scholarly journals Eosinophilic Pneumonia in a Patient With Ulcerative Colitis Treated With Mesalazine: a Case Report

2021 ◽  
Author(s):  
Yizhou Hu ◽  
Yan Chen
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Case Report ◽  
Rare Complication ◽  
Pulmonary Complications ◽  
Eosinophilic Pneumonia ◽  
Drug Induced ◽  
Case Presentation ◽  
Causative Drug ◽  
Inflammatory Bowel

Abstract Background: Mesalazine, also known as mesalamine or 5-ASA, is considered a safe drug and thus widely prescribed for Inflammatory bowel disease (IBD) patients. Mesalazine was previously recognized as a drug that can rarely cause pneumonia because lacking a sulfa component. Nevertheless, although still a rare complication, more and more cases have been reported nowadays. Case presentation: We describe the case of eosinophilic pneumonia (EP) in a 39-year-old woman with ulcerative colitis during treatment with mesalazine. We discontinued mesalazine after drug-induced EP was identified, and she made a prompt recovery.Conclusions: The diagnosis of EP is readily missed due to the rarity and the pulmonary complications of IBD. Since the treatment of pulmonary complications of IBD and EP varies, it is crucial to differentiate them. A prompt recovery can be expected in patients with EP after discontinuing the causative drug.

scholarly journals Cerebral Venous Sinus Thrombosis in a Patient with Ulcerative Colitis Flare

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
L. M. Conners ◽  
R. Ahad ◽  
P. H. Janda ◽  
Z. Mudasir
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Increased Risk ◽  
Inflammatory Bowel

Inflammatory bowel disease is characterized by a chronic inflammatory state and is therefore associated with abnormalities in coagulation and a hypercoagulable state. Cerebral venous sinus thrombosis is a rare complication of inflammatory bowel disease yet contributes significant morbidity and mortality to those affected. Early diagnosis is critical, as a delay in diagnosis portends a worse prognosis. This paper seeks to highlight the increased risk of venous sinus thrombosis in patients with inflammatory bowel disease. We start by discussing the case of a seventeen-year-old female who presented with ulcerative colitis flare and developed new-onset seizures, found to be caused by a large venous sinus thrombosis.

scholarly journals Acute granulomatous interstitial nephritis and ulcerative colitis: a case report and literature review

2018 ◽  
Vol 12 (1) ◽  
pp. 57
Author(s):  
Giorgia Comai ◽  
Olga Baraldi ◽  
Vania Cuna ◽  
Valeria Corradetti ◽  
Maria Cappuccilli ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Differential Diagnosis ◽  
Case Report ◽  
Interstitial Nephritis ◽  
Bowel Disease ◽  
Rare Case ◽  
Granulomatous Interstitial Nephritis ◽  
Recent Diagnosis ◽  
Inflammatory Bowel

Tubulo-interstitial nephritis (TIN) in patients affected by inflammatory bowel disease, both ulcerative colitis and Crohn’s disease, is usually considered as drug-associated to aminosalicylate. We report a rare case of granulomatous active tubulo-interstitial nephritis in a young patient with a recent diagnosis of ulcerative colitis naïve to aminosalicylate treatment. The patient has been successfully treated with steroids administration. Our purpose is to sensitize that TIN should always to be considered in differential diagnosis an extra-intestinal manifestation of bowel disease.

scholarly journals Norethisterone-induced cholestasis: A case report

2021 ◽  
Author(s):  
Safa moussaoui ◽  
mehdi abdelwahed ◽  
Nabil Ben Chaabene ◽  
Ahlem Bellalah ◽  
Najeh Ben Fadhel ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Contraceptive ◽  
Rare Complication ◽  
Oral Contraceptive Pill ◽  
Drug Induced ◽  
Case Presentation ◽  
Contraceptive Pill ◽  
Combined Oral Contraceptive

Case presentation: This case report concerns a 49-year-old woman who developed norethisterone drug -induced cholestasis, a progestin contraceptive, which is quite rare complication generally observed with estrogenic component of combined oral contraceptive pill.

scholarly journals Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced?

