scholarly journals A rare presentation of superficial, inter-muscular, cystic, extra-spinal schwannoma over upper back.

2020 ◽  
Author(s):  
Srinjoy Saha
Keyword(s):  
Signs And Symptoms ◽  
Surgical Excision ◽  
The Body ◽  
Thoracic Vertebrae ◽  
Rare Presentation ◽  
Complete Surgical Excision ◽  
Rare Tumours ◽  
S 100 ◽  
Diagnostic Signs ◽  
Upper Thoracic

Abstract Schwannomas are rare tumours arising from peripheral nerve sheath and are usually related to the spinal cord and spinal nerves. Contrast magnetic resonance imaging (MRI) usually helps in establishing a pre-operative diagnosis. Rarely, their manifestation may be surprisingly new. Here, a 44-year-old lady came to our clinic with a painless asymptomatic progressively enlarging swelling over her upper back. It was fluctuant, with absent neural signs and symptoms. MRI showed a benign, purely-cystic, superficial-intermuscular, extra-spinal swelling near the upper thoracic vertebrae. However, classical diagnostic signs of schwannoma were absent. Complete surgical excision was performed with smooth dissection through a well-defined plane between the lesion and surrounding muscles. A 6.5x5.0x2.5 cm oval lesion with a glistening whitish-grey capsule was excised, and the deep wound was reconstructed in multiple layers. Interestingly, it was not attached to any identifiable nerves. Histopathology showed typical hallmarks like Antoni A regions and Verocay bodies. Positive S-100 staining during immunohistochemistry established its diagnosis as schwannoma. The postoperative one-and-half-year follow-up period was uneventful. Cystic schwannomas can surprise and confuse clinicians by arising anywhere in the body and with atypical manifestations. Surgeons need to consider it in the differential diagnoses of any undiagnosed slowly-growing swelling, including purely-cystic ones and perform careful surgical dissection to avoid any inadvertent nerve damage.

scholarly journals A rare presentation of superficial, inter-muscular, cystic, extra-spinal schwannoma over upper back

2020 ◽  
Vol 3 (3) ◽  
pp. 103-106
Author(s):  
Srinjoy Saha
Keyword(s):  
Signs And Symptoms ◽  
Surgical Excision ◽  
The Body ◽  
Thoracic Vertebrae ◽  
Rare Presentation ◽  
Complete Surgical Excision ◽  
Rare Tumours ◽  
S 100 ◽  
Diagnostic Signs ◽  
Upper Thoracic

Schwannomas are rare tumours arising from peripheral nerve sheath and are usually related to the spinal cord and spinal nerves. Contrast magnetic resonance imaging (MRI) usually helps in establishing a pre-operative diagnosis. Rarely, their manifestation may be surprisingly new. Here, a 44-year-old lady came to our clinic with a painless asymptomatic progressively enlarging swelling over her upper back. It was fluctuant, with absent neural signs and symptoms. MRI showed a benign, purely-cystic, superficial-intermuscular, extra-spinal swelling near the upper thoracic vertebrae. However, classical diagnostic signs of schwannoma were absent. Complete surgical excision was performed with smooth dissection through a well-defined plane between the lesion and surrounding muscles. A 6.5x5.0x2.5 cm oval lesion with a glistening whitish-grey capsule was excised, and the deep wound was reconstructed in multiple layers. Interestingly, it was not attached to any identifiable nerves. Histopathology showed typical hallmarks like Antoni A regions and Verocay bodies. Positive S-100 staining during immunohistochemistry established its diagnosis as schwannoma. The postoperative one-and-half-year follow-up period was uneventful. Cystic schwannomas can surprise and confuse clinicians by arising anywhere in the body and with atypical manifestations. Surgeons need to consider it in the differential diagnoses of any undiagnosed slowly-growing swelling, including purely-cystic ones and perform careful surgical dissection to avoid any inadvertent nerve damage.

scholarly journals A Rare Presentation of Schwannoma as a Purely-Cystic Superficial-Intermuscular Extra-Spinal Swelling over Upper Back.

