and 50 in the Aerobic Exercise Group. In the Resistance Training Group, 46 attended the first assessment and 20 attended until the third section. In the Aerobic Exercise Group, 50 attended the first assessment and 12 attended until the third assessment. RESULTS: Mean age was 68.8 years in the Resistance Training Group and 69.1 years in the Aerobic Exercise Group. The Resistance Training Group showed improvement in the sit/stand (p=0.022), balance with feet in a row (p=0.039) and queued (p=0.001). The second showed a statistical difference in speed and balance with the feet lined up and the feet together (p=0.008; p=0.02; and p=0.043, respectively). Concerning flexibility, the Resistance Training Group had improvement (p=0.001), whereas in the Aerobic Exercise Group, no significant difference was seen (p=0.359). Both groups had improvement in the six-minute walking test, but no significant improvement was seen in the Aerobic Exercise Group (p=0.033). CONCLUSION: Both groups showed improvement in physical fitness. No statistical difference was seen when groups was compared in the short physical performance battery, flexibility, and six-minute walking test.


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