scholarly journals Non-sebaceous Lymphadenoma of the Thymus: a Case Report

Author(s):  
Wu Shanlian ◽  
Bai Yuping ◽  
Xie xunlu ◽  
Guo Guangxiu

Abstract Background: non-sebaceous lymphadenoma (NSL) is a rare benign tumor with a predominant lymphoid background within which is embedded solid or duct-like structures squamous epithelial nests, lacking of sebaceous differentiation. Non-sebaceous lymphadenoma most commonly arises within the salivary glands. However, Non-sebaceous lymphadenoma arises in the thymus have not been reported.Case presentation: A 53-year-old female patient, computed tomography (CT) scan of the chest for patient showed a nodular (19 ×13 × 16-mm) in the anterior mediastinum, and with mild homogeneous enhancement on contrast-enhanced CT. The patients underwent total thymectomy with removal of the anterior mediastinal nodule by thoracoscope via below the costal margin of the Xiphoid process. Microscopically, the tumor was composed of epithelial nests and prominent lymphoid stroma, with a capsule and clearly demarcated from the surrounding thymus tissue. The epithelial nests are arranged in solid nests or duct-like structures, lacking of sebaceous differentiation and cytological atypia. The pathological diagnosis was lymphadenoma, non-sebaceous type. There were no signs of recurrence 6 months after the surgery.Conclusions: There are very few reported cases of non-sebaceous lymphadenoma occurred in thymus in the medical literature. So accurate understanding of the histopathologic diagnosis of this rare tumor is important to avoid unnecessary overtreatment.

2016 ◽  
Vol 4 (1) ◽  
pp. 274
Author(s):  
Ritika Khurana ◽  
Anju Aggarwal ◽  
Aashima Dabas ◽  
Natasha Gupta

A female neonate presented with progressive abdominal distension. Liver was palpable, 11 cm below costal margin and a spleen of 10 cm. USG abdomen revealed massive hepatomegaly with multiple nodules in liver, kidney size and texture being normal. Contrast enhanced CT scan of the abdomen was suggestive of enlarged multinodular liver with splenomegaly. Liver biopsy revealed replacement of liver architecture by small rounded cells, which were positive for synaptophysin and S100 stains suggestive of neuroblastoma. A repeat abdominal radiological evaluation revealed a small 2 x 1 cm mass in left suprarenal area. Neuroblastoma stage 4S presenting as hepatomegaly is rare.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Toru Imagami ◽  
Satoru Takayama ◽  
Yohei Maeda ◽  
Ryohei Matsui ◽  
Masaki Sakamoto ◽  
...  

Background. Schwannoma arises from Schwann’s cell of the neural sheath. Schwannoma of the large intestine, particularly of the appendix, is rare. We report a case of appendiceal schwannoma resected using laparoscopic surgery. Case Presentation. A 75-year-old man was referred to our hospital for abdominal fullness and nausea since 2 months. Abdominal CT revealed a well-demarcated oval mass of 25 mm at the tip of the appendix. Contrast-enhanced CT revealed a lesion with gradually enhanced contrast from the arterial phase to the equilibrium phase. Abdominal US revealed a well-demarcated hypoechoic tumor. Preoperative diagnosis indicated appendiceal mesenchymal or neuroendocrine tumor. Ileocecal resection with D3 lymph node dissection was performed. Pathological and immunohistochemical findings confirmed the diagnosis of appendiceal schwannoma. Conclusions. For determining the surgical procedure of nonepithelial tumor of the appendix, preoperative diagnosis of mesenchymal or neuroendocrine tumors is required. However, appendiceal schwannoma is extremely rare, and its characteristic findings have not yet been established. Accumulating cases of appendiceal schwannomas is necessary for improving imaging diagnosis and surgical treatment.


2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Katsuyuki Suzuki ◽  
Satoshi Shiono ◽  
Kazuki Hayasaka ◽  
Makoto Endoh

Abstract Background Mediastinal hematoma rarely occurs after a minor traffic injury. Case presentation A woman in her forties was transferred to the emergency room by ambulance due to a traffic accident. Computed tomography (CT) revealed no abnormal findings, and she went home. Two days after the accident, the contrast-enhanced CT was repeated, which revealed cervical and mediastinal hematomas. Because it was possible that there was active bleeding from the right inferior thyroid artery, embolization of the right inferior thyroid artery was performed; however, her condition further deteriorated, so we performed emergency surgery to achieve hemostasis and remove the hematoma. Because of oozing from the right thyroid lobe, we performed right hemithyroidectomy and drainage of mediastinal space and right thoracic cavity. Since there was no bleeding site in the mediastinum, we thought that the mediastinal hematoma was due to bleeding from the thyroid gland. Her postoperative course was uneventful, and she is doing well at 9 months of follow-up after surgery. Conclusions It is possible that mediastinal hematoma might be caused by a minor traffic injury.


2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
C Schimmer ◽  
M Weininger ◽  
K Hamouda ◽  
C Ritter ◽  
SP Sommer ◽  
...  

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