scholarly journals Associations of Snoring, Daytime Napping and Night Sleep Duration With Hyperuricemia in Rural Chinese Adults: the Henan Rural Cohort Study

2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Xiaotian Liu ◽  
Lulu Zhang ◽  
Yan Wang ◽  
Runqi Tu ◽  
...  

Abstract Background. Evidence on the association of snoring, daytime napping or sleep duration with hyperuricemia (HUA) was limited, especially in the resources-poor areas. This study aimed to investigate the independent and joint effect of snoring frequency, daytime napping and sleep duration with prevalence of HUA in rural Chinese adults. Methods. 29,643 participants aged 18-79 years were included from baseline survey of the Henan Rural Cohort Study. Sleep variables were assessed using the Pittsburgh Sleep Quality Index (PSQI). Multivariate logistic regression and linear regression models with HUA and serum uric acid level as dependent variables were conducted, respectively. Results. Of the 29,643 included adults, 3498 suffered from HUA. Compared to never snoring, the adjusted odds ratio (OR) and 95% confidence interval (CI) of HUA for rare snoring, occasional snoring and habitual snoring were 1.35 (1.17, 1.56), 1.30 (1.14, 1.47) and 1.59 (1.47, 1.73), respectively. Compared with no napping, participants who had daytime napping of 61-90 and >91 min were associated with 29% and 30% increase in prevalence of HUA, respectively. But in night sleep duration groups, no significant associations were observed (all P>0.05). The positive associations between snoring and HUA were attenuated in older, female adults and those with chronic disease conditions. The joint of habitual snoring and longer daytime napping (≥61min) increased 63% prevalence on HUA. Conclusion. Snoring or daytime napping may independently increase the prevalence of HUA and serum uric acid (SUA) level. Moreover, habitual snoring and longer daytime napping might be jointly associated with a higher prevalence of HUA.Clinical Trial Registration The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). http://www.chictr.org.cn/showproj.aspx?proj=11375

2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Lulu Zhang ◽  
Xiaotian Liu ◽  
Runqi Tu ◽  
...  

Abstract Background. There are few studies on the hyperuricemia (HUA) and moderate to vigorous intensity physical activity (PA) and also hardly regarding sitting time (ST). The purpose of this study was to examine the independent and interactive association of PA and ST with HUA.Methods. A cross-sectional analysis was performed on 38,855 participants (aged 18-79) enrolled from the Henan Rural Cohort Study at baseline (2015 to 2017). PA and ST levels were assessed by using the International Physical Activity Questionnaire (IPAQ). HUA was defined as a serum uric acid level of >7.0 mg/dL for males and >6.0 mg/dL for females. Multivariable logistic regression and linear regression models were applied to examine the independent association between PA or ST and HUA and serum uric acid level. Interaction plots were used to visualize the interaction effects of PA and ST on HUA.Results. PA level was inversely related with serum uric acid level (β: -0.15, 95% confidence interval (CI): -0.22, -0.07), but ST was positively related with uric acid level (β: 2.12, 95% CI:1.90, 2.34). Metabolic equivalent (MET-hour/day) was associated with decreased prevalence of HUA (odds ratio (OR): 0.97, 95% CI: 0.96, 0.99), while per hour increased for ST was associated with increased HUA (OR:1.05, 95% CI: 1.04, 1.06). The interaction of PA and ST was significant (P<0.001). Conclusion. Exposure to higher ST was independently related to increased prevalence of HUA, while vigorous PA with a decreased HUA prevalence. Meanwhile, higher daily ST might attenuate the protective effect of PA on HUA.Clinical Trial RegistrationThe Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). http://www.chictr.org.cn/showproj.aspx?proj=11375


2020 ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Lulu Zhang ◽  
Xiaotian Liu ◽  
Runqi Tu ◽  
...  

Abstract BackgroundThere are few studies on the hyperuricemia (HUA) and moderate to vigorous intensity physical activity (PA) and also hardly regarding sitting time (ST). The purpose of this study was to examine the independent and interactive association of PA and ST with HUA.MethodsA cross-sectional analysis was performed on 38,855 participants (aged 18-79) enrolled from the Henan Rural Cohort Study at baseline (2015 to 2017). PA and ST levels were assessed by using the International Physical Activity Questionnaire (IPAQ). HUA was defined as a serum uric acid level of >7.0 mg/dL for males and >6.0 mg/dL for females. Multivariable logistic regression and linear regression models were applied to examine the independent association between PA or ST and HUA and serum uric acid level. Interaction plots were used to visualize the interaction effects of PA and ST on HUA.ResultsPA level was inversely related with serum uric acid level (β: -0.09, 95% confidence interval (CI): -0.16, -0.02), but ST was positively related with uric acid level (β: 2.04, 95% CI:1.82, 2.26). Metabolic equivalent (MET-hour/day) was associated with decreased prevalence of HUA (odds ratio (OR): 0.98, 95% CI: 0.96, 0.99), while per hour increased for ST was associated with increased HUA (OR:1.05, 95% CI: 1.04, 1.06). The interaction of PA and ST was significant (P<0.001).ConclusionExposure to higher ST was independently related to increased prevalence of HUA, while vigorous PA with a decreased HUA prevalence. Meanwhile, higher daily ST might attenuate the protective effect of PA on HUA.Clinical Trial RegistrationThe Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). http://www.chictr.org.cn/showproj.aspx?proj=11375


2013 ◽  
Vol 16 (17) ◽  
pp. 852-858 ◽  
Author(s):  
Adel Gouri ◽  
Aoulia Dekaken ◽  
Ahmed Aimen Bentorki ◽  
Amel Touaref ◽  
Amina Yekhlef ◽  
...  

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Xiaokang Dong ◽  
Yuqian Li ◽  
Lulu Zhang ◽  
Xiaotian Liu ◽  
Runqi Tu ◽  
...  

Abstract Background There are few studies on the hyperuricemia (HUA) and moderate to vigorous intensity physical activity (PA) and also hardly regarding sitting time (ST). The purpose of this study was to examine the independent and interactive association of PA and ST with HUA. Methods A cross-sectional analysis was performed on 38,855 participants (aged 18–79) enrolled from the Henan Rural Cohort Study at baseline (2015 to 2017). PA and ST levels were assessed by using the International Physical Activity Questionnaire (IPAQ). HUA was defined as a serum uric acid level of > 7.0 mg/dL for males and > 6.0 mg/dL for females. Multivariable logistic regression and linear regression models were applied to examine the independent association between PA or ST and HUA and serum uric acid level. Interaction plots were used to visualize the interaction effects of PA and ST on HUA. Results PA level was inversely related with serum uric acid level (β − 0.15, 95% confidence interval (CI) − 0.22, − 0.07), but ST was positively related with uric acid level (β 2.12, 95% CI 1.90, 2.34). Metabolic equivalent (MET-hour/day) was associated with decreased prevalence of HUA (odds ratio (OR) 0.97, 95% CI 0.96, 0.99), while per hour increased for ST was associated with increased HUA (OR 1.05, 95% CI 1.04, 1.06). The interaction of PA and ST was significant (P < 0.001). Conclusion Exposure to higher ST was independently related to increased prevalence of HUA, while vigorous PA with a decreased HUA prevalence. Meanwhile, higher daily ST might attenuate the protective effect of PA on HUA. Trial registration The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699).


Sign in / Sign up

Export Citation Format

Share Document