2020 ◽  
Author(s):  
Srinjoy Saha
Keyword(s):  
Surgical Excision ◽  
Thoracic Vertebrae ◽  
Rare Presentation ◽  
Complete Surgical Excision ◽  
Rare Tumours ◽  
S 100 ◽  
One Year ◽  
Atypical Presentations ◽  
Upper Thoracic

Abstract Schwannomas are rare tumours arising from peripheral nerve sheath. Here, a 44-year-old lady came to our clinic with an asymptomatic progressively-enlarging swelling over her upper back. It was fluctuant, with an absence of pain and tenderness. MRI showed a benign, purely-cystic, superficial-intermuscular, extra-spinal swelling nearby upper thoracic vertebrae. Complete surgical excision proceeded smoothly through a well-defined plane between the swelling and the muscles. It was not attached to any identifiable nerve. A 6.5x5.0x2.5 cm ovoid lesion with a glistening whitish-grey capsule was excised and wound reconstructed in layers. Histopathology showed hypercellular areas with nuclear palisading or oval-shaped Verocay bodies. Only S-100 tested positive amongst the five-antigen immunohistochemistry, thus establishing the diagnosis of a schwannoma. Postoperatively, a one-year follow-up period was uneventful. Schwannomas can surprise clinicians by arising anywhere and with atypical presentations. It needs to be in the differential diagnoses of any asymptomatic slowly-growing lesion.

scholarly journals A rare presentation of small diaphragmatic epidermoid cyst with extremely elevated serum CA19-9 level

2020 ◽  
Vol 102 (2) ◽  
pp. e23-e25
Author(s):  
M El-Khoury ◽  
A Bohlok ◽  
YA Sleiman ◽  
P Loi ◽  
E Coppens ◽  
...  
Keyword(s):  
Epidermoid Cyst ◽  
Elevated Serum ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
The Body ◽  
Intraluminal Pressure ◽  
En Bloc ◽  
Rare Presentation ◽  
Epidermoid Cysts ◽  
Complete Surgical Excision

Epidermoid cysts are rare lesions that can occur anywhere in the body. They are associated with elevated serum levels of CA 19-9. The spleen represents the most common site of intra-abdominal localisation. Only two cases of diaphragmatic epidermoid cyst are reported in the literature. We present the case of a 61-year-old woman with a small suprasplenic subdiaphragmatic cyst discovered during the investigation of left flank pain. The establishment of an adequate diagnosis was challenging due to the difficulty in specifying the exact localisation of the cyst, the extremely elevated CA 19-9 level of 19,000 and the high uptake on 18-fluoro-2-deoxy-D-glucose positron emission tomography. The definitive diagnosis followed complete surgical excision. Intra-abdominal epidermoid cysts are usually discovered incidentally on imaging for another reason. The cyst is lined by squamous epithelium responsible for the secretion of CA 19-9. The elevation of serum CA 19-9 is due to small rupture or increased intraluminal pressure followed by diffusion to the bloodstream. Surgery with en-bloc resection represents the optimal treatment to avoid any risk of recurrence. The definitive diagnosis is established by demonstrating positive immunohistopathological staining of epithelial cell to CA 19.9.

scholarly journals Surgical excision: an effective initial therapeutic option in the management of giant macrocystic lymphatic malformations in children

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Moaied A. Hassan ◽  
Hasan K. Gatea ◽  
Thura K. Ja’afar
Keyword(s):  
Therapeutic Option ◽  
Surgical Excision ◽  
Functional Results ◽  
The Body ◽  
Lymphatic Malformations ◽  
Therapeutic Modalities ◽  
Complete Surgical Excision ◽  
Cystic Tumors ◽  
Cystic Cavity ◽  
Embryologic Development

Abstract Background Lymphatic malformations are rare benign cystic tumors that result from localized disordered embryologic development of the lymphatic system and can develop anywhere in the body, predominantly in the head and neck. These lesions are classified according to the diameter of the largest cystic cavity within the lesion into microcystic and macrocystic types. Historically, surgical excision has been considered the mainstay of treatment and still remains the first therapeutic option of choice for many surgeons particularly for giant macrocystic lesions. Several alternative therapeutic modalities emerged including intralesional sclerotherapy and laser therapy with encouraging results. The study is designed to assess the effectiveness and safety of surgical excision as an initial therapeutic option in the management of these malformations. Results Asymptomatic mass with parental cosmetic and functional concerns was the mode of presentation in six (66.7%) patients. Seven (77.8%) patients were presented before the age of 2 years. Six (66.7%) of the patients had their lesions in the neck. Complete surgical excision was achieved in eight (88.9%) patients without any evident significant injury to vital neurovascular structures. None of the patients had any difficulties with breathing, swallowing, or phonation and cosmetic results were satisfactory in the majority (88.9%) of them. Conclusion Radical surgical excision of giant macrocystic lymphatic malformations in children is possible in experienced hands. It is an effective and safe initial therapeutic option and gives satisfactory esthetic and functional results.

