Beyond Low-Earth Orbit: Characterizing the Immune Profile Following Simulated Spaceflight Conditions for Deep Space Missions

2020 ◽  
Author(s):  
Amber M. Paul ◽  
Margareth Cheng-Campbell ◽  
Elizabeth A. Blaber ◽  
Sulekha Anand ◽  
Sharmila Bhattacharya ◽  
...  

Author(s):  
Pantelis-Daniel Arapoglou ◽  
Massimo Bertinelli ◽  
Paolo Concari ◽  
Alberto Ginesi ◽  
Marco Lanucara


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
J. N. Chung ◽  
Jun Dong ◽  
Hao Wang ◽  
S. R. Darr ◽  
J. W. Hartwig

AbstractThe extension of human space exploration from a low earth orbit to a high earth orbit, then to Moon, Mars, and possibly asteroids is NASA’s biggest challenge for the new millennium. Integral to this mission is the effective, sufficient, and reliable supply of cryogenic propellant fluids. Therefore, highly energy-efficient thermal-fluid management breakthrough concepts to conserve and minimize the cryogen consumption have become the focus of research and development, especially for the deep space mission to mars. Here we introduce such a concept and demonstrate its feasibility in parabolic flights under a simulated space microgravity condition. We show that by coating the inner surface of a cryogenic propellant transfer pipe with low-thermal conductivity microfilms, the quenching efficiency can be increased up to 176% over that of the traditional bare-surface pipe for the thermal management process of chilling down the transfer pipe. To put this into proper perspective, the much higher efficiency translates into a 65% savings in propellant consumption.









2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Desirè Pantalone ◽  
Giulia Satu Faini ◽  
Francesca Cialdai ◽  
Elettra Sereni ◽  
Stefano Bacci ◽  
...  

AbstractThe target of human flight in space has changed from permanence on the International Space Station to missions beyond low earth orbit and the Lunar Gateway for deep space exploration and Missions to Mars. Several conditions affecting space missions had to be considered: for example the effect of weightlessness and radiations on the human body, behavioral health decrements or communication latency, and consumable resupply. Telemedicine and telerobotic applications, robot-assisted surgery with some hints on experimental surgical procedures carried out in previous missions, had to be considered as well. The need for greater crew autonomy in health issues is related to the increasing severity of medical and surgical interventions that could occur in these missions, and the presence of a highly trained surgeon on board would be recommended. A surgical robot could be a valuable aid but only inasfar as it is provided with multiple functions, including the capability to perform certain procedures autonomously. Space missions in deep space or on other planets present new challenges for crew health. Providing a multi-function surgical robot is the new frontier. Research in this field shall be paving the way for the development of new structured plans for human health in space, as well as providing new suggestions for clinical applications on Earth.



2020 ◽  
Vol 49 (1_suppl) ◽  
pp. 193-193
Author(s):  
U. Straube

Yuri Gagarin was the first human in space in 1961 almost 60 years ago. Eight years later Neil Armstrong left his footprints on the Moon – the first human on the surface of a celestial body other than Earth. By now long-duration missions of up to 1 year have become a reality for humans in space. Nearly 19 years of continuous human presence at the International Space Station (ISS) have provided a unique insight into human life in space. Humans are reaching out for more – targeting missions to take us outside the protective hull of low earth orbit into deep space. The challenges to human health and well-being remain significant and increase with distance and time from Earth. The lack of gravity, the ubiquitous ionising radiation, remoteness, and confinement are just some examples of the hostile environment of space. More hurdles have to be overcome prior to the human endeavour of reaching out into deep space and radiation is one such primary and inevitable factor that is key to crew health, safety and overall mission success. This presentation will provide an introduction into operational space medicine and radiation protection for humans in space as executed on ISS, in low earth orbit and in preparation for the scenarios ‘beyond’.





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