Successful application of extracorporeal membrane oxygenation due to pulmonary hemorrhage secondary to granulomatosis with polyangiitis

Abstract Background Pulmonary hemorrhage is an important complication of leptospirosis. Once acute respiratory distress syndrome (ARDS) occurs as a secondary condition, treatment is extremely difficult and the mortality rate is very high. Case presentation The patient was a 49-year-old. He was admitted to the hospital because he had experienced a fever and cough for 4 days. Hemorrhage, respiratory failure, ARDS and other symptoms appeared soon after admission. Due to severe pulmonary hemorrhage secondary to ARDS, mechanical ventilation was performed through tracheal intubation. During intubation, the patient suffered cardiac arrest, and the patient’s condition worsened. He was confirmed to have leptospirosis through second-generation sequencing of the alveolar lavage fluid. Finally, we successfully treated the patient with penicillin as an anti-infective medication and venous-venous extracorporeal membrane oxygenation (v-vECMO). To the best of our knowledge, this report is the first to describe the successful application of ECMO in mainland China. Conclusions Leptospirosis can induce serious but transient ARDS with a better prognosis than other causes of ARDS. Our patient was successfully treated with V-vECMO.

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Life-threatening antineutrophil cytoplasmic antibody–associated vasculitis after influenza A H1N1 infection requiring veno-venous extracorporeal membrane oxygenation

Perfusion ◽

10.1177/0267659120927210 ◽

2020 ◽

Vol 35 (6) ◽

pp. 546-549

Author(s):

Frantzeska G. Frantzeskaki ◽

Stavros Dimopoulos ◽

Dimitrios Konstantonis ◽

Pelagia Katsibri ◽

Kostantinos Kostopanagiotou ◽

...

Keyword(s):

Extracorporeal Membrane Oxygenation ◽

Influenza A ◽

Immunosuppressive Treatment ◽

Pulmonary Hemorrhage ◽

Antineutrophil Cytoplasmic Antibody ◽

H1n1 Infection ◽

Membrane Oxygenation ◽

Antineutrophil Cytoplasmic Autoantibody ◽

Influenza A H1n1 ◽

Life Threatening

Introduction: Antineutrophil cytoplasmic autoantibody–associated vasculitis is an immune-mediated necrotizing vasculitis, affecting small- and medium-sized vessels. Case report: A 22-year-old female patient with free medical history presented with life-threatening pulmonary hemorrhage due to antineutrophil cytoplasmic autoantibody–associated vasculitis, temporarily associated with influenza A H1N1 infection. Due to rapidly worsening respiratory failure, despite conventional management, veno-venous peripheral extracorporeal membrane oxygenation was initiated and continued for 26 days, with subsequent renal replacement therapy. Discussion: We present a case of severe antineutrophil cytoplasmic autoantibody–associated pulmonary vasculitis, managed with veno-venous extracorporeal membrane oxygenation at the initial phase. Despite the significant challenges raised with the use of extracorporeal membrane oxygenation in pulmonary hemorrhage cases, extracorporeal membrane oxygenation may have a significant impact on outcome in this setting, by providing adequate time for a successful immunosuppressive treatment.

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Extracorporeal Membrane Oxygenation as Salvage Treatment for Acute Respiratory Failure Secondary to Granulomatosis with Polyangiitis

10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1745 ◽

2019 ◽

Author(s):

K. Yin ◽

R. March ◽

J. Raman ◽

E. Bak ◽

K. Karlson ◽

...

Keyword(s):

Respiratory Failure ◽

Extracorporeal Membrane Oxygenation ◽

Acute Respiratory Failure ◽

Granulomatosis With Polyangiitis ◽

Salvage Treatment ◽

Membrane Oxygenation

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Survival after extreme left atrial hypertension and pulmonary hemorrhage in an infant supported with extracorporeal membrane oxygenation for refractory atrial flutter

Pediatric Critical Care Medicine ◽

10.1097/pcc.0b013e3181e8b3e5 ◽

2011 ◽

Vol 12 (3) ◽

pp. e149-e152 ◽

Cited By ~ 3

Author(s):

Michael J. Cisco ◽

Ritu Asija ◽

Anne M. Dubin ◽

Stanton B. Perry ◽

Frank L. Hanley ◽

...

Keyword(s):

Extracorporeal Membrane Oxygenation ◽

Atrial Flutter ◽

Left Atrial ◽

Pulmonary Hemorrhage ◽

Membrane Oxygenation

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Granulomatosis with polyangiitis presenting with diffuse alveolar hemorrhage requiring extracorporeal membrane oxygenation with rapid multiorgan relapse

Medicine ◽

10.1097/md.0000000000006024 ◽

2017 ◽

Vol 96 (13) ◽

pp. e6024 ◽

Cited By ~ 12

Author(s):

Jennifer Vanoli ◽

Marta Riva ◽

Beatrice Vergnano ◽

Gabriele D’Andrea ◽

Vincenzo L’Imperio ◽

...

Keyword(s):

Extracorporeal Membrane Oxygenation ◽

Granulomatosis With Polyangiitis ◽

Diffuse Alveolar Hemorrhage ◽

Alveolar Hemorrhage ◽

Membrane Oxygenation

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Extracorporeal membrane oxygenation for the control of a pulmonary artery hemorrhage

10.22541/au.162327697.74980481/v1 ◽

2021 ◽

Author(s):

Yuichiro Hirata ◽

Eiki Tayama ◽

Ryuya Nomura ◽

Tomofumi Fukuda ◽

Kojiro Furukawa ◽

...

Keyword(s):

Blood Flow ◽

Cardiac Surgery ◽

Cardiopulmonary Bypass ◽

Pulmonary Artery ◽

Extracorporeal Membrane Oxygenation ◽

Pulmonary Blood Flow ◽

Pulmonary Hemorrhage ◽

Massive Hemoptysis ◽

Membrane Oxygenation ◽

The Right

No standard treatments have been established for airway hemorrhage during cardiopulmonary bypass (CPB). Herein, we describe two cases of catheter-induced pulmonary hemorrhage during cardiac surgery. In each case, massive hemoptysis was observed during cardiopulmonary bypass (CPB) weaning. A bronchial blocker was inserted into the right bronchus, and extracorporeal membrane oxygenation (ECMO) was initiated to reduce pulmonary blood flow, and stabilize the hemodynamics. ECMO significantly reduced bleeding from the pulmonary artery (PA). Both cases had favorable outcomes following the implementation of extracorporeal membrane oxygenation (ECMO). ECMO is effective at controlling PA bleeding during and after cardiac surgery.

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