Tracheobronchitis in ulcerative colitis: a case report of therapeutic response with infliximab and review of the literature

Abstract Background The extra-intestinal manifestation of tracheobronchitis is a rare complication of ulcerative colitis (UC). Here, we present a case of UC-related tracheobronchitis wherein the positive clinical effects of infliximab are demonstrated. Case presentation We report the case of a 39-year old woman who presented with a chronic productive cough on a distant background of surgically managed ulcerative colitis (UC). Our patient failed to achieve a satisfactory clinical improvement despite treatment with high dose inhaled corticosteroids, oral corticosteroids and azathioprine. Infliximab therapy was commenced and was demonstrated to achieve macroscopic and symptomatic remission of disease. Conclusions We present the first case report documenting the benefits of infliximab in UC-related tracheobronchitis.

Download Full-text

A Rare Complication Of Microwave Ablation For Renal Cell Carcinoma; Nephrocolic Fistula

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405617666210628165039 ◽

2021 ◽

Vol 17 ◽

Author(s):

Fatih Temel Yilmaz ◽

Lutfullah Sari ◽

Mahmut Esat Aykan ◽

Mehmet Gultekin ◽

Ilker Oz

Keyword(s):

Renal Cell Carcinoma ◽

Case Report ◽

Cell Carcinoma ◽

Renal Cell ◽

Microwave Ablation ◽

Rare Complication ◽

Case Presentation ◽

Ablation Therapy ◽

First Case ◽

Tumour Ablation

Introduction: Nephrocolic fistula is a pathological connection between the kidney and colon. Percutaneous tumour ablation therapy is a rare cause of iatrogenic nephrocolic fistula in the literature. Case Presentation: Interventional radiologists should be careful, especially in patients with repeated ablation. Granulation of tissue may lead to unexpected results secondary to tissue fragility and impedance changes. Conclusion: In addition, we should keep in mind that there is decreasing hydro dissection benefit in cases with the previous ablation. As far as we know, this is the first case report of an iatrogenic ephrocolic fistula after microwave ablation for recurrence renal cell carcinoma.

Download Full-text

Eosinophilic Pneumonia in a Patient With Ulcerative Colitis Treated With Mesalazine: a Case Report

10.21203/rs.3.rs-824407/v1 ◽

2021 ◽

Author(s):

Yizhou Hu ◽

Yan Chen

Keyword(s):

Ulcerative Colitis ◽

Inflammatory Bowel Disease ◽

Case Report ◽

Rare Complication ◽

Pulmonary Complications ◽

Eosinophilic Pneumonia ◽

Drug Induced ◽

Case Presentation ◽

Causative Drug ◽

Inflammatory Bowel

Abstract Background: Mesalazine, also known as mesalamine or 5-ASA, is considered a safe drug and thus widely prescribed for Inflammatory bowel disease (IBD) patients. Mesalazine was previously recognized as a drug that can rarely cause pneumonia because lacking a sulfa component. Nevertheless, although still a rare complication, more and more cases have been reported nowadays. Case presentation: We describe the case of eosinophilic pneumonia (EP) in a 39-year-old woman with ulcerative colitis during treatment with mesalazine. We discontinued mesalazine after drug-induced EP was identified, and she made a prompt recovery.Conclusions: The diagnosis of EP is readily missed due to the rarity and the pulmonary complications of IBD. Since the treatment of pulmonary complications of IBD and EP varies, it is crucial to differentiate them. A prompt recovery can be expected in patients with EP after discontinuing the causative drug.

Download Full-text

First reported case of penile prosthesis infection from brucellosis: case report

African Journal of Urology ◽

10.1186/s12301-020-00090-1 ◽

2020 ◽

Vol 26 (1) ◽

Author(s):

Nabil Nabil Moohialdin ◽

Ahmad Shamsodini ◽

Steven K. Wilson ◽

Osama Abdeljaleel ◽

Ibrahim Alnadhari ◽

...

Keyword(s):

Case Report ◽

Broad Spectrum ◽

Surgical Intervention ◽

Penile Prosthesis ◽

Raw Milk ◽

Prosthesis Infection ◽

Case Presentation ◽

First Case ◽

Milk Ingestion

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.

Download Full-text

A RARE ASSOCIATION OF CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY WITH ULCERATIVE COLITIS

10.36106/ijsr/6817759 ◽

2021 ◽

pp. 18-19

Author(s):

Nilima K. Shah ◽

Ankita Patel ◽

Umeshkumar Nakum ◽

Ravindra Patel

Keyword(s):

Ulcerative Colitis ◽

Ulcerative Colitis Patient ◽

Chronic Inflammatory Demyelinating Polyneuropathy ◽

Rare Complication ◽

Gastrointestinal Symptoms ◽

Demyelinating Polyneuropathy ◽

High Dose ◽

Initial Symptom ◽

Colitis Patient ◽

Rare Association

Chronic inammatory demyelinating polyneuropathy (CIDP) is a rare complication of Ulcerative colitis and it is uncertain whether it is associated with Ulcerative colitis itself or with its treatment. We describe a case of CIDP-like neuropathy as an initial symptom of Ulcerative colitis. A 17 years old male patient presented with symmetrical weakness of both lower extremities with paresthesia of both hand and feet. With impression of AIDP patient was treated with plasmapheresis and discharged on tapering steroid therapy. After 3 months again presented with bilateral weakness of all four limbs associated with diarrhea and fever. Patient was diagnosed with Ulcerative colitis ,so considering previous episode as 1st episode of CIDP and with rare association with Ulcerative colitis . Patient was treated with high dose of steroids and immunosuppressive therapy. Neurological and gastrointestinal symptoms remarkably improved after treatment.

