scholarly journals Neuroepithelial Organoid Patterning is Mediated by Wnt-Driven Turing Mechanism

2021 ◽  
Author(s):  
Abdel Rahman Abdel Fattah ◽  
Sergei Grebeniuk ◽  
Laura PMH de Rooij ◽  
Idris Salmon ◽  
Suresh Poovathingal ◽  
...  
Keyword(s):  

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Sayat Mimar ◽  
Mariamo Mussa Juane ◽  
Jorge Mira ◽  
Juyong Park ◽  
Alberto P. Muñuzuri ◽  
...  


Author(s):  
John Vandermeer ◽  
Ivette Perfecto


2010 ◽  
Vol 15 (6) ◽  
pp. 747-758 ◽  
Author(s):  
ANASTASIOS XEPAPADEAS

ABSTRACTMechanisms generating patterns in spatial domains have been extensively studied in biology, but also in economics in the context of new economic geography. The Turing mechanism or Turing diffusion-induced instability has been central to the understanding of forces which endogenously generate spatial patterns, but in a context where agents do not explicitly optimize an objective. The present paper reviews tools to study, in the spirit of Turing's analysis, a mechanism generating optimal diffusion-induced instability where optimizing agents generate optimal agglomerations. By extending the maximum principle to the optimal control of partial differential equations, it is shown how under certain conditions it will be optimal to design controls so that the price-quantity system implied by the costate–state functions of the optimal control of distributed parameter systems induces optimal spatial patterns. These methods might be useful in studying pattern formation both in problems of resource management and of economic development.





Author(s):  
Jakob Hartig ◽  
John Friesen ◽  
Peter F. Pelz

Worldwide, about one in eight people live in a slum. Empirical studies based on satellite data have identified that the size distributions of this type of settlement are similar in different cities of the Global South. Based on this result, a model was developed that describes the formation of slums with a Turing mechanism, in which patterns are created by diffusion-driven instability and the inherent characteristic length of the system is independent of boundary conditions. It has not yet been taken into account that Turing patterns usually arrange themselves regularly, while slums are often found in clusters. Therefore, this study investigates to what extent a common reaction kinetics for Turing models can be adapted to represent a locally concentrated arrangement of objects and to adapt the size distribution of the objects to the empirical results. Based on a summary of the literature and two numerical studies, it can be shown that although it is possible to adapt the model to the empirical data, this also increases the complexity of the model.



Author(s):  
C. Konow ◽  
M. Dolnik ◽  
I. R. Epstein

In 1952, Alan Turing proposed a theory showing how morphogenesis could occur from a simple two morphogen reaction–diffusion system [Turing, A. M. (1952) Phil. Trans. R. Soc. Lond. A 237 , 37–72. (doi:10.1098/rstb.1952.0012)]. While the model is simple, it has found diverse applications in fields such as biology, ecology, behavioural science, mathematics and chemistry. Chemistry in particular has made significant contributions to the study of Turing-type morphogenesis, providing multiple reproducible experimental methods to both predict and study new behaviours and dynamics generated in reaction–diffusion systems. In this review, we highlight the historical role chemistry has played in the study of the Turing mechanism, summarize the numerous insights chemical systems have yielded into both the dynamics and the morphological behaviour of Turing patterns, and suggest future directions for chemical studies into Turing-type morphogenesis. This article is part of the theme issue ‘Recent progress and open frontiers in Turing’s theory of morphogenesis’.



Life ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 58 ◽  
Author(s):  
Rinat Arbel-Goren ◽  
Francesca Di Patti ◽  
Duccio Fanelli ◽  
Joel Stavans

Under nitrogen-poor conditions, multicellular cyanobacteria such as Anabaena sp. PCC 7120 undergo a process of differentiation, forming nearly regular, developmental patterns of individual nitrogen-fixing cells, called heterocysts, interspersed between intervals of vegetative cells that carry out photosynthesis. Developmental pattern formation is mediated by morphogen species that can act as activators and inhibitors, some of which can diffuse along filaments. We survey the limitations of the classical, deterministic Turing mechanism that has been often invoked to explain pattern formation in these systems, and then, focusing on a simpler system governed by birth-death processes, we illustrate pedagogically a recently proposed paradigm that provides a much more robust description of pattern formation: stochastic Turing patterns. We emphasize the essential role that cell-to-cell differences in molecular numbers—caused by inevitable fluctuations in gene expression—play, the so called demographic noise, in seeding the formation of stochastic Turing patterns over a much larger region of parameter space, compared to their deterministic counterparts.





2015 ◽  
Vol 31 (2) ◽  
pp. 88-96 ◽  
Author(s):  
Masakatsu Watanabe ◽  
Shigeru Kondo
Keyword(s):  


2013 ◽  
Vol 10 (4) ◽  
pp. 046003 ◽  
Author(s):  
Denis Menshykau ◽  
Dagmar Iber


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