scholarly journals Inflammatory Bowel Disease Epidemiology in São Paulo State, Brazil [Corrigendum]

2020 ◽  
Vol Volume 13 ◽  
pp. 221-222
Author(s):  
Rodrigo Galhardi Gasparini ◽  
Lígia Yukie Sassaki ◽  
Rogerio Saad-Hossne
2009 ◽  
Vol 46 (1) ◽  
pp. 20-25 ◽  
Author(s):  
Carlos Roberto Victoria ◽  
Ligia Yukie Sassak ◽  
Hélio Rubens de Carvalho Nunes

CONTEXT:The incidence and populational prevalence of inflammatory bowel diseases, hitherto unknown in Brazil, were estimated for a region in the Midwest of São Paulo State, Brazil. METHODS: Using a sequential registry of 115 adult patients (>15 years old) with inflammatory bowel diseases - exclusively residing in the studied region with 533,508 inhabitants (2005) and attended at the reference hospital during a 20 year interval (1986-2005) - were estimated, in four consecutives periods of 5 years each, the incidences according to gender, type of the disease and the prevalence of these diseases, and its inner-relations evaluated by the Poisson regression model. RESULTS: The inflammatory bowel diseases in the studied region predominated among young, white race and people living in urban area, and the incidence on the female population rose during this period. The incidence of ulcerative colitis were higher than Crohn's disease and non-classified colitis, and showed a progressive increase in the first three periods with a decrease in the last one (2001-2005), where the observed rates of ulcerative colitis, Crohn's disease and non-classified colitis were 4.48, 3.50 and 1.75 cases/100,000 inhabitants, with prevalence of 22.61, 14.81, 5.65, 2.14 cases/100,000 inhabitants for total inflammatory bowel diseases. CONCLUSION: The inflammatory bowel diseases incidence in the studied area was as low as in other countries of Latin America and smaller than that found in countries of South Europe. The crescent prevalence justifies the policies to adequate medical cares for inflammatory bowel diseases patients in this area.


2018 ◽  
Vol Volume 11 ◽  
pp. 423-429 ◽  
Author(s):  
Rodrigo Galhardi Gasparini ◽  
Lígia Yukie Sassaki ◽  
Rogerio Saad-Hossne

2021 ◽  
Vol Volume 14 ◽  
pp. 91-102
Author(s):  
Tarcia Nogueira Ferreira Gomes ◽  
Fabio Silva de Azevedo ◽  
Marjorie Argollo ◽  
Sender Jankiel Miszputen ◽  
Orlando Ambrogini JR

2021 ◽  
Vol 58 (4) ◽  
pp. 495-503
Author(s):  
Maraci RODRIGUES ◽  
Cleonice BUENO ◽  
Elizete Aparecida LOMAZI ◽  
Maria Inez Machado FERNANDES ◽  
Clarice Blaj NEUFELD ◽  
...  

ABSTRACT BACKGROUND: Perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) and anti-Saccharomyces cerevisiae antibodies (ASCAs) have long been used to differentiate between Crohn’s disease (CD) and ulcerative colitis (UC), more recently having been used as prognostic indicators. OBJECTIVE: To determine the diagnostic accuracy of serological markers in the identification of pediatric CD and UC in Sao Paulo, Brazil, as well as to correlate those markers with characteristics demographic and clinical of these two diseases. METHODS: Retrospective cross-sectional multi-center study involving pediatric patients with inflammatory bowel disease (IBD). We identified ASCAs serological markers and p-ANCA, correlating their presence with demographic and clinical data, not only in the patients with IBD but also in a group of age-matched gastrointestinal disease-free controls. RESULTS: A total of 122 patients, 74 with IBD (46% males), treated at four pediatric gastroenterology referral centers, the mean age of 13±7 years, 49 (66%) with CD, and 25 (34%) with UC. The control Group comprised 48 patients (54% males). The proportion of patients testing positive for p-ANCA was significantly higher in the UC group (69.9%) compared to the CD group (30.4%), as well as being significantly higher in the CD group versus the control Group (P<0.001 for both). The proportion of patients testing positive for ASCA IgA (76.2%) and ASCA IgG (94.4%) markers was also significantly higher in the CD group than in the control Group (P<0.001), and such positivity correlated significantly with the use of immunomodulatory medications such as azathioprine and anti-tumor necrosis factor agents (azathioprine 38.9%, anti-TNF 55.6%; P=0.002). In the CD group, the proportion of patients testing positive for the ASCA IgA was significantly higher among those who underwent surgery than among those who did not (26.86±17.99; P=0.032). CONCLUSION: In pediatric patients with IBD in Sao Paulo, Brazil, serological tests proving to be highly specific, although not very sensitive, for the diagnosis of IBD. However, the serological markers showed a positive correlation with the severity of the disease.


Author(s):  
Liliane Maria Guimarães de Pinho ◽  
Vera Lúcia Garcia ◽  
Maria Cezira Fantini Nogueira-Martins

Implementation of a multiprofessional residency in family health in a city of São Paulo state: perception of the first residents (2014-2016)


2017 ◽  
Vol 314 (3) ◽  
pp. 1675-1681
Author(s):  
Elvis J. França ◽  
Elisabete A. De Nadai Fernandes ◽  
Felipe Y. Fonseca ◽  
Marcelo R. L. Magalhães ◽  
Mariana L. O. Santos

Author(s):  
Raquel Cardoso de Souza ◽  
Aline Andrade Godoy ◽  
Fábio Kummrow ◽  
Thyago Leandro dos Santos ◽  
Carlos Jesus Brandão ◽  
...  

2021 ◽  
Vol 141 ◽  
pp. 110805
Author(s):  
Giancarlo Aquila ◽  
Wilson Toshiro Nakamura ◽  
Paulo Rotella Junior ◽  
Luiz Celio Souza Rocha ◽  
Edson de Oliveira Pamplona

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