scholarly journals ANALYSIS OF THE DIAGNOSTIC VALUE OF MAGNETIC RESONANCE COMPUTER TOMOGRAPHY AND POSITRON EMISSION COMPUTER TOMOGRAPHY WITH 18F-FDG IN IDENTIFICATION OF SPINAL AND PELVIC BONE METASTASES

2021 ◽  
Vol 20 (5) ◽  
pp. 100-107
Author(s):  
A. V. Laryukov ◽  
R. Sh. Hasanov ◽  
Z. A. Afanasyeva ◽  
E. K. Laryukova
Keyword(s):  
Magnetic Resonance ◽  
Bone Metastases ◽  
Diagnostic Value ◽  
Diagnostic Techniques ◽  
Pelvic Bone ◽  
Emission Computed Tomography ◽  
Resonance Imaging ◽  
Positron Emission ◽  
Pet Ct ◽  
Positron Emission Computed Tomography

Background. The treatment outcomes for non-small cell lung cancer (NSCLC) depend on the tumor stage and treatment strategy. The imaging techniques play a significant role in the diagnosis, staging and choice of appropriate treatment for NSCLC.Purpose of the study: сomparison of the diagnostic capabilities of magnetic resonance imaging (MR) and positron emission computed tomography to select the optimal approaches to early detection of spinal and pelvic bone metastases.Material and Methods. The treatment outcomes were analyzed in 71 patients with NSCLC. Spinal and pelvic bone metastases were detected in 24 patients using magnetic resonance imaging (MRI) and positron emission computed tomography (PET/CT). Multiple bone lesions were the most common. A total of 69 metastatic lesions were identified. To compare the capabilities of diagnostic techniques, all patients underwent PET/CT with 18F-FDG, and MRI of the spine and pelvic bones using diffused-weighted images (DWI). Statistical data processing included the calculation of the sensitivity, specificity and diagnostic accuracy of the above techniques.Conclusion. The comparative analysis of the capabilities of modern high-tech diagnostic techniques (PET/CT with 18F-FDG and MRI of the spine and pelvic bones with DWI) in early detection of bone metastases in patients with NSCLC, PET/CT with 18F-FDG showed the greatest diagnostic value. However, taking into account the high sensitivity and specificity of MRI with DVI in detection of bone metastases and limited availability of PET/CT for patients, MRI with DVI is recommended to exclude bone metastases. 

scholarly journals Diagnostic Value of Nineteen Different Imaging Methods for Patients with Breast Cancer: a Network Meta-Analysis

2018 ◽  
Vol 46 (5) ◽  
pp. 2041-2055 ◽  
Author(s):  
Xiao-Hong Zhang ◽  
Can Xiao
Keyword(s):  
Magnetic Resonance ◽  
Fdg Pet ◽  
Meta Analysis ◽  
Diagnostic Value ◽  
Ultrasound Elastography ◽  
Resonance Imaging ◽  
Imaging Methods ◽  
Positron Emission ◽  
Pet Ct ◽  
Fdg Pet Ct

Background/Aims: We performed a network meta-analysis (NMA) to investigate and compare the diagnostic value of 19 different imaging methods used for breast cancer (BC). Methods: Cochrane Library, PubMed and EMBASE were searched to collect the relevant literature from the inception of the study until November 2016. A combination of direct and indirect comparisons was performed using an NMA to evaluate the combined odd ratios (OR) and draw the surface under the cumulative ranking curves (SUCRA) of the diagnostic value of different imaging methods for BC. Results: A total of 39 eligible diagnostic tests regarding 19 imaging methods (mammography [MG], breast-specific gamma imaging [BSGI], color Doppler sonography [CD], contrast-enhanced magnetic resonance imaging [CE-MRI], digital breast tomosynthesis [DBT], fluorodeoxyglucose positron-emission tomography/computed tomography [FDG PET/CT], fluorodeoxyglucose positron-emission tomography [FDG-PET], full field digital mammography [FFDM], handheld breast ultrasound [HHUS], magnetic resonance imaging [MRI], automated breast volume scanner [ABUS], magnetic resonance mammography [MRM], scintimammography [SMM], single photon emission computed tomography scintimammography [SPECT SMM], ultrasound elastography [UE], ultrasonography [US], mammography + ultrasonography [MG + US], mammography + scintimammography [MG + SMM], and ultrasound elastography + ultrasonography [UE + US]) were included in the study. According to this network meta-analysis, in comparison to the MG method, the CE-MRI, MRI, MRM, MG + SMM and UE + US methods exhibited relatively higher sensitivity, and the specificity of the FDG PET/CT method was higher, while the BSGI and MRI methods exhibited higher accuracy. Conclusion: The results from this NMA indicate that the diagnostic value of the BSGI, MG + SMM, MRI and CE-MRI methods for BC were relatively higher in terms of sensitivity, specificity and accuracy.

scholarly journals Imaging Diagnosis of a Shoulder Tumor – Case Presentation

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 39
Author(s):  
R. Turcu ◽  
A. Barbilian
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Imaging Techniques ◽  
Emission Computed Tomography ◽  
Resonance Imaging ◽  
Slow Increase ◽  
Tumor Pathology ◽  
Positron Emission ◽  
Patient Will

