INTERACTION OF CYTOCHROME P450 AND MICROSOMAL EPOXIDE HYDROLASE AND UDP-GLUCURONOSYLTRANSFERASE

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.16.supplement_94 ◽

2001 ◽

Vol 16 (supplement) ◽

pp. 94-95

Author(s):

Ken-ichiro TAURA ◽

Hideyuki YAMADA ◽

Eri NAITO ◽

Shuso TAKEDA ◽

Yuji ISHII ◽

...

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Microsomal Epoxide Hydrolase ◽

Udp Glucuronosyltransferase

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Interaction between Cytochrome P450 and Other Drug-Metabolizing Enzymes: Evidence for an Association of CYP1A1 with Microsomal Epoxide Hydrolase and UDP-Glucuronosyltransferase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2000.3076 ◽

2000 ◽

Vol 273 (3) ◽

pp. 1048-1052 ◽

Author(s):

Ken-ichiro Taura ◽

Hideyuki Yamada ◽

Yukiko Hagino ◽

Yuji Ishii ◽

Masa-aki Mori ◽

...

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Microsomal Epoxide Hydrolase ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes ◽

Udp Glucuronosyltransferase

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Evaluation of Octamethylcyclotetrasiloxane (D4) as an Inducer of Rat Hepatic Microsomal Cytochrome P450, UDP-Glucuronosyltransferase, and Epoxide Hydrolase: A 28-Day Inhalation Study

Toxicological Sciences ◽

10.1006/toxs.1997.2398 ◽

1998 ◽

Vol 41 (1) ◽

pp. 29-41 ◽

Author(s):

J McKim

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Inhalation Study ◽

Microsomal Cytochrome ◽

Microsomal Cytochrome P450 ◽

Udp Glucuronosyltransferase

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Differential induction of rat hepatic microsomal epoxide hydrolase and rGSTA2 by diazines: the role of cytochrome P450 2E1-mediated metabolic activation

Chemico-Biological Interactions ◽

10.1016/s0009-2797(98)00093-3 ◽

1998 ◽

Vol 116 (3) ◽

pp. 229-245 ◽

Author(s):

Min Kyung Cho ◽

Sang Geon Kim

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Metabolic Activation ◽

Microsomal Epoxide Hydrolase ◽

Cytochrome P450 2E1 ◽

Differential Induction

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Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes

Carcinogenesis ◽

10.1093/carcin/16.6.1391 ◽

1995 ◽

Vol 16 (6) ◽

pp. 1391-1401 ◽

Author(s):

Federico M. Farin ◽

Lenora G. Bigler ◽

Dolphine Oda ◽

James K. McDougall ◽

Curtis J. Omiecinski

Keyword(s):

Cytochrome P450 ◽

Human Papillomavirus ◽

Epithelial Cells ◽

Epoxide Hydrolase ◽

Microsomal Epoxide Hydrolase ◽

Human Papillomavirus Type 16 ◽

Oral Epithelial Cells ◽

Oral Epithelial

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Fingerprinting of Cytochrome P450 and Microsomal Epoxide Hydrolase Gene Expression in Human Blood Cells

Toxicological Sciences ◽

10.1093/toxsci/55.2.352 ◽

2000 ◽

Vol 55 (2) ◽

pp. 352-360 ◽

Author(s):

B. C. Krovat

Keyword(s):

Gene Expression ◽

Cytochrome P450 ◽

Human Blood ◽

Blood Cells ◽

Epoxide Hydrolase ◽

Microsomal Epoxide Hydrolase ◽

Human Blood Cells

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Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase

Carcinogenesis ◽

10.1093/carcin/5.8.993 ◽

1984 ◽

Vol 5 (8) ◽

pp. 993-1001 ◽

Author(s):

C.R. Wolf ◽

E. Moll ◽

T. Friedberg ◽

F. Oesch ◽

A. Buchmann ◽

...

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Glutathione Transferases ◽

Microsomal Epoxide Hydrolase ◽

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Selective induction of rat liver phase II enzymes by N-heterocycle analogues of phenanthrene: a response exhibiting high correlation between UDP-glucuronosyltransferase and microsomal epoxide hydrolase activities

Xenobiotica ◽

10.3109/00498259309059380 ◽

1993 ◽

Vol 23 (3) ◽

pp. 267-277 ◽

Author(s):

M. R. Franklin ◽

M. H. Slawson ◽

D. E. Moody

Keyword(s):

Rat Liver ◽

Phase Ii ◽

Epoxide Hydrolase ◽

Microsomal Epoxide Hydrolase ◽

Phase Ii Enzymes ◽

Udp Glucuronosyltransferase

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Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9

Clinical Pharmacology & Therapeutics ◽

10.1016/j.clpt.2005.01.010 ◽

2005 ◽

Vol 77 (5) ◽

pp. 365-372 ◽

Author(s):

R LOEBSTEIN ◽

M VECSLER ◽

D KURNIK ◽

N AUSTERWEIL ◽

E GAK ◽

...

Keyword(s):

Cytochrome P450 ◽

Genetic Variants ◽

Epoxide Hydrolase ◽

Warfarin Dose ◽

Microsomal Epoxide Hydrolase ◽

Cytochrome P450 2C9 ◽

Common Genetic Variants

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Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India

Archives of Toxicology ◽

10.1007/s00204-007-0276-4 ◽

2008 ◽

Vol 82 (9) ◽

pp. 633-639 ◽

Author(s):

Daya Shankar Srivastava ◽

Anil Mandhani ◽

Rama Devi Mittal

Keyword(s):

Bladder Cancer ◽

Cytochrome P450 ◽

Genetic Polymorphisms ◽

Epoxide Hydrolase ◽

North India ◽

Gene Interactions ◽

Microsomal Epoxide Hydrolase

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Evaluation of Octamethylcyclotetrasiloxane (D4) as an Inducer of Rat Hepatic Microsomal Cytochrome P450, UDP-Glucuronosyltransferase, and Epoxide Hydrolase: A 28-Day Inhalation Study

Toxicological Sciences ◽

10.1093/toxsci/41.1.29 ◽

1998 ◽

Vol 41 (1) ◽

pp. 29-41 ◽

Author(s):

James M. McKim ◽

Paul C. wilga ◽

Gary B. Kolesar ◽

Supratim Choudhuri ◽

Ajay Madan ◽

...

Keyword(s):

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Inhalation Study ◽

Microsomal Cytochrome ◽

Microsomal Cytochrome P450 ◽

Udp Glucuronosyltransferase

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