Download Full-text

Myiasis Absent Wohlfahrtiimonas Chitiniclastica Bacteremia in a Lung Cancer Patient – A Case Report

10.21203/rs.3.rs-410141/v1 ◽

2021 ◽

Author(s):

Peter Dovjak ◽

Michael Kroissenbrunner ◽

Bernhard Iglseder

Keyword(s):

Lung Cancer ◽

Case Report ◽

Cancer Patient ◽

Lung Cancer Patient ◽

Chronic Wounds ◽

Lung Tumor ◽

Personal Hygiene ◽

Human Pathogen ◽

Case Presentation ◽

First Case

Abstract Background: A gruesome infection was found in a woman with advanced lung tumor and associated malnutrition. Worldwide, bacteremia with Wohlfartiimonas chitiniclastica was only found in 13 cases yet.Case presentation: This is the first case in Austria and the first case without infestation of maggots.Conclusions: This germ may be considered as an emerging human pathogen not only in patients with poor personal hygiene, difficult social circumstances, alcohol dependence or chronic wounds.AbstraktEine grauenhafte Infektion wurde bei einer Patientin mit fortgeschrittenem Lungentumor und Malnutrition gefunden. Bisher wurden weltweit erst 13 Fälle mit einer Wohlfahrtiimonas chitiniclastica - Bakteriämie beschrieben. Dieser erste Fall in Österreich manifestierte sich ohne eine Infestation mit Maden. Dieses Bakterium kann als neuer Krankheitserreger betrachtet werden, der nicht nur bei Patienten unter mangelnder Hygienebedingungen, schwierigen sozialen Verhältnissen, Alkoholabhängigkeit oder chronischen Wunden auftreten kann.

Download Full-text

Case Report. Extracorporeal Membrane Oxygenation in Nivolumab Associated Pneumonitis

The Journal of Critical Care Medicine ◽

10.1515/jccm-2017-0013 ◽

2017 ◽

Vol 3 (2) ◽

pp. 84-88

Author(s):

Thomas-Michael Schneider ◽

Friederike Klenner ◽

Franz Brettner

Keyword(s):

Case Report ◽

Extracorporeal Membrane Oxygenation ◽

Therapeutic Option ◽

High Dose ◽

Great Success ◽

Case Presentation ◽

Computed Tomographic ◽

Rehabilitation Hospital ◽

Membrane Oxygenation ◽

History Of

Abstract Background: Newly approved immunotherapeutic agents, like CTLA-4 inhibitors and antibodies against PD-1, are a promising therapeutic option in cancer therapy. Case presentation: A 74-year-old man, with a history of advanced stage melanoma and treatment with ipilimumab, pembrolizumab and nivolumab, was admitted to the hospital due to respiratory failure with hypoxemia and dyspnoea. He rapidly developed severe acute respiratory distress syndrome (ARDS), which required treatment in the intensive care unit which included mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Computed tomographic imaging (CT) showed signs of a pneumonitis, with an ARDS pattern related to the use of PD-1 antibodies. Treating the patient with high-dose immunosuppressive steroids led to an overall improvement. He was transferred to a rehabilitation hospital and subsequently to his home. Discussion and conclusion: This is a unique case report of a patient suffering a grade 4 adverse event under nivolumab who survived having been treated with ECMO. It highlights the possibility of associated adverse reactions as well as the use of ECMO in palliative care patients. ECMO can be of great success even in patients with malignancies, but careful decision making should be done on a case by case basis.

Download Full-text

Case report: a 5-year-old with new onset nephrotic syndrome in the setting of COVID-19 infection

BMC Nephrology ◽

10.1186/s12882-021-02520-w ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Kelsi M. Morgan ◽

Peace D. Imani

Keyword(s):

Nephrotic Syndrome ◽

Case Report ◽

Pediatric Patient ◽

Corticosteroid Therapy ◽

Clinical Remission ◽

Laboratory Findings ◽

Case Presentation ◽

The Third ◽

First Case ◽

New Onset

Abstract Background This is a case report of an asymptomatic SARS-CoV-2 infection associated with new-onset nephrotic syndrome in a pediatric patient. This is the third case of new-onset nephrotic syndrome in children associated with SARS-CoV-2 infection, but is the first case report describing a new-onset nephrotic syndrome presentation in a patient who had asymptomatic COVID-19 infection. Case presentation This is a case of a previously healthy 5 year old female who presented with new-onset nephrotic syndrome in the setting of an asymptomatic COVID-19 infection. She presented with progressive edema, and laboratory findings were significant for proteinuria and hypercholesterolemia. She was treated with albumin, diuretics, and corticosteroid therapy, and achieved clinical remission of her nephrotic syndrome within 3 weeks of treatment. Though she was at risk of hypercoagulability due to her COVID-19 infection and nephrotic syndrome, she was not treated with anticoagulation, and did not develop any thrombotic events. Conclusions Our case report indicates that SARS-CoV-2 infection could be a trigger for nephrotic syndrome, even in the absence of overt COVID-19 symptoms.