2019 ◽  
Vol 19 (02) ◽  
pp. 67-69
Author(s):  
Frances Feisi Sun ◽  
Nga Lai Chan ◽  
Tsz Ching Chan ◽  
Ka Long Leung ◽  
Yuk Wo Aaron Siu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Lupus Erythematosus ◽  
Bowel Disease ◽  
Systemic Lupus ◽  
Drug Induced ◽  
Drug History ◽  
History Of ◽  
Inflammatory Bowel

We report a 49-year-old lady with ulcerative colitis (UC) who subsequently developed systemic lupus erythematosus (SLE) ten years later. By reviewing the drug history and serum autoimmune panel, we hypothesize that systemic lupus erythematosus may occur in a patient with a history of inflammatory bowel disease as a coexisting disease, or triggered by drugs used in inflammatory bowel disease, such as disease-modifying anti-rheumatic drugs (DMARDs). This case raises the discussion that patients with Inflammatory bowel disease (IBD) may have a genetic predisposition for developing other autoimmune diseases, and explores the possibility of drugs used in the treatment of IBD as a trigger for SLE development. Being able to differentiate the two has important implications in management and prognosis.

scholarly journals Tracheobronchitis in ulcerative colitis: a case report of therapeutic response with infliximab and review of the literature

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Lisa Horgan ◽  
Siobhain Mulrennan ◽  
Lloyd D’Orsogna ◽  
Andrew McLean-Tooke
Keyword(s):  
Ulcerative Colitis ◽  
Case Report ◽  
Inhaled Corticosteroids ◽  
Rare Complication ◽  
High Dose ◽  
Clinical Effects ◽  
Case Presentation ◽  
First Case ◽  
Oral Corticosteroids ◽  
Symptomatic Remission

Abstract Background The extra-intestinal manifestation of tracheobronchitis is a rare complication of ulcerative colitis (UC). Here, we present a case of UC-related tracheobronchitis wherein the positive clinical effects of infliximab are demonstrated. Case presentation We report the case of a 39-year old woman who presented with a chronic productive cough on a distant background of surgically managed ulcerative colitis (UC). Our patient failed to achieve a satisfactory clinical improvement despite treatment with high dose inhaled corticosteroids, oral corticosteroids and azathioprine. Infliximab therapy was commenced and was demonstrated to achieve macroscopic and symptomatic remission of disease. Conclusions We present the first case report documenting the benefits of infliximab in UC-related tracheobronchitis.

scholarly journals A257 NEW ONSET ULCERATIVE COLITIS IN A PATIENT WITH KNOWN AUTOIMMUNE HEPATITIS TYPE 1

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 134-135
Author(s):  
M Hasan ◽  
Z Gallinger
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Autoimmune Hepatitis ◽  
Bowel Disease ◽  
Morphological Changes ◽  
Drug Induced ◽  
Inflammatory Bowel ◽  
Autoimmune Hepatitis Type 1 ◽  
New Onset

Abstract Background Elevated transaminases can occur in up to 17 per cent of cases of Inflammatory Bowel Disease (IBD)1, with many cases related to concurrent autoimmune conditions of the liver. Primary Sclerosing Cholangitis (PSC) is the most common autoimmune disease of the liver that is associated with IBD. Other causes of liver inflammation in patients with IBD can include Autoimmune Hepatitis (AIH). Aims We aim to report a case of new onset ulcerative colitis in a patient with autoimmune hepatitis type 1 in the absence of concomitant PSC. Methods Case report and review of literature. Results A 25-year-old male with painless jaundice and was found to have Autoimmune hepatitis type 1 with typical morphological changes, positive Antinuclear antibodies and elevated IgG levels. Histopathological exam of the liver did not show any direct changes to the bile ducts to suggest PSC. The patient was started on steroids and Mycophenolate Mofetil (MMF) and developed new onset diarrhea. Colonoscopy was performed and both endoscopic and pathological findings were suggestive of likely inflammatory bowel disease, although drug induced colitis (MMF) could not be excluded. Conclusions We conclude that there is a link between autoimmune hepatitis with IBD, in absence of concomitant PSC. Funding Agencies None

scholarly journals Spinal Epidural Abscess – A Rare Complication of Inflammatory Bowel Disease

2008 ◽  
Vol 22 (2) ◽  
pp. 177-180 ◽  
Author(s):  
Carl J Brown ◽  
Hussein Jaffer ◽  
Nasir Jaffer ◽  
Claude Burul ◽  
Robin S McLeod
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Restorative Proctocolectomy ◽  
Bowel Disease ◽  
Epidural Abscess ◽  
Rare Complication ◽  
Spinal Epidural Abscess ◽  
Immunocompromised Patients ◽  
Inflammatory Bowel ◽  
Spinal Epidural

Spinal epidural abscess is an uncommon but highly morbid illness. While it usually afflicts older, immunocompromised patients, this condition has been reported as a result of intestinal perforation in the setting of inflammatory bowel disease. Two cases of spinal epidural abscess in patients with inflammatory bowel disease are reported: one in a patient with Crohn’s disease and one in a patient with ulcerative colitis after restorative proctocolectomy.

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