Recreational Drug use and Risk of HIV Infection Among Young Men Who Have Sex with men: A Cross-Sectional Study in Tianjin, China

Abstract Background- Recreational drug use among young men who have sex with men (YMSM) was a public health issue of worldwide concern. Evidence had shown the relevance between recreational drug use and human immunodeficiency virus (HIV) infection. This study aimed to investigate the current prevalence state of recreational drug use among YMSM in Tianjin, discern the characteristics of YMSM who used recreational drugs or not and examine the interaction effect of recreational drug use and unprotected anal intercourse (UAI) on HIV infection.Methods- In 2018, a cross-sectional study was conducted in Tianjin, China. The snowball sampling method was used to recruit YMSM. Participants were recruited from gay bars, gay bathhouses, social network sites (WeChat, QQ, gay chat website), gay apps and peer referrals. Structured questionnaires were used to collect data.Results- A total of 1075 YMSM met the eligibility criteria and were included in the study eventually. The overall HIV prevalence was 4.3% (46/1075). Of all the recreational drugs involved in this study (rush poppers, methamphetamine, capsule No.0), rush poppers (406/517,78.5%) were the most popular among YMSM in Tianjin. Compared with non-drug users, drug users were more likely to have first sex earlier, be bisexual, be male sex worker (MSW), have a higher education level, seek sex partners through physical venues, engage in UAI, have sexually transmitted infection (STI), and receive HIV testing. Moreover, recreational drug use and UAI were associated with the increased risk of HIV infection [adjusted OR:3.6 (95%CI: 1.7-7.6) and 4.9 (95%CI: 2.2-10.4), respectively]. There was additive interaction of recreational drug use and UAI on HIV infection [relative excess risk due to interaction (RERI): 6.949 (95%CI: 0.011‐13.887); attributable proportion due to interaction (AP): 0.809 (95%CI: 0.578‐1.039)].Conclusions- Recreational drug use was common and correlated with HIV infection among YMSM in Tianjin. There was an urgent need to build novel targeted HIV prevention strategies to discern and reduce recreational drug use among YMSM in China.

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Recreational drug use and risk of HIV infection among men who have sex with men: A cross-sectional study in Shenzhen, China

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2017.09.004 ◽

2017 ◽

Vol 181 ◽

pp. 30-36 ◽

Cited By ~ 12

Author(s):

Chenlin Duan ◽

Lan Wei ◽

Yitian Cai ◽

Lin Chen ◽

Zhengrong Yang ◽

...

Keyword(s):

Drug Use ◽

Hiv Infection ◽

Cross Sectional Study ◽

Recreational Drug ◽

Sectional Study ◽

Cross Sectional ◽

Recreational Drug Use ◽

Sex With Men

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Recreational Drug Use, Polydrug Use and Sexual Behaviors Among Men Who Have Sex With Men in Southwestern China: A Cross-Sectional Study

Behavioral Medicine ◽

10.1080/08964289.2018.1538099 ◽

2019 ◽

Vol 45 (4) ◽

pp. 314-322 ◽

Cited By ~ 3

Author(s):

Yingxue Dai ◽

Patou Masika Musumari ◽

Huailiang Chen ◽

Yuling Huang ◽

Teeranee Techasrivichien ◽

...

Keyword(s):

Drug Use ◽

Sexual Behaviors ◽

Cross Sectional Study ◽

Southwestern China ◽

Recreational Drug ◽

Sectional Study ◽

Cross Sectional ◽

Polydrug Use ◽

Recreational Drug Use ◽

Sex With Men

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Association between recreational drug use and sexual practices among people who inject drugs in Southwest China: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2017-019730 ◽

2018 ◽

Vol 8 (6) ◽

pp. e019730 ◽

Cited By ~ 2

Author(s):

Shu Su ◽

Lei Zhang ◽

Feng Cheng ◽

Shunxiang Li ◽

Shifu Li ◽

...

Keyword(s):

Drug Use ◽

People Who Inject Drugs ◽

Southwest China ◽

Cross Sectional Study ◽

Sexual Practices ◽

Recreational Drug ◽

Sectional Study ◽

Cross Sectional ◽

Recreational Drug Use

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High-risk behaviour and HIV infection risk among non-local men who have sex with men with less than a single year's residence in urban centres: a multicentre cross-sectional study from China

Sexually Transmitted Infections ◽

10.1136/sextrans-2016-052744 ◽

2016 ◽

Vol 94 (1) ◽

pp. 51-54 ◽

Cited By ~ 8

Author(s):

Yan-qiu Yu ◽

Jun-jie Xu ◽

Qing-hai Hu ◽

Hong-Jing Yan ◽

Zhe Wang ◽

...