scholarly journals A Case of Incidental Schwannoma Mimicking Necrotic Metastatic Lymph Node from Bladder Cancer

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 728
Author(s):  
Jeong-Hyouk Choi ◽  
Koo-Han Yoo ◽  
Dong-Gi Lee ◽  
Gyeong-Eun Min ◽  
Gou-Young Kim ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Metastatic Lymph Node ◽  
Imaging Study ◽  
Surgical Excision ◽  
The Body ◽  
Pathological Examination ◽  
Cystic Tumor ◽  
Complete Surgical Excision ◽  
Ultrasound Computed Tomography ◽  
Retroperitoneal Schwannoma

Background and Objectives: Retroperitoneal schwannoma is a very rare case of schwannoma which commonly occurs in the other part of the body. However, it is difficult to distinguish schwannoma from other tumors before pathological examination because they do not show specific characteristics on imaging study such as ultrasound, computed tomography (CT), and magnetic resonance image (MRI). Case summary: A 60-year-old male showed a retroperitoneal cystic tumor which is found incidentally during evaluation of coexisted bladder tumor. Neurogenic tumor was suspicious for the retroperitoneal tumor through pre-operative imaging study. Finally, a schwannoma was diagnosed by immunohistochemical examination after complete surgical excision laparoscopically. Conclusion: As imaging technology is developed, there may be more chances to differentiate schwannoma from other neoplasm. However, still surgical resection and histopathological examination is feasible for diagnosis of schwannoma.

scholarly journals Retroperitoneal pelvic schwannoma in pregnancy: a case report

2017 ◽  
Vol 6 (8) ◽  
pp. 3689 ◽  
Author(s):  
Nithya J. ◽  
Banumathy M. ◽  
Radha A.
Keyword(s):  
Spindle Cell ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Nerve Sheath Tumor ◽  
Ct Guided ◽  
Spindle Cell Neoplasm ◽  
Complete Surgical Excision ◽  
S 100 ◽  
Needle Aspiration Cytology ◽  
In Pregnancy

Solitary nerve sheath tumor such as Benign schwannomas arising in the pelvic retro peritoneum is infrequently reported. Retroperitoneal location accounts for 0.3-3.2% of primary schwannomas. We report a case of benign retroperitoneal pelvic schwannoma in pregnancy that was incidentally diagnosed when it presented with Preterm premature rupture of membranes and mechanical obstruction for labour. She underwent caesarean section and delivered a healthy baby. She was evaluated in the postoperative period by computerized tomography (CT) imaging studies and CT guided fine needle aspiration cytology (FNAC) was not diagnostic. Complete surgical excision of the tumor was achieved in the postpartum period. The adjacent vascular and urinary channels sustained no injuries and she had no neurologic deficit. Histology revealed spindle cell neoplasm composed of interlacing fascicles and sheets of spindle cell with focal areas of nuclear palisading and thick walled blood vessels. Immunohistochemistry was positive for S 100 suggesting schwannoma. Retroperitoneal location of schwannomas is rare and surgery is curative. Prognosis is good, since recurrence is rare. 

scholarly journals Nasolabial hamartoma: a rare case report

2020 ◽  
Vol 6 (7) ◽  
pp. 1397
Author(s):  
D. Senthamarai Kannan ◽  
G. Soundara Rajan ◽  
Veerasigamani Narendrakumar ◽  
V. K. Sathiya
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Surgical Excision ◽  
The Body ◽  
Nasolabial Fold ◽  
Tissue Development ◽  
Inborn Errors ◽  
Complete Surgical Excision ◽  
Rare Case Report

<p class="abstract">Nasolabial cysts are rare, nonodontogenic soft tissue developmental cysts occur in the maxillary lip and nasal alar regions. Patients usually presents with an asymptomatic soft swelling with obliteration of the nasolabial fold. Due to it's origin from entrapped epithelium in an embryonic fusion plane developmentally, this cyst is considered to be a Hamartoma. Hamartomas are non-neoplastic malformations, or inborn errors of tissue development. They are characterized by an abnormal mixture of tissues indigenous to that area of the body. Complete surgical excision is the accepted method of treatment. This report aimed to present a case of nasolabial cyst hamartoma, which is rare in presentation.</p>

scholarly journals A Huge Pelvic-Abdominal Malignant GIST Tumour in a Patient with Neurofibromatosis Type 1: Case Report and Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Islam Omar ◽  
Hani Alsaati ◽  
Ejaz Waris
Keyword(s):  
Signs And Symptoms ◽  
Neurofibromatosis Type ◽  
Imatinib Treatment ◽  
Ki 67 ◽  
Common Location ◽  
Rare Tumours ◽  
Gastrointestinal Tumours ◽  
S 100 ◽  
Abdominal Compartment

