The Extended Geske Model and Its Consistency with Reduced Form Models

2005 ◽  
Author(s):  
Ren-Raw Chen ◽  
Ronald Sverdlove
Keyword(s):  
Reduced Form

Rabeprazole treatment increased the level of reduced form of glutathione and attenuated the H.pylori -associated gastric mucosal inflammation in mongolian gerbils

2001 ◽  
Vol 120 (5) ◽  
pp. A650-A650
Author(s):  
M MIYAZAWA ◽  
H SUZUKI ◽  
S NAGAHASHI ◽  
M SATO ◽  
M BESSHO ◽  
...  
Keyword(s):  
Reduced Form ◽  
Mucosal Inflammation ◽  
Mongolian Gerbils

Aerodynamic Shape Influence and Optimum Thickness Distribution Analysis of Perceptive Wind Turbine Blade

2018 ◽  
Vol 7 (3) ◽  
pp. 1
Author(s):  
J. V. Muruga Lal Jeyan ◽  
Akhila Rupesh ◽  
Jency Lal
Keyword(s):  
Wind Energy ◽  
Wind Turbine ◽  
Thickness Distribution ◽  
Turbine Blades ◽  
Reduced Form ◽  
Load Factor ◽  
Strong Impact ◽  
Theory Approach ◽  
Distribution Analysis ◽  
Optimum Thickness

The aerodynamic module combines the three-dimensional nonlinear lifting surface theory approach, which provides the effective propagated incident velocity and angle of attack at the blade section separately, and a two-dimensional panel method for steady axisymmetric and non-symmetric flow has to be involved to obtain the 3D pressure and velocity distribution on the wind mill model blade. Wind mill and turbines have become an economically competitive form of efficiency and renewable work generation. In the abroad analytical studies, the wind turbine blades to be the target of technological improvements by the use of highly possible systematic , aerodynamic and design, material analysis, fabrication and testing. Wind energy is a peculiar form of reduced form of density source of power. To make wind power feasible, it is important to optimize the efficiency of converting wind energy into productivity source. Among the different aspects involved, rotor aerodynamics is a key determinant for achieving this goal. There is a tradeoff between thin airfoil and structural efficiency. Both of which have a strong impact on the cost of work generated. Hence the design and analysis process for optimum design requires determining the load factor, pressure and velocity impact and optimum thickness distribution by finding the effect of blade shape by varying thickness on the basis of both the aerodynamic output and the structural weight.

Type 2 diabetes mellitus in patients with acute ischemiс stroke is associated with a decrease in plasma glutathione levels

2020 ◽  
Vol 25 (5) ◽  
pp. 29-35
Author(s):  
M. Yu. Maksimova ◽  
A. V. Ivanov ◽  
K. A. Nikiforova ◽  
F. R. Ochtova ◽  
E. T. Suanova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Redox Status ◽  
Reduced Form ◽  
Glutathione Level ◽  
Total Glutathione ◽  
Diabetes Mellitus Group ◽  
Reduced Forms

Ischemic stroke (IS) and type 2 diabetes mellitus are factors that affect the homeostasis of low-molecularweight aminothiols (cysteine, homocysteine, glutathione etc.). It has already been shown that IS in the acute period led to a decrease a level of reduced forms of aminothiols, but it is not clear whether type 2 diabetes mellitus has a noticeable effect there. Objective: to reveal the features of homeostasis of aminothiols in patients with type 2 diabetes mellitus in acute IS. Material and methods. The study involved 76 patients with primary middle cerebral artery IS in the first 10–24 hours after development of neurological symptoms. Group 1 included 15 patients with IS and type 2 diabetes mellitus, group 2 — 61 patients with IS and stress hyperglycemia. Their total plasma levels of cysteine, homocysteine, and glutathione, their reduced forms, and redox status were determined at admission (in the first 24 hours after IS). Results. There was a decrease in the level of total glutathione level (1.27 vs. 1.65 μM, p = 0.021), as well as its reduced form (0.03 vs. 0.04 μM, p = 0.007) in patients with IS and type 2 diabetes mellitus. Patients with type 2 diabetes mellitus who had a low redox status of homocysteine (0.65–1.2%) and glutathione (0.7–2.0%) were also characterized by a decrease in total glutathione level (p = 0.02; p = 0.03). Conclusion. Thus, type 2 diabetes mellitus is associated with a decrease in the level of total glutathione in acute IS. Probably, type 2 diabetes mellitus is characterized by a particular relationship between the metabolism of homocysteine, glutathione and glucose. Therefore, the search for homocysteine-dependent approaches to correct glutathione metabolism in type 2 diabetes mellitus may be of interest as an adjuvant therapy for IS.

