scholarly journals Barrier effect of Esoxx® on esophageal mucosal damage: experimental study on ex-vivo swine model

2012 ◽  
pp. 103 ◽  
Author(s):  
Massimo Di Simone ◽  
Fabio Baldi ◽  
Valentina Vasina ◽  
Maria Laura Bacci ◽  
Fabrizio Scorrano ◽  
...  
Keyword(s):  
Experimental Study ◽  
Ex Vivo ◽  
Mucosal Damage ◽  
Swine Model ◽  
Barrier Effect

scholarly journals Barrier Effect of a New Topical Agent on Damaged Esophageal Mucosa: Experimental Study on an ex vivo Swine Model

2020 ◽  
Vol Volume 13 ◽  
pp. 569-576
Author(s):  
Roberta Salaroli ◽  
Domenico Ventrella ◽  
Chiara Bernardini ◽  
Alberto Elmi ◽  
Augusta Zannoni ◽  
...  
Keyword(s):  
Experimental Study ◽  
Ex Vivo ◽  
Swine Model ◽  
Esophageal Mucosa ◽  
Topical Agent ◽  
Barrier Effect

Transscleral optical coherence tomography?An experimental study in ex-vivo human eyes

2002 ◽  
Vol 30 (3) ◽  
pp. 209-215 ◽  
Author(s):  
Hans Hoerauf ◽  
J�rg Winkler ◽  
Christian Scholz ◽  
Christopher Wirbelauer ◽  
Roswitha S. Gordes ◽  
...  
Keyword(s):  
Experimental Study ◽  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Optical Coherence ◽  
Human Eyes

Effect of tibial tuberosity advancement on cranial tibial subluxation in the feline cranial cruciate deficient stifle joint: An ex vivo experimental study

2016 ◽  
Vol 107 ◽  
pp. 240-245 ◽  
Author(s):  
M. Retournard ◽  
A. Bilmont ◽  
E. Asimus ◽  
S. Palierne ◽  
A. Autefage
Keyword(s):  
Experimental Study ◽  
Ex Vivo ◽  
Tibial Tuberosity ◽  
Stifle Joint

scholarly journals Comparison of waveform-derived corneal stiffness and stress-strain extensometry-derived corneal stiffness using different cross-linking irradiances: an experimental study with air-puff applanation of ex vivo porcine eyes

2020 ◽  
Vol 258 (10) ◽  
pp. 2173-2184 ◽  
Author(s):  
Robert Herber ◽  
Mathew Francis ◽  
Eberhard Spoerl ◽  
Lutz E. Pillunat ◽  
Frederik Raiskup ◽  
...  
Keyword(s):  
Experimental Study ◽  
Ex Vivo ◽  
Cross Linking ◽  
Displacement Curve ◽  
Stress Strain ◽  
Strain Measurements ◽  
Deflection Amplitude ◽  
Force Displacement ◽  
Stiffening Effect ◽  
Porcine Eyes

Abstract Purpose To assess corneal stiffening of standard (S-CXL) and accelerated (A-CXL) cross-linking protocols by dynamic corneal response parameters and corneal bending stiffness (Kc[mean/linear]) derived from Corvis (CVS) Scheimpflug-based tonometry. These investigations were validated by corneal tensile stiffness (K[ts]), derived from stress-strain extensometry in ex vivo porcine eyes. Methods Seventy-two fresh-enucleated and de-epithelized porcine eyes were soaked in 0.1% riboflavin solution including 10% dextran for 10 min. The eyes were separated into four groups: controls (n = 18), S-CXL (intensity in mW/cm2*time in min; 3*30) (n = 18), A-CXL (9*10) (n = 18), and A-CXL (18*5) (n = 18), respectively. CXL was performed using CCL Vario. CVS measurements were performed on all eyes. Subsequently, corneal strips were extracted by a double-bladed scalpel and used for stress-strain measurements. K[ts] was calculated from a force-displacement curve. Mean corneal stiffness (Kc[mean]) and constant corneal stiffness (Kc[linear]) were calculated from raw CVS data. Results In CVS, biomechanical effects of cross-linking were shown to have a significantly decreased deflection amplitude as well as integrated radius, an increased IOP, and SP A1 (P < 0.05). Kc[mean]/Kc[linear] were significantly increased after CXL (P < 0.05). In the range from 2 to 6% strain, K[ts] was significantly higher in S-CXL (3*30) compared to A-CXL (9*10), A-CXL (18*5), and controls (P < 0.05). At 8% to 10% strain, all protocols induced a higher stiffness than controls (P < 0.05). Conclusion Several CVS parameters and Kc[mean] as well as Kc[linear] verify corneal stiffening effect after CXL on porcine eyes. S-CXL seems to have a higher tendency of stiffening than A-CXL protocols have, which was demonstrated by Scheimpflug-based tonometry and stress-strain extensometry.

