RETROPERITONEAL NON-ORGAN LIPOSARCOMAS: THE MODERN CONCEPT

Objective: to conduct a systematic literature review of the published studies on retroperitoneal non-organ liposarcomas.Material and Methods. A literature search was performed using Pubmed, Elibrary, COSMIC databases. The data of retrospective and prospective clinical trials were analyzed. Results. The article reviews contemporary data on epidemiology, classification, clinicalmorphological and molecular-genetic characteristics, as well as diagnosis and treatment of retroperitoneal non-organ liposarcomas. Conclusion. Retroperitoneal sarcomas account for about 13 % of all types of soft tissue sarcomas. Liposarcoma is the most common retroperitoneal mesenchymal tumor. Diagnosis and treatment of non-organ retroperitoneal liposarcoma remain challenging due to poor long-term treatment outcomes. As experience is gained with the diagnosis and treatment of retroperitoneal nonorganic liposarcomas, changes occur in the system of understanding the problem that determines the strategy for providing medical care in this category of patients. The article presents modern concept of retroperitoneal non-organ liposarcomas.

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Angioplasty of iliac vessels and the part of abdominal aorta in the female patient with non-organ retroperitoneal liposarcoma

Russian Journal of Oncology ◽

10.18821/10289984-2016-21-6-303-307 ◽

2016 ◽

Vol 21 (6) ◽

pp. 303-307

Author(s):

I. S Stilidi ◽

Maksim P. Nikulin ◽

M. G Abgaryan ◽

O. E Kalinin ◽

O. A Anurova

Keyword(s):

Female Patient ◽

Abdominal Aorta ◽

Iliac Artery ◽

Term Treatment ◽

Cancer Centers ◽

Retroperitoneal Liposarcoma ◽

Long Term Treatment ◽

Large Vessels ◽

Surgery Resection

The involvement of large vessels in the tumor process is the cause of the refusal of the surgery. Resection of aorta, even in specialized cancer centers is carried out very rarely. We report the result of long-term treatment of the female patient with retroperitoneal liposarcoma with invasion of the iliac artery, and 22 months later - in aorta.

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Long-Term Treatment Results in Soft Tissue Sarcomas of the Thoracic Wall Treated with Pre-or-Postoperative Radiotherapy - a Single Institution Experience

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2014.15.22.9949 ◽

2014 ◽

Vol 15 (22) ◽

pp. 9949-9953 ◽

Cited By ~ 5

Author(s):

Didem Colpan Oksuz ◽

Sevim Ozdemir ◽

Nuri Kaydihan ◽

Sergulen Dervisoglu ◽

Murat Hiz ◽

...

Keyword(s):

Soft Tissue ◽

Postoperative Radiotherapy ◽

Soft Tissue Sarcomas ◽

Term Treatment ◽

Thoracic Wall ◽

Single Institution ◽

Treatment Results ◽

Long Term Treatment

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Lithium and Suicide Risk in Bipolar Disorder

CNS Spectrums ◽

10.1017/s1092852900023233 ◽

2000 ◽

Vol 5 (S1) ◽

pp. 6-11

Author(s):

Leonardo Tondo ◽

Ross J. Baldessarini ◽

John Hennen

Keyword(s):

Suicide Risk ◽

Suicide Attempts ◽

Bipolar Depression ◽

Close Association ◽

Bipolar Disorders ◽

Term Treatment ◽

Diagnosis And Treatment ◽

Timely Diagnosis ◽

Long Term Treatment

AbstractCan timely diagnosis and treatment of depression reduce the risk of suicide? Studies of treatment effects on mortality in major mood disorders remain rare and are widely considered difficult to carry out ethically. Despite close associations of suicide with major affective disorders and related comorbidity, the available evidence provides little support for sustained reductions of suicide risk by most mood-altering treatments, including antidepressants. Studies designed to evaluate clinical benefits of mood-stabilizing treatments in bipolar disorders, however, provide comparisons of suicidal rates with and without treatment or under different treatment conditions. This emerging body of research provides consistent evidence of reduced rates of suicides and attempts during long-term treatment with lithium. This effect may not generalize to proposed alternatives, particularly carbamazepine. Our recent international collaborative studies found compelling evidence for prolonged reduction of suicidal risks during treatment with lithium, as well as sharp increases soon after its discontinuation, all in close association with depressive recurrences. Depression was markedly reduced, and suicide attempts were less frequent, when lithium was discontinued gradually. These findings indicate that studies of the effects of long-term treatment on suicide risk are feasible and that more timely diagnosis and treatment for all forms of major depression, but particularly for bipolar depression, should further reduce suicide risk.

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