scholarly journals Efficacy of Chlorhexidine Alcohol over Aqueous Povidone Iodine in Prevention of Surgical Site Infection

2015 ◽  
Vol 4 (12) ◽  
pp. 1966-1969
2020 ◽  
pp. 44-46
Author(s):  
Sonali Deshpande ◽  
Shrinivas Gadappa ◽  
Dhanashree Lahane ◽  
Sandeep Mannikatti

Objective: To evaluate the efficacy of pre-cesarean vaginal wash using 5% Povidone Iodine solution on rate of post-cesarean section (CS) surgical site infection and compared with No swabbing. Method: A Prospective Randomized controlled Trial was conducted in department of Obstetrics and Gynecology in Government medical college, Aurangabad. In interventional group, vaginal swabbing with a gauze pieces impregnated with 5% Povidone Iodine solution was done for 30 seconds. The swabbing of vagina was not performed in cases assigned to control group, however the standard surgical preparation of abdomen was done in a usual manner for both group. All subject received prophylactic antibiotic cover. Collected data was complied in pre-designed proforma and analysis was done using SPSS 15. Result: The risk of post operative fever and wound infection was significantly reduced in interventional group. No measure difference was noted in seroma and composite wound infection. Also less duration of hospital stay in interventional group was noted. No adverse effect of use of Povidone iodine was reported in the interventional group. Conclusion: Vaginal swabbing with 5% Povidone-iodine pre- LSCS is inexpensive and simple intervention even for low resource setting to decrease surgical site infection.


2019 ◽  
Vol 6 (4) ◽  
pp. 1214
Author(s):  
Asadulla Baig ◽  
Mohan Kumar K.

Background: Peritonitis secondary to hollow viscous perforation is one of the commonest emergencies encountered in general surgical practice. This randomized study aimed to compare the efficiency of Povidone iodine and Metronidazole in these cases by quantitative analysis of bacterial colony count in patients who have received peritoneal lavage with either of them.Methods: A total of 100 consecutive patients who presented with peritonitis secondary to hollow viscous perforation were enrolled in this study (February 2010 to February 2011) and systematically divided into 2 groups: peritoneal lavage with povidone iodine group and lavage with metronidazole group. The post-operative progress was assessed by comparing the pre-wash and post wash colony counts in both the groups, development of surgical site infection and duration of hospital stay.Results: The median age of the patients was 33 years (range: 12-75 years), with a male: female ratio of 3.8:1. Perforation of duodenal ulcer (67%) was the commonest cause of peritonitis with E. coli (65%) being the commonest organism isolated from the peritoneal fluid. Reduction in bacterial colony count was seen in both the groups of patients, however, there was significantly greater reduction in the patients who received lavage with Metronidazole (p=0.06). Incidence of surgical site infection was less in the Povidone iodine group though it did not reach statistical significance.Conclusions: The use of povidone iodine in peritoneal lavage significantly reduce the bacterial colony and may also result in fewer surgical site infections.


Author(s):  
Vishnu Priya Kesani ◽  
Sruthi Talasila ◽  
Sheela S. R.

Background: Caesarean section is one of the most common procedures performed. Recent studies found that surgical-site infection (SSI) was the most common healthcare-associated infection. Authors hypothesized that optimization of preoperative skin antisepsis may decrease postoperative infections. The objective was to establish the efficacy of chlorhexidine-based antiseptic protocol versus povidone-iodine protocol in reducing SSI for patients undergoing caesarean deliveries.Methods: This is a randomized prospective study conducted from April 2017 to September 2017 at a tertiary care center in India. Women who underwent caesarean sections were allocated into either group. Enrolled patients were randomly assigned to have the surgical site painted with chlorhexidine-alcohol preparation or painted with a solution of 10% povidone-iodine and then with surgical spirit. The outcomes were any SSI occurring within a week or during the 30 day follow up period of the surgery including any of: superficial or deep surgical site infection, or endometritis, according to Centers for Disease Control and Prevention definitions.Results: A total of 560 subjects (273 in the chlorhexidine group and 287 in the iodine group) qualified for the study. The number of surgical-site infection was significantly lower in the chlorhexidine group than in the iodine group (6.95% vs. 14.28%; P=0.005). Chlorhexidine–alcohol was significantly more protective than iodine-alcohol against both superficial incisional infections (5.49% vs. 10.10%, P=0.03) and deep incisional infections (1.46% vs. 4.18%, P=0.04).Conclusions: This study highlighted that Chlorhexidine-alcohol provided superior skin antisepsis in comparison to povidone iodine-alcohol.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Vincenzo De Luna ◽  
Federico Mancini ◽  
Fernando De Maio ◽  
Gabriele Bernardi ◽  
Ernesto Ippolito ◽  
...  

Background. Deep wound infection in spine surgery is a debilitating complication for patients and increases costs. The objective of this prospective study was to evaluate the efficacy of wound pulse irrigation with a dilute povidone-iodine solution in the prevention of surgical site infection.Methods. 50 patients undergoing spinal surgery were randomly divided into two groups (A and B) of 25 patients each. In group A, wounds were irrigated with dilute (3%) povidone-iodine solution through a low-pressure pulsatile device. In group B, wounds were irrigated with saline solution through a bulb syringe. In both groups, specimens for bacterial culture were harvested from surgical site before and after irrigation.Results. In group A, no surgical site infection occurred; in group B, deep wound infection was observed in 3 patients. In both groups, before irrigation some cultures have been found positive for bacterial contamination.Conclusion. Our study seems to support the idea that low-pressure pulsating lavage of surgical wounds with povidone-iodine diluted to a nontoxic concentration of 3% is an effective therapeutic adjunct measure to prevent surgical site infection in spine surgery. However, the number of the enrolled patients is small and a significant statistical analysis is not practicable. This trial is registered withNCT03249363.


2018 ◽  
Vol 90 (5) ◽  
pp. 1-7
Author(s):  
Wojciech Kolasiński

This paper presentes the current state of konwledge regarding the everlasting problem in surgery- surgical site infections. Introduction: Surgical site infections have accompanied humanity since the dawn of time. Development of medicinie has reduced their percentage, but still they are a huge problem to face with. Surgical site infections cause a significant increase in a cost of hospitalization. This is the main reason why the whole scientific world is looking for prevention of these complications. Materials and methods: The aim of the paper is to present current views on the etiology and methods of prevention of surgical site infection. Results: Patients own pathogens are most often responsible for surgical site infections. In hospitalizations over 5-7 days exogenous and hospital flora have the advantage. The most common isolated pathogen is Staphylococcus aureus. The percentage of MRSA-resistant methicillin strains is increasing. Pre-operative antibiotic therapy reduces the frequency of surgical site infection in many surgical procedures. Time of administration, type and dose of antibiotic play an important role in preventing post-operative infections. Pre-operative skin antiseptic is also important. The two most commonly used ingredients are chlorhexidine gluconate and povidone iodine. Recent reports point the chlorhexidine alcohol solution as an agent with a higher degree of efficacy. Conclusions: In 2017 Centers for Disease Control and Prevention published the new guidelines for prevention of surgical site infections. This practical tips and tricks should be implemented to every surgical procedure.


2011 ◽  
Vol 98 (4) ◽  
pp. 603-603
Author(s):  
I. Fournel ◽  
M. Tiv ◽  
C. Hua ◽  
M. Soulias ◽  
K. Astruc ◽  
...  

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