The Logical Square and the Table of Oppositions

2012 ◽  
Vol 15 (1) ◽  
pp. 400-416
Author(s):  
Wolfgang Kienzler
Keyword(s):  
Reduced Form ◽  
Square Of Opposition ◽  
Logical Square ◽  
Long Time ◽  
The Square Of Opposition ◽  
The Way

The way Frege presented the Square of Opposition in a reduced form in 1879 and 1910 can be used to develop two distinct versions of the square: The traditional square that displays inferences and a “Table of Oppositions” displaying variations of negation. This Table of Oppositions can be further simplified and thus be made more symmetrical. A brief survey of versions of the square from Aristotle to the present shows how both aspects of the square have coexisted for a very long time without ever being properly distinguished.

Prevention of developing experіmental dіabetes by reduced form of glutathіone

2019 ◽  
Vol 95 (3) ◽  
pp. 21-27
Author(s):  
G.G. Meyramov ◽  
◽  
A.Zh. Shaybek ◽  
K.-D. Kohnert ◽  
G.T. Kartbayeva ◽  
...  
Keyword(s):  
Reduced Form

Reduced-Form Valuation of Callable Corporate Bonds: Theory and Evidence

2008 ◽  
Author(s):  
Robert A. Jarrow ◽  
Haitao Li ◽  
Sheen Liu ◽  
Chunchi Wu
Keyword(s):  
Corporate Bonds ◽  
Reduced Form

What Factors Affect Doctorss Hours Decisions: Comparing Structural Discrete Choice and Reduced-Form Approaches

2015 ◽  
Author(s):  
Guyonne R.J. Kalb ◽  
Daniel Kuehnle ◽  
Anthony Scott ◽  
Terence Chai Cheng ◽  
Sung-Hee Jeon
Keyword(s):  
Discrete Choice ◽  
Reduced Form

Electroanalytical chemistry of vanadium complexes: Electrochemical oxidation of [V(IV)O(nta)(H2O)]-

1989 ◽  
Vol 54 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Roland Meier ◽  
Gerhard Werner ◽  
Matthias Otto
Keyword(s):  
Cyclic Voltammetry ◽  
Electrochemical Oxidation ◽  
Ph Dependence ◽  
Differential Pulse ◽  
Nitrilotriacetic Acid ◽  
Reduced Form ◽  
Vanadium Complexes ◽  
Differential Pulse Polarography ◽  
Electroanalytical Chemistry ◽  
Ph Range

Electrochemical oxidation of [V(IV)O(nta)(H2O)]- (H3nta nitrilotriacetic acid) was studied in aqueous solution by means of cyclic voltammetry, differential pulse polarography, and current sampled DC polarography on mercury as electrode material. In the pH-range under study (5.5-9.0) the corresponding V(V) complex is produced by one-electron oxidation of the parent V(IV) species. The oxidation product is stable within the time scale of cyclic voltammetry. The evaluation of the pH-dependence of the half-wave potentials leads to a pKa value for [V(IV)O(nta)(H2O)]- which is in a good agreement with previous determinations. The measured value for E1/2 is very close to the formal potential E0 calculated via the Nernst equation on the basis of known literature values for log Kox and log Kred, the complex stability constants for the oxidized and reduced form, respectively.

Evidence for presence of a reduced form of digoxin-like immunoreactive factor (dihydro-DLIF) in mammalian tissues

1996 ◽  
Vol 42 (7) ◽  
pp. 1092-1099 ◽  
Author(s):  
H M Qazzaz ◽  
S A Jortani ◽  
J M Poole ◽  
R Valdes
Keyword(s):  
Lactone Ring ◽  
Fold Increase ◽  
Cross Reactivity ◽  
Reduced Form ◽  
Molar Ratio ◽  
Endogenous Ligand ◽  
Metabolic Route ◽  
Mammalian Tissues ◽  
Spectral Absorbance ◽  
Cytochrome P 450

Abstract Digoxin-like immunoreactive factor (DLIF) from adrenal glands is an endogenous ligand structurally related to the plant-derived cardiac glycoside digoxin. Cardiac glycosides regulate the activity of the sodium pump and thus play key roles in disease processes involving regulation of ion transport. We now report the discovery of an endogenous dihydro-DLIF analogous to dihydrodigoxin. We used HPLC, ultraviolet spectrophotometry, and cross-reactivity with two antibodies, one specific for digoxin and one for dihydrodigoxin, to support the hypothesis that dihydro-DLIF contains a chemically reduced lactone ring. The spectral absorbance maximum for dihydro-DLIF is at 196 nm, identical to dihydrodigoxin. DLIF and dihydro-DLIF are 975- and 2588-fold less immunoreactive than digoxin and dihydrodigoxin for their respective antibodies. The molar ratio of dihydro-DLIF to DLIF is approximately 5.3 in bovine adrenocortical tissue and approximately 0.38 in human serum. Dihydrodigoxin (reduced lactone ring) added to microsomes isolated from bovine adrenal cortex produced a 4.5-fold increase in digoxin-like immunoreactivity (oxidized lactone ring) after 3 h of incubation. The biotransformation is likely mediated by a cytochrome P-450 NADPH-dependent process. Our findings demonstrate the presence of a dihydro-DLIF in mammals and suggest a metabolic route for synthesis of endogenous DLIF in mammalian tissue.

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