Non-Occupational HIV Post-Exposure Prophylaxis Among Men Who Have Sex with Men: A Systematic Review and Meta-Analysis of Global Data

2019 ◽  
Author(s):  
Zhenyu Wang ◽  
Tanwei Yuan ◽  
Song Fan ◽  
Hanzhu Qian ◽  
Peiyang Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
Global Data

scholarly journals Awareness and Use of Post-exposure Prophylaxis for HIV Prevention Among Men Who Have Sex With Men: A Systematic Review and Meta-Analysis

2022 ◽  
Vol 8 ◽  
Author(s):  
Junyan Jin ◽  
Runsong Sun ◽  
Tingting Mu ◽  
Taiyi Jiang ◽  
Lili Dai ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hiv Prevention ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Structural Barriers ◽  
Post Exposure ◽  
At Risk Populations ◽  
Sex With Men ◽  
Exposure Prophylaxis ◽  
Over Time

Background: The use of post-exposure prophylaxis (PEP) is effective in reducing HIV risk, but it is underused by men who have sex with men (MSM) due to certain psychological and sociostructural factors. This article assessed the awareness and use of PEP among MSM in an effort to increase the visibility and uptake of PEP among at-risk populations.Methods: We conducted a systematic literature search of the PubMed, Web of Science, PsycINFO, and Google Scholar electronic databases. Studies were screened for inclusion, and relevant data were abstracted, assessed for bias, and synthesized. Pooled effect estimates were calculated using random effects meta-analysis, meta-regression and subgroup analysis, and a qualitative review and risk of bias assessment were performed (PROSPERO, CRD42019123815).Results: Twenty eligible studies involving 12,579 MSM were included in the meta-analysis. The pooled estimate of the proportions of MSM who were aware of PEP was modest at 59.9% (95% CI: 50.5~68.7) and that of MSM who previously used PEP was very low at 4.9% (95% CI: 2.4~9.8). PEP awareness showed no clear change over time, while PEP use significantly changed over time. Multiple factors affected awareness, including educational attainment, race/ethnicity, levels of HIV stigma, access to condoms, and so on. Many factors could potentially impede or facilitate the use of PEP, such as income, lack of PEP information, and partnership.Conclusion: We observed that PEP is an underused HIV prevention strategy among MSM and that once MSM become aware of PEP, the majority are willing to use it if they are supported appropriately in terms of a range of individual, social, and structural barriers.Systematic Review Registration: http://www.cdr.york.ac.uk/prospero, PROSPERO [CRD42019123815].

scholarly journals Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.

2021 ◽  
pp. 100062
Author(s):  
Paulo Ricardo Martins-Filho ◽  
Lis Campos Ferreira ◽  
Luana Heimfarth ◽  
Adriano Antunes de Souza Araújo ◽  
Lucindo José Quintans-Júnior
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Efficacy And Safety ◽  
Post Exposure ◽  
Exposure Prophylaxis

scholarly journals Adherence to HIV post-exposure prophylaxis in victims of sexual assault: a systematic review and meta-analysis

2012 ◽  
Vol 88 (5) ◽  
pp. 335-341 ◽  
Author(s):  
Liza Chacko ◽  
Nathan Ford ◽  
Mariam Sbaiti ◽  
Ruby Siddiqui
Keyword(s):  
Systematic Review ◽  
Sexual Assault ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis

scholarly journals Adherence to Post-Exposure Prophylaxis for Non-forcible Sexual Exposure to HIV: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 18 (2) ◽  
pp. 217-225 ◽  
Author(s):  
Catherine E. Oldenburg ◽  
Till Bärnighausen ◽  
Guy Harling ◽  
Matthew J. Mimiaga ◽  
Kenneth H. Mayer
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis

scholarly journals P030 HIV post-exposure prophylaxis to pre-exposure prophylaxis transitioning in men who have sex with men

