scholarly journals Indigenous Groups and Influenza: Protocol For A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Daniele Evelin Alves ◽  
Ole Røgeberg ◽  
Svenn-Erik Mamelund
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Indigenous Populations ◽  
Influenza Pandemics ◽  
Indigenous Groups ◽  
Combining Data ◽  
Registration Number ◽  
The Impact ◽  
Academic Search ◽  
Historical Periods

Abstract Background: Several studies have documented that indigenous groups have been disproportionally hit by previous pandemics, with some exceptions. The objective of this review and meta-analysis is to provide a comprehensive historical overview of pre-COVID impact of influenza on indigenous groups by combining data from the last five influenza pandemics and seasonal influenza up to date. Methods/Principle Findings: The review will include peer-reviewed original studies published in English, Spanish, Portuguese, Swedish, Danish and Norwegian. Records will be identified through systematic literature search in eight databases: Embase, Medline, Cinahl, Web of Science, Academic Search Ultimate, SocIndex, ASSIA and Google Scholar. Results will be summarized narratively and using meta-analytic strategies. Discussion: To our knowledge, there is no systematic review combining historical data on the impact of both seasonal and pandemic influenza on indigenous populations. By summarizing results across indigenous groups in different countries and historical periods, we aim to provide information on how strong the risk for influenza is among indigenous people, and how consistent this risk is across groups, areas and time. Systematic review registration: PROSPERO registration number: CRD42021246391

scholarly journals Non-adherence to immunosuppressants following renal transplantation: a protocol for a systematic review

BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e015411 ◽  
Author(s):  
Abigail Hucker ◽  
Frances Bunn ◽  
Lewis Carpenter ◽  
Christopher Lawrence ◽  
Ken Farrington ◽  
...  
Keyword(s):  
Systematic Review ◽  
Renal Transplant ◽  
Data Extraction ◽  
Meta Analysis ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Data Extraction Form ◽  
Registration Number ◽  
Meta Analyses ◽  
The Impact

IntroductionAdherence to immunosuppressant medication is essential for renal transplant recipients. This review aims to summarise what is known about non-adherence, with a view to providing comprehensive evidence to inform strategies aimed at advancing adherent behaviour.Methods and analysisA systematic review of quantitative studies that report adherence to immunosuppressants in adult (over 18 years) renal transplant recipients. The review will follow the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines; study quality will be assessed using the Downs and Black checklist. Systematic searches will be completed across relevant databases. Two reviewers will independently extract data using a predefined data extraction form. We will summarise the operationalisation of adherence across studies and use narrative synthesis to identify factors associated with non-adherence. A meta-analysis will be conducted if there is sufficient homogeneity, and available data, across studies to estimate the prevalence of non-adherence in renal transplant recipients. Heterogeneity will be assessed using the I2test. Survival analysis will be conducted to estimate hazard ratios to explore the impact of non-adherence on graft survival, graft failure and patient survival.Ethics and disseminationFindings will be published in a peer-reviewed journal and disseminated at conferences for professionals and researchers. Review outcomes will help support clinical practice by highlighting the extent of non-adherence among adults, and in doing so, signpost the need for suitable intervention.Trial registration numberPROSPERO registration number (CRD42016038751).

The Impact of Sleep Disorders on Functional Recovery and Participation Following Stroke: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 34 (11) ◽  
pp. 1050-1061
Author(s):  
George D. Fulk ◽  
Pierce Boyne ◽  
Makenzie Hauger ◽  
Raktim Ghosh ◽  
Samantha Romano ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Functional Recovery ◽  
Meta Analysis ◽  
Functional Limitations ◽  
Rehabilitation Professionals ◽  
Registration Number ◽  
The Mean ◽  
The Impact

Background Adequate sleep is vital for health and quality of life. People with stroke and a concomitant sleep disorder may have poorer outcomes than those without a sleep disorder. Objective To systematically evaluate the published literature to determine the impact of sleep disorders on physical, functional recovery at the activity and participation level after stroke. Methods A systematic review was conducted using PubMed, CINAHL, Scopus, and PsycINFO. Studies were selected that reported outcomes on physical, functional recovery at the activity and participation levels in participants with stroke and a diagnosed sleep disorder. A meta-analysis was performed on included studies that reported Barthel Index (BI) and modified Rankin Scale (mRS) scores. Results: A total of 33 studies were included in the systematic review with 9 of them in the meta-analysis. The mean mRS score was 0.51 points higher in participants with stroke and sleep disorders versus participants with stroke without sleep disorder [95% CI: 0.23-0.78]. The mean BI score was 10.2 points lower in participants with stroke and sleep disorders versus participants with stroke without sleep disorder [95% CI: −17.9 to −2.6]. Conclusions People with stroke and a sleep disorder have greater functional limitations and disability than those without a sleep disorder. Rehabilitation professionals should screen their patients with stroke for potential sleep disorders and further research is needed to develop sleep and rehabilitation interventions that can be delivered in combination. PROSPERO registration number: CRD42019125562.

