scholarly journals Granular Cell Tumor over the Mons Pubis: An Uncommon Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
M. Patabendige ◽  
D. J. Wickramasooriya ◽  
L. Dasanayake

Granular cell tumors are uncommon, usually benign, soft tissue neoplasms of neural origin. They occur throughout the body; vulval involvement is uncommon and labium majus is the commonest site in vulva. Complete surgical excision is the preferred treatment of choice to prevent recurrence. Here, we present a benign granular cell tumor over the mons pubis of vulva in a 27-year-old woman.

HPB Surgery ◽  
1993 ◽  
Vol 6 (4) ◽  
pp. 311-317 ◽  
Author(s):  
W. David Lewis ◽  
Joseph F. Buell ◽  
Roger L. Jenkins ◽  
Peter A. Burke

Granulosa cell tumors are rare benign tumors which may be found throughout the body. Rare cases are isolated within the biliary tree. If completely resected, surgical excision is curative.A case of biliary duct granulosa cell tumor is presented with review of the world’s literature on this topic.


2017 ◽  
Vol 21 (2) ◽  
pp. 116-118 ◽  
Author(s):  
Panayiotis Karakostas ◽  
Apostolos Matiakis ◽  
Eleftherios Anagnostou ◽  
Alexandros Kolokotronis

Summary Background/Aim: The present analysis focuses on examining a case series of eight patients diagnosed with a granular cell tumor located in the oral cavity. Case series: The patients’ clinical states were thoroughly studied, along with the histopathological and immunohistochemical examinations findings. Their surgical treatment and postoperative course are also within the scope of this analysis. Numerous histogenesis theories and the appropriate tumor treatment are mentioned within the article being always in accordance with the relative literature. Conclusions: Oral granular cell tumor is a benign oral disease of possible neural origin commonly located on the tongue. Surgical excision is the treatment of choice. In any case, histological and immunohistochemical examination confirm both the clinical diagnosis and the differential diagnosis between oral squamous cell carcinoma.


2005 ◽  
Vol 29 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Robert Brannon ◽  
Payal Anand

Clinicopathologic studies on the granular cell tumor, a submucosal benign soft-tissue neoplasm, have not addressed the pediatric and adolescent population. This study of patients from birth to 19 years of age describes clinically and microscopically 10 new cases and combines them with 24 well-documented pediatric cases previously published in the English-language literature. Of the 34, patient ages ranged from 3 to 19 years (mean age 14.5 years) with a female-to-male ratio of 3.3 to 1. The most common location was the tongue (50%) and lips (25%). In neoplasms whose epithelial findings were documented microscopically, a reactive pseudoepitheliomatous (pseudocarcinomatous) hyperplasia of the overlying epithelium occurred in 29%. The recurrence rate was less than 10% following conservative surgical excision. This study reveals that an oral granular cell tumor in the first decade of life is an uncommon event and discusses the importance of differentiating between squamous cell carcinoma and granular cell tumor.


2010 ◽  
Vol 35 (3) ◽  
pp. 192-193 ◽  
Author(s):  
Kenichiro Hamada ◽  
Tetsuho Fujimoto ◽  
Shinsuke Omori ◽  
Makoto Emori ◽  
Susumu Joyama ◽  
...  

2014 ◽  
Vol 99 (1) ◽  
pp. 45-47 ◽  
Author(s):  
Takaaki Fujii ◽  
Hiroki Morita ◽  
Satoru Yamaguchi ◽  
Soichi Tsutsumi ◽  
Takayuki Asao ◽  
...  

Abstract Granular cell tumor may be located anywhere in the body; however, the gastrointestinal tract is infrequently involved and anal granular cell tumors are extremely rare. We report herein a rare case of granular cell tumor in the anal region. In the current case, a 66-year-old Japanese woman was found to have a polypoid lesion in the anus with hemorrhoids. The mass detected as an anal polypoid lesion with ulceration was resected and diagnosed as granular cell tumor by histologic examination. Granular cell tumor of the anal region is rare, and benign perianal polypoid lesions are relatively uncommon clinical findings. They might present diagnostic challenges to surgeons and pathologists. Awareness of the differential diagnosis of granular cell tumor and careful microscopic examination might allow proper management and diagnosis.