Role of sensory afferents in the myoelectric response to acute enteric inflammation in the rabbit

1997 ◽  
Vol 273 (2) ◽  
pp. G447-G455 ◽  
Author(s):  
T. Shea-Donohue ◽  
J. M. Goldhill ◽  
E. Montcalm-Mazzilli ◽  
C. Colleton ◽  
V. M. Pineiro-Carrero ◽  
...  
Keyword(s):  
Neural Control ◽  
Ex Vivo ◽  
Neutrophil Infiltration ◽  
Mucosal Damage ◽  
Myoelectric Activity ◽  
Sensory Afferents ◽  
Rabbit Small Intestine ◽  
Sustained Inhibition

The role of sensory afferents in inflammation-induced alterations in myoelectric activity in vivo was investigated in the rabbit small intestine. Isolated ileal loops were implanted with serosal electrodes and exposed to ricin or vehicle after pretreatment with 125 mg/kg of subcutaneous (125 mg over 3 days) or intraluminal (640 microM) capsaicin. After 5 h of myoelectric recording, the loops were prepared for histology and for ex vivo generation of eicosanoids. Capsaicin exacerbated mucosal damage after exposure to ricin but did not alter neutrophil infiltration. Subcutaneous capsaicin alone elevated slow-wave frequency and spike events and transiently suppressed the myoelectric response to ricin. In contrast, intraluminal capsaicin alone did not alter myoelectric activity but produced a sustained inhibition of the response to ricin. Eicosanoid production was unchanged by capsaicin alone. Intraluminal capsaicin blocked increases in leukotriene C4 and prostaglandin E2 during inflammation, an effect that paralleled its inhibition of myoelectric activity. Thus the contribution of sensory afferents to altered motility during acute ileitis involves the release of mucosal inflammatory mediators that influence neural control of smooth muscle.

scholarly journals Thulium:YAG vs Holmium:YAG laser effect on soft tissue: Evidence from an ex vivo experimental study

2020 ◽  
Vol 19 ◽  
pp. e83-e84
Author(s):  
M.E. Rodríguez Socarrás ◽  
S. Proietti ◽  
R. Luciano’ ◽  
F. Scarfo’ ◽  
G. Saitta ◽  
...  
Keyword(s):  
Experimental Study ◽  
Soft Tissue ◽  
Ex Vivo ◽  
Holmium:Yag Laser ◽  
Laser Effect

Novel balloon catheter‐based endobiliary radiofrequency ablation system: Ex‐vivo experimental study

2020 ◽  
Vol 32 (6) ◽  
pp. 974-978 ◽  
Author(s):  
Tadahisa Inoue ◽  
Kiyoaki Ito ◽  
Masashi Yoneda
Keyword(s):  
Experimental Study ◽  
Radiofrequency Ablation ◽  
Ex Vivo ◽  
Balloon Catheter

scholarly journals Infusion of freshly isolated autologous bone marrow derived mononuclear cells prevents endotoxin-induced lung injury in an ex-vivo perfused swine model

2013 ◽  
Vol 4 (2) ◽  
pp. 26 ◽  
Author(s):  
Mauricio Rojas ◽  
Richard E Parker ◽  
Natalie Thorn ◽  
Claudia Corredor ◽  
Smita S Iyer ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Lung Injury ◽  
Mononuclear Cells ◽  
Ex Vivo ◽  
Autologous Bone Marrow ◽  
Swine Model ◽  
Autologous Bone
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