Abstract Introduction. The most common and used molecular imaging techniques used in tumor pathology are the following: optics such as fluoroscopy, bioluminescence, and spectroscopy, radionuclides such as positron emission computed tomography, magnetic resonance with or without contrast substance, ultrasound and computed tomography. Material and method. A 39-year-old male patient accused having a shoulder tumor beginning 6 months before with a slow increase in volume without symptoms, pain, local temperature changes, and neurological phenomena. The clinical examination revealed the presence of an elastic consistency tumor, adherent to the bone but movable in soft adjacent tissues, without spontaneous and palpation pain, and local swelling. There was a slight functional embarrassment in conducting the abduction maneuver, but without limiting the amplitude of the movement. Results. Radiography of the shoulder did not reveal any significant changes. Magnetic resonance imaging of the shoulder and contrast-enhanced magnetic resonance imaging of the shoulder were performed. The evoked changes required a computed tomography of the shoulder. Conclusion. The thorough analysis of the imaging investigations and the clinical, paraclinical, and biological context of the patient will lead to the indication of the treatment and the optimal surgical time.

scholarly journals F-18 fluorodeoxyglucose positron emission computed tomography in the diagnosis of pleural metastases from breast carcinoma

2020 ◽  
Vol 7 (3) ◽  
pp. 764
Author(s):  
Murat Saricam
Keyword(s):  
Breast Cancer ◽  
Computed Tomography ◽  
Pleural Effusion ◽  
Emission Computed Tomography ◽  
Pleural Effusions ◽  
Fdg Uptake ◽  
Positron Emission ◽  
Pet Ct ◽  
Positron Emission Computed Tomography ◽  
Pleural Metastases

Background: This study aimed to investigate the feasibility of F-18 fluorodeoxyglucose (FDG) positron emission computed tomography (PET/CT) in identifying the pleural invasion of metastatic breast cancers.Methods: A retrospective study was conducted to include 75 patients with untreated breast cancer who had undergone thoracoscopy to drain pleural effusions and to perform pleural biopsies. Whole group of patients were evaluated in terms of age, type of primary breast cancer, macroscopic appearance of pleura during thoracoscopy, maximum standardized FDG uptake value (SUV) reported by PET/CT scan in addition to presence of malignancy detected in pleura and/or pleural effusion.Results: All of 75 patients were female and mean age was 56.12±11.70. Metastatic disease was diagnosed in the pleura of 40 (53.3%) and in the pleural effusion of 43 (57.3%) patients. The sensitivity and specificity of PET/CT in detecting pleural metastases of breast carcinoma was calculated as 88.2% and 96.2% whereas PET/CT demonstrated sensitivity of 91.9% and specificity of 91.3% in identifying malignant pleural effusion. Cut-off values of FDG uptake were 4.25 for pleural metastases and 3.85 for malignant pleural effusions. PET/CT also indicated a false negative rate of 12.5%, a false positive rate of 16.28% and an overall accuracy rate of 85.33% in the diagnosis of pleural metastasis of breast carcinoma.Conclusions: PET/CT reporting an FDG uptake over 4 in the pleura or pleural effusion is beneficial in managing the patients with the suspicion of pleural metastases from breast cancer.

Malignancy in non-HIV infected patients with cryptococcal meningitis: a retrospective study

2020 ◽  
Author(s):  
Xiaofeng Xu ◽  
Liping Cao ◽  
Yijie Wang ◽  
Jia Liu ◽  
Qing Dong ◽  
...  
Keyword(s):  
Cryptococcal Meningitis ◽  
Clinical Characteristics ◽  
Emission Computed Tomography ◽  
Positron Emission ◽  
Therapeutic Outcomes ◽  
Solid Malignancies ◽  
Pet Ct ◽  
Immunodeficiency Virus ◽  
Positron Emission Computed Tomography ◽  
Increase Rate

Abstract Background: Cryptococcal meningitis (CM) was found to be coexist with malignancy in non-human immunodeficiency virus (HIV) infected patients. The purpose of this study was to evaluate the clinical characteristics and therapeutic outcomes of CM in non-HIV infected patients with malignancy.Methods: A total of 320 CM patients were enrolled for analysis from January 2013-May 2019. One hundred and four patients underwent positron emission computed tomography (PET-CT) examination. The demographics, clinical characteristics, microbiological, radiological, therapeutic outcomes were analyzed in CM patients with and without malignancy.Results: Twelve patients with malignancy were found, of which 7 malignancy before CM (MBC), 5 malignancy after CM (MAC). CM patients with malignancy were older than non-malignancy ones. The prognosis of MBC patients was comparable to that of non-malignancy patients, but was extremely poor in MAC patients. Four out of 5 CM patients, who was suggested diagnosis as malignancy by PET-CT, were finally confirmed.Conclusions: This study found an increase rate of solid malignancies in CM patients. Screening malignancy in older CM patients was very important because it is closely related to prognosis and might affect treatment strategy. PET-CT might be a useful tool for early malignancy screening in CM.

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