Keyword(s):

Hiv Infection ◽

Risk Behaviour ◽

Cross Sectional Study ◽

Infection Risk ◽

Recreational Drug ◽

Sectional Study ◽

Cross Sectional ◽

High Risk Behaviour ◽

Non Local ◽

Sex With Men

ObjectivesTraditionally, subjects' migration status has usually been defined on the basis of their registered residency status. We attempted to redefine migration based on the duration of residency in their cities of migration and to explore more precisely the impact of migration on HIV infection risk in men who have sex with men (MSM).MethodsA multisite cross-sectional study was conducted during 2012–2013 in seven Chinese cities. Questionnaire surveys were conducted and blood was drawn to test for antibodies to HIV, syphilis and herpes simplex virus-2 (HSV-2). MSM who were unregistered local residents and had resided in their cities of migration for ≤1 or >1 year were defined as migrant MSM, or transitional MSM, respectively.ResultsCompared with transitional MSM and local MSM, migrant MSM had poorer HIV knowledge and higher rates of high-risk behaviour, including earlier sexual debut, multiple sexual partners, participation in commercial sex and recreational drug use. Multivariate logistic regression analysis showed that HIV prevalence among migrant MSM was higher than local MSM (p<0.05). This relationship, however, did not hold for transitional MSM and local MSM (p>0.05). Male sex work, recreational drug use, syphilis infection and HSV-2 infection were independently associated with HIV infection among migrant MSM.ConclusionsNon-local MSM with shorter residence were at greater risk of HIV acquisition. More focus should be placed on HIV behavioural interventions targeting non-local MSM with temporary residence.

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Recreational drug use among Chinese MSM: results from a national-wide cross-sectional study

The Lancet ◽

10.1016/s0140-6736(16)31996-1 ◽

2016 ◽

Vol 388 ◽

pp. S69 ◽

Cited By ~ 2

Author(s):

Peizhen Zhao ◽

Songyuan Tang ◽

Cheng Wang ◽

Ye Zhang ◽

John Best ◽

...

Keyword(s):

Drug Use ◽

Cross Sectional Study ◽

Recreational Drug ◽

Sectional Study ◽

Cross Sectional ◽

Wide Cross ◽

Recreational Drug Use

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Recreational Drug Use among Chinese Men Who Have Sex with Men: A Risky Combination with Unprotected Sex for Acquiring HIV Infection

BioMed Research International ◽

10.1155/2014/725361 ◽

2014 ◽

Vol 2014 ◽

pp. 1-9 ◽

Cited By ~ 27

Author(s):

Jun-Jie Xu ◽

Han-Zhu Qian ◽

Zhen-Xing Chu ◽

Jing Zhang ◽

Qing-Hai Hu ◽

...

Keyword(s):

Drug Use ◽

Hiv Infection ◽

Sexual Behaviors ◽

Cross Sectional Study ◽

Unprotected Sex ◽

Recreational Drug ◽

Cross Sectional ◽

Hiv Prevention Intervention ◽

Increased Risk ◽

Recreational Drug Use

Objective. To investigate the prevalence of recreational drug use and its relationship with HIV infection among Chinese MSM.Methods. A cross-sectional study of 625 MSM was conducted in Shenyang, China. Questionnaires were administered to collect information on recreational drug use and sexual behaviors. Blood specimens were collected to test for HIV and syphilis antibodies.Results. Nearly a quarter (23.2%, 145/625) of participants reported ever using recreational drugs, among which alkyl nitrites (poppers) was the most frequently used drug (19.2%), followed by methylmorphine phosphate (5.1%), methamphetamine (4.0%), and ketamine (0.8%). The overall prevalence of HIV and syphilis was 9.6% and 10.4%, respectively. Multivariate logistic analysis showed that recreational drug use was significantly correlated with age ≤25 year (adjusted odds ratio [aOR] = 1.6, 95% CI, 1.1–2.9), single marital status (aOR = 2.1, 95% CI, 1.2–3.6), and seeking male sexual partners mainly through Internet (aOR = 1.8, 95% CI, 1.8–2.8). Recreational drug use was independently associated with an increased risk of HIV infection (aOR = 3.5, 95% CI, 2.0–6.2).Conclusions. Our study suggests that recreational drug use is popular among Chinese MSM and is associated with significantly increased HIV infection risk. HIV prevention intervention programs should reduce both drug use and risky sexual behaviors in this population.

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