Gastrointestinal stromal tumours are rare tumours of the gastrointestinal tract (GIT) accounting for 0.1%–3% of all gastrointestinal tumours. The most common location is the stomach (55%) followed by the small bowel (31.8%), colon (6%), other various locations (5.5%), and the oesophagus (0.7%). They may also occur in extraintestinal locations. The signs and symptoms of GIST depend on the tumour’s location and size. Gastrointestinal bleeding is one of the most common symptoms. Other signs and symptoms include abdominal discomfort, pain or distention; intestinal obstruction, and weight loss. The association between the development of GISTs and neurofibromatosis 1 (NF1) has been established. NF1-associated GISTs tend to have a distinct phenotype, and the absence of KIT/PDGRFα mutations in turn has implications on further management when they do not respond well to imatinib treatment. Here, we present one of the largest GISTs reported in the literature with a total volume of 25.3×20×14 cm+27.9×23×8 cm and an overall weight of 7.3 kg, which developed in a 43-year-old female patient with NF1 and was resected on an emergency basis due to the rapid deterioration and development of abdominal compartment syndrome. Pathology assessment showed a malignant GIST composed of spindle cells with elongated nuclei with necrosis, marked pleomorphism and numerous giant cell. The mitotic count was >15/50 HPF, Ki 67 was 80%, and the lymphovascular invasion was clear. Immunohistochemistry investigations showed that Vimentin, CD117, and DOG1 were positive, while BCL-2 and CD99 were focal positives. Pan-CK, S-100, CD34, Desmin, SMA, and HMB-45 were negatives.

scholarly journals Granular Cell Tumor over the Mons Pubis: An Uncommon Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
M. Patabendige ◽  
D. J. Wickramasooriya ◽  
L. Dasanayake
Keyword(s):  
Soft Tissue ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
The Body ◽  
Complete Surgical Excision ◽  
Neural Origin ◽  
Labium Majus ◽  
Uncommon Tumor

Granular cell tumors are uncommon, usually benign, soft tissue neoplasms of neural origin. They occur throughout the body; vulval involvement is uncommon and labium majus is the commonest site in vulva. Complete surgical excision is the preferred treatment of choice to prevent recurrence. Here, we present a benign granular cell tumor over the mons pubis of vulva in a 27-year-old woman.

scholarly journals Sublingual Schwannoma: A Rare Clinical Entity reported in a Hypothyroid Female

2012 ◽  
Vol 3 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Sudhir Naik ◽  
S Ravishankara ◽  
Mohan K Appaji ◽  
MK Goutham
Keyword(s):  
Head And Neck ◽  
Surgical Excision ◽  
Neck Surgery ◽  
Clinical Entity ◽  
Malignant Degeneration ◽  
Rare Clinical Entity ◽  
Benign Schwannoma ◽  
Complete Surgical Excision ◽  
S 100 ◽  
Contrast Ct

ABSTRACT Background Schwannomas are solitary, encapsulated tumor usually attached to, or surrounded by a nerve and are not associated with von Recklinghausen's disease and rarely show malignant degeneration. Setting Department of ENT, Head and Neck Surgery, KVG Medical College, Sullia. Case report A 68-year-old female presented with pain at the left side of the tongue since 1 month. Also a firm to soft 7 × 5 cm sublingual swelling of long-standing duration was seen. FNAC was inconclusive and contrast CT showed a sublingual swelling with mild-contrast enhancement. Intervention Sublingual excision of the tumor was done under general anesthesia and the tumor enucleated. No complications were seen and the recovery was uneventful. Histopathological report came as benign schwannoma and immunoreactive to S- 100 protein. Conclusion Most of the intraoral schwannomas are managed by complete surgical excision and recurrence are not reported. Malignant transformation is not seen in any of the intraoral schwannomas but definite preoperative diagnosis is necessary to avoid wide excision when the tumors can be easily enucleated without recurrence. How to cite this article Naik SM, Goutham MK, Ravishankara S, Appaji MK. Sublingual Schwannoma: A Rare Clinical Entity reported in a Hypothyroid Female. Int J Head and Neck Surg 2012;3(1):33-39.

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