Download Full-text

Tocilizumab for massive refractory pleural effusion in an adolescent with systemic lupus erythematosus

Pediatric Rheumatology ◽

10.1186/s12969-021-00635-w ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Arianna De Matteis ◽

Emanuela Sacco ◽

Camilla Celani ◽

Andrea Uva ◽

Virginia Messia ◽

...

Keyword(s):

Pleural Effusion ◽

Lupus Erythematosus ◽

High Dose ◽

Common Symptom ◽

Systemic Lupus ◽

Malar Rash ◽

Case Presentation ◽

Double Stranded Dna ◽

First Case ◽

History Of

Abstract Background Pleural effusion in systemic lupus erythematous (SLE) is a common symptom, and recent studies demonstrated that IL-6 has a pivotal role in its pathogenesis. Case presentation We report a case of a 15 years old Caucasian boy with a history of persistent pleural effusion without lung involvement or fever. Microbiological and neoplastic aetiologies were previously excluded. Based on the presence of pleuritis, malar rash, reduction of C3 and C4 levels and positivity of antinuclear antibody (ANA) and anti-double stranded DNA (dsDNA), the diagnosis of juvenile SLE (JSLE) was performed. Treatment with high dose of intravenous glucocorticoids and mycophenolate mofetil was started with partial improvement of pleural effusion. Based on this and on adults SLE cases with serositis previously reported, therapy with intravenous tocilizumab (800 mg every two weeks) was started with prompt recovery of pleural effusion. Conclusion To the best of our knowledge, this is the first case of JSLE pleuritis successfully treated with tocilizumab.

Download Full-text

Patient re-presents to the clinic with reactive arthritis in the right hip after covid-19 infection: A case report

10.21203/rs.3.rs-230354/v1 ◽

2021 ◽

Author(s):

Kamyar Shokraee ◽

Soroush Moradi ◽

Tahereh Eftekhari ◽

Rasoul Shajari ◽

Maryam Masoumi

Keyword(s):

Case Report ◽

Reactive Arthritis ◽

Respiratory Symptoms ◽

Gastrointestinal Infection ◽

Case Presentation ◽

Sexually Transmitted ◽

Methyl Prednisolone ◽

First Case ◽

The Right

Abstract Background: SARS-COV-2, first reported in December 2019, usually presents with respiratory symptoms but can have various other manifestations and sequelae. One of the rare complications of COVID-19 infection is Reactive Arthritis. This complication is more likely to occur following sexually transmitted or gastrointestinal infection.Case presentation: Herein, we report a 58 years old woman hospitalized following COVID-19 infection and was discharged after a week. She consequently presented to the clinic ten days after her discharge, complaining of walking difficulties and radiating pain in her right hip. After ultrasound and MRI, she was diagnosed with reactive arthritis inflammation in the hip’s neck. Other known microorganisms responsible for reactive arthritis were ruled out before attributing it to the earlier COVID-19 infection. She reached remission after being treated using a combination of indomethacin and depot methyl-prednisolone for 14 days. Conclusion: To our knowledge, this is the first case of reactive arthritis caused by SARS-COV-2 in the hip. Further attention should be paid to symptoms occurring after an episode of infection with COVID-19 in order to expand our understanding of the disease and the symptoms with which it can manifest.

Download Full-text

Multiple polyurethane implant punctures during fat grafting: case report and review of the literature

BMC Surgery ◽

10.1186/s12893-020-00915-4 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Dmitry Batiukov ◽

V. Podgaiski ◽

D. Mikulich ◽

S. Kalinin

Keyword(s):

Case Report ◽

Breast Reconstruction ◽

Breast Augmentation ◽

Surgical Procedure ◽

Fat Grafting ◽

Review Of The Literature ◽

Level Of Evidence ◽

Case Presentation ◽

Tissue Ingrowth ◽

First Case

Abstract Background Breast augmentation with implants continues to be the most popular aesthetic surgical procedure performed worldwide. Fat grafting may improve the results of breast augmentation and breast reconstruction with implants. However, fat grafting to the breast with implants carries the risk of implant puncture. To our best knowledge this is the first case in which polyurethane implant puncture during fat grafting is described. Case presentation We report multiple bilateral implant punctures with the cannula during fat grafting in a patient who previously underwent breast reconstruction with polyurethane implants. Conclusions Implants that promote tissue ingrowth may be more prone to puncture with the cannula during fat grafting. Specific planning and surgical maneuvers decrease the risk of implant puncture. Level of evidence Level V, case report.

Download Full-text