2021 ◽  
Author(s):  
D Richardson ◽  
K Nichols ◽  
A Pickering ◽  
J Devlin ◽  
Z Buss ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals P11.27 Does accessing non-occupational post exposure prophylaxis and the associated clinical experience impact condom use among men who have sex with men in victoria, australia

2015 ◽  
Vol 91 (Suppl 2) ◽  
pp. A183-A183
Author(s):  
Anna L Wilkinson ◽  
Anna B Pierce ◽  
Carol El-Hayek ◽  
Damien McCarthy ◽  
Jude Armishaw ◽  
...  
Keyword(s):  
Condom Use ◽  
Clinical Experience ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals Post-exposure prophylaxis vaccination rate and risk factors of human rabies in mainland China: a meta-analysis

2018 ◽  
Vol 147 ◽  
Author(s):  
D. L. Wang ◽  
X. F. Zhang ◽  
H. Jin ◽  
X. Q. Cheng ◽  
C. X. Duan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rural Areas ◽  
Meta Analysis ◽  
Mainland China ◽  
Vaccination Rate ◽  
Human Rabies ◽  
Post Exposure Prophylaxis ◽  
Eastern Region ◽  
Post Exposure ◽  
Exposure Prophylaxis

AbstractRabies is one of the major public health problems in China, and the mortality rate of rabies remains the highest among all notifiable infectious diseases. A meta-analysis was conducted to investigate the post-exposure prophylaxis (PEP) vaccination rate and risk factors for human rabies in mainland China. The PubMed, Web of Science, Chinese National Knowledge Infrastructure, Chinese Science and Technology Periodical and Wanfang databases were searched for articles on rabies vaccination status (published between 2007 and 2017). In total, 10 174 human rabies cases from 136 studies were included in this meta-analysis. Approximately 97.2% (95% confidence interval (CI) 95.1–98.7%) of rabies cases occurred in rural areas and 72.6% (95% CI 70.0–75.1%) occurred in farmers. Overall, the vaccination rate in the reported human rabies cases was 15.4% (95% CI 13.7–17.4%). However, among vaccinated individuals, 85.5% (95% CI 79.8%–83.4%) did not complete the vaccination regimen. In a subgroup analysis, the PEP vaccination rate in the eastern region (18.8%, 95% CI 15.9–22.1%) was higher than that in the western region (13.3%, 95% CI 11.1–15.8%) and this rate decreased after 2007. Approximately 68.9% (95% CI 63.6–73.8%) of rabies cases experienced category-III exposures, but their PEP vaccination rate was 27.0% (95% CI 14.4–44.9%) and only 6.1% (95% CI 4.4–8.4%) received rabies immunoglobulin. Together, these results suggested that the PEP vaccination rate among human rabies cases was low in mainland China. Therefore, standardised treatment and vaccination programs of dog bites need to be further strengthened, particularly in rural areas.

scholarly journals Effects of Pre-exposure Prophylaxis for the Prevention of Human Immunodeficiency Virus Infection on Sexual Risk Behavior in Men Who Have Sex With Men: A Systematic Review and Meta-analysis

2018 ◽  
Vol 67 (5) ◽  
pp. 676-686 ◽  
Author(s):  
Michael W Traeger ◽  
Sophia E Schroeder ◽  
Edwina J Wright ◽  
Margaret E Hellard ◽  
Vincent J Cornelisse ◽  
...  
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Virus Infection ◽  
Human Immunodeficiency Virus Infection ◽  
Risk Behavior ◽  
Sexual Risk ◽  
Meta Analysis ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Exposure Prophylaxis

scholarly journals High Interest in Syphilis Pre-exposure and Post-exposure Prophylaxis Among Gay, Bisexual and Other Men Who Have Sex With Men in Vancouver and Toronto

2020 ◽  
Vol 47 (4) ◽  
pp. 224-231 ◽  
Author(s):  
Laura Fusca ◽  
Mark Hull ◽  
Patrick Ross ◽  
Troy Grennan ◽  
Ann N. Burchell ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
High Interest ◽  
Sex With Men ◽  
Exposure Prophylaxis
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