scholarly journals mRNA Expression of Cytochrome P450 17αhydroxylase, Cytochrome P450 Aromatase, Anti-Müllerian Hormone, Estrogen Receptor α, and Androgen Receptor in Developing Gonads of Japanese Quail

2008 ◽  
Vol 45 (4) ◽  
pp. 298-302 ◽  
Author(s):  
Keigo Nakamura ◽  
Kazumoto Shibuya ◽  
Noboru Saito ◽  
Kiyoshi Shimada ◽  
Atsushi Ohshima ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Cytochrome P450 ◽  
Androgen Receptor ◽  
Mrna Expression ◽  
Japanese Quail ◽  
Estrogen Receptor Α ◽  
P450 Aromatase ◽  
Cytochrome P450 Aromatase

scholarly journals Effect of Estradiol and Nonylphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos

2002 ◽  
Vol 39 (4) ◽  
pp. 302-309 ◽  
Author(s):  
Masanori Sakimura ◽  
Akira Tsukada ◽  
Makoto Usami ◽  
Shozo Hanzawa ◽  
Noboru Saito ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Estrogen Receptors ◽  
Mrna Expression ◽  
Chicken Embryos ◽  
P450 Aromatase ◽  
Cytochrome P450 Aromatase

scholarly journals cDNA Cloning and mRNA Expression of Estrogen Receptor α in Japanese Quail

2003 ◽  
Vol 40 (2) ◽  
pp. 121-129 ◽  
Author(s):  
Kouhei Ichikawa ◽  
Ichiro Yamamoto ◽  
Akira Tsukada ◽  
Noboru Saito ◽  
Kiyoshi Shimada
Keyword(s):  
Estrogen Receptor ◽  
Mrna Expression ◽  
Cdna Cloning ◽  
Japanese Quail ◽  
Estrogen Receptor Α

scholarly journals Lead Reduces Messenger RNA and Protein Levels of Cytochrome P450 Aromatase and Estrogen Receptor β in Human Ovarian Granulosa Cells1

2003 ◽  
Vol 68 (6) ◽  
pp. 1982-1988 ◽  
Author(s):  
Crystel Taupeau ◽  
Joël Poupon ◽  
Dominique Treton ◽  
Aurélie Brosse ◽  
Yolande Richard ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Cytochrome P450 ◽  
Messenger Rna ◽  
Estrogen Receptor Β ◽  
P450 Aromatase ◽  
Protein Levels ◽  
Cytochrome P450 Aromatase

scholarly journals Sex Hormone Receptor Signaling in Bladder Cancer: A Potential Target for Enhancing the Efficacy of Conventional Non-Surgical Therapy

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1169
Author(s):  
Hiroki Ide ◽  
Hiroshi Miyamoto
Keyword(s):  
Bladder Cancer ◽  
Estrogen Receptor ◽  
Androgen Receptor ◽  
Surgical Therapy ◽  
Urothelial Cancer ◽  
Hormone Receptors ◽  
Estrogen Receptor Α ◽  
Vital Role ◽  
Sex Hormone ◽  
Sex Steroid Hormone

There have been critical problems in the non-surgical treatment for bladder cancer, especially residence to intravesical pharmacotherapy, including BCG immunotherapy, cisplatin-based chemotherapy, and radiotherapy. Recent preclinical and clinical evidence has suggested a vital role of sex steroid hormone-mediated signaling in the progression of urothelial cancer. Moreover, activation of the androgen receptor and estrogen receptor pathways has been implicated in modulating sensitivity to conventional non-surgical therapy for bladder cancer. This may indicate the possibility of anti-androgenic and anti-estrogenic drugs, apart from their direct anti-tumor activity, to function as sensitizers of such conventional treatment. This article summarizes available data suggesting the involvement of sex hormone receptors, such as androgen receptor, estrogen receptor-α, and estrogen receptor-β, in the progression of urothelial cancer, focusing on their modulation for the efficacy of conventional therapy, and discusses their potential of overcoming therapeutic resistance.

Sign in / Sign up

Export Citation Format

Share Document