scholarly journals The Impact of CKD on the Prognosis of COVID-19: A Protocol for Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Ruiqi Liu ◽  
Ruiyu Mou ◽  
Xinyao Jin ◽  
Kang Yang ◽  
Junli Chen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Meta Analysis ◽  
Journal Citation Report ◽  
Cochrane Library ◽  
Primary Study ◽  
Severe Illness ◽  
Study Approach ◽  
Registration Number ◽  
The Impact

Abstract Background: COVID-19 is a serious respiratory disease currently causing a global pandemic. However, few studies have evaluated the prognosis of chronic kidney disease (CKD) patients infected with COVID-19. Given the comorbidities evident in CKD patients, we speculate that they are more likely to be susceptible to COVID-19 infection relative to healthy individuals. However, a systematic study is necessary to confirm the relationship between these two conditions.Methods: The Wanfang, China Science Journal Citation Report (VIP database), EMBASE, CNKI, Web of Science, PubMed, and Cochrane Library databases will be reviewed to identify relevant studies. The PRISMA-P and Cochrane Handbook guidelines were used to prepare a standardized table to extract data from all relevant studies in a uniform manner. Risk and quality assessment analyses will be conducted for all included studies, with Revman 5.3 and Stata 13.0 being used for all data analyses. The primary study outcome is the assessment of whether CKD is a risk factor associated with COVID-19 infection, and to establish whether CKD increases the risk of severe illness in those infected with COVID-19. Secondary outcomes include mortality rates in CKD patients with COVID-19.Results: This study approach will synthesize extant studies into a single systematic review and meta-analysis in order to establish whether or not CKD is a risk factor associated with the development of critical COVID-19 illness, and whether CKD patients are at a higher risk of being infected by COVID-19.Conclusion: These results will provide a basis for the clinical treatment of COVID-19 in those with CKD.Systematic Review registration: CRD42020216330（PRORPERO registration number）

scholarly journals Misuse of medication in adult substance misuse services: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e047283
Author(s):  
Rosalind Gittins ◽  
Louise Missen ◽  
Ian Maidment
Keyword(s):  
Systematic Review ◽  
Substance Misuse ◽  
Data Extraction ◽  
Meta Analysis ◽  
Grey Literature ◽  
Opioid Analgesics ◽  
Physical And Mental Health ◽  
Qualitative Synthesis ◽  
Treatment Services ◽  
The Impact

IntroductionThere is a growing concern about the misuse of over the counter (OTC) and prescription only medication (POM) because of the impact on physical and mental health, drug interactions, overdoses and drug-related deaths. These medicines include opioid analgesics, anxiolytics such as pregabalin and diazepam and antidepressants. This protocol outlines how a systematic review will be undertaken (during June 2021), which aims to examine the literature on the pattern of OTC and POM misuse among adults who are accessing substance misuse treatment services. It will include the types of medication being taken, prevalence and demographic characteristics of people who access treatment services.Methods and analysisAn electronic search will be conducted on the Cochrane, OVID Medline, Pubmed, Scopus and Web of Science databases as well as grey literature. Two independent reviewers will conduct the initial title and abstract screenings, using predetermined criteria for inclusion and exclusion. If selected for inclusion, full-text data extraction will be conducted using a pilot-tested data extraction form. A third reviewer will resolve disagreements if consensus cannot be reached. Quality and risk of bias assessment will be conducted for all included studies. A qualitative synthesis and summary of the data will be provided. If possible, a meta-analysis with heterogeneity calculation will be conducted; otherwise, Synthesis Without Meta-analysis will be undertaken for quantitative data. The reporting of this protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Ethics and disseminationEthical approval is not required. Findings will be peer reviewed, published and shared verbally, electronically and in print, with interested clinicians and policymakers.PROSPERO registration numberCRD42020135216.

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