1989 ◽  
Vol 28 (6) ◽  
pp. 970-975 ◽  
Author(s):  
Akira ISAKA ◽  
Takanori WATANABE ◽  
Kastuji OOMORI ◽  
Hando HAKOZAKI ◽  
Fumiko OOTSUKI ◽  
...  

Author(s):  
D. Senthamarai Kannan ◽  
G. Soundara Rajan ◽  
Veerasigamani Narendrakumar ◽  
V. K. Sathiya

<p class="abstract">Nasolabial cysts are rare, nonodontogenic soft tissue developmental cysts occur in the maxillary lip and nasal alar regions. Patients usually presents with an asymptomatic soft swelling with obliteration of the nasolabial fold. Due to it's origin from entrapped epithelium in an embryonic fusion plane developmentally, this cyst is considered to be a Hamartoma. Hamartomas are non-neoplastic malformations, or inborn errors of tissue development. They are characterized by an abnormal mixture of tissues indigenous to that area of the body. Complete surgical excision is the accepted method of treatment. This report aimed to present a case of nasolabial cyst hamartoma, which is rare in presentation.</p>


Author(s):  
Myung Woo Kim ◽  
Sun Hee Chang ◽  
Ick Soo Choi

<p class="abstract"><span lang="EN-US">A granular cell tumor (GCT) is a rare neoplasm. It grows slowly, presumably originates from a Schwann cell, and is typically benign. Histopathologically, GCTs are composed of loosely infiltrating sheets of large, pale, polyhedral cells with abundant granular eosinophilic cytoplasm and a pale, centrally situated nucleus. Immunohistochemically, GCTs express the S-100 protein and neuron-specific enolase. A GCT can occur anywhere in the body. Half of all GCTs occur in the head and neck regions, especially on the tongue, but they are rarely found in the nasal cavity. A GCT usually arises as a solitary tumor and can be confirmed only by a histologic examination. The appropriate treatment is excision of the lesion. </span>Here, we present a rare case of a GCT originating in the right posterior ethmoid sinus in the nasal cavity. A GCT originating in a posterior ethmoid sinus has not been reported thus far. In our case, a simple nasal polyp was found in the left ethmoid sinus of the patient. Thus, we initially misjudged the GCT in the right nasal cavity as a simple nasal polyp.</p>


2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Nathan P. Heinzerling ◽  
Shannon M. Koehler ◽  
Sara Szabo ◽  
Amy J. Wagner

Objective. Granular cell tumors arise from neurogenic mesenchymal stem cells and can occur anywhere throughout the body. They rarely present as breast masses and should be included in the differential diagnosis of pediatric breast neoplasms. We report a rare presentation of a pediatric breast granular cell tumor and a review of the literature.Participant. A 15-year-old female presented with an enlarging breast mass. She underwent ultrasound imaging and excisional biopsy, which revealed a granular cell tumor. Granular cell tumors of the breast are difficult to diagnose using ultrasound and mammography due to numerous similarities to other breast masses. Histopathologic staining best differentiates breast granular cell tumors from other breast masses with their positive staining for S100, CD68, and neurospecific enolase.Conclusion. Although rare, granular cell tumors of the breast should be considered as a possible diagnosis for pediatric breast masses to allow for proper management and follow-up for these patients. Although rare, these tumors do have malignant potential necessitating a correct and timely diagnosis.


Author(s):  
Yvonne White ◽  
Winslow Sheldon ◽  
Terrell Hoage ◽  
Robert West

Granular cell myoblastoma is a rare tumor of which the nature and origin has been controversial. The cytogenesis of this tumor has been suggested as a neoplastic derivation from adult or embryonic muscle tissue, a histiocytic storage phenomenon, of neural origin and as a neoplasm derived from Schwann cells.This report presents the ultrastructure of a spontaneously occurring granular cell tumor from the brain of a 22 month old female Sprague- Dawley rat. Gross examination revealed an oval, gray external mass 3x4 mm in size and located on the cerebellar dorsal surface. This tumor was connected by a narrow stalk to a tumor mass located in the molecular layer of the cerebellum. The external tumor and the stalk were excised for electron microscopy (EM) and the remaining tumor mass, brain, and stalk were processed for light microscopy (LM).


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