Medication Errors Among Hospitalized Adults in Medical Wards of Nekemte Specialized Hospital, West Ethiopia: A Prospective Observational Study

This case focuses on medication errors and adverse drug events occurring during the perioperative period by asking the question: What are the rates, types, severity, and preventability of medication errors (MEs) and adverse drug events (ADEs) in the perioperative setting during anesthesia care? This prospective observational study reported that approximately 1 in 20 perioperative medication administrations, and every second operation, resulted in an ME and/or an ADE. These rates are markedly higher than those reported by prior retrospective surveys. Process- and technology-based solutions may address the root causes of MEs to reduce their incidence.

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Current Practice and Barriers to an Early Antimicrobial Conversion from Intravenous to Oral among Hospitalized Patients at Jimma University Specialized Hospital: Prospective Observational Study

Interdisciplinary Perspectives on Infectious Diseases ◽

10.1155/2019/7847354 ◽

2019 ◽

Vol 2019 ◽

pp. 1-8

Author(s):

Alemseged Beyene Berha ◽

Gizat Molla Kassie

Keyword(s):

Observational Study ◽

Prospective Observational Study ◽

Current Practice ◽

Significant Proportion ◽

Severe Infection ◽

Hospitalized Patients ◽

P Values ◽

Specialized Hospital ◽

Jimma University ◽

Clinical Stability

Objective. The aim of the present study was to explore the current practice and its barriers to an early antimicrobial conversion from intravenous (IV) to oral (PO) therapy among hospitalized patients.Method. Hospital based prospective observational study was conducted to assess the practice of an early antimicrobial IV to PO conversion and its barriers using medical chart and case-specific physicians’ interviews, respectively, from February to September, 2014. Patient charts and medication records were reviewed for appropriateness of IV to PO conversion program every 24hrs using a pretested data collection abstraction format. Independent samplest-test was used to compare the duration of therapy and time to clinical stability between converted and nonconverted patients. Two-tailed P values of < 0.05 were regarded as statistically significant.Results. One hundred forty-two patients were included in the study, of whom two-thirds (67.6%) of the patients were eligible for IV to PO antimicrobial conversion. However, only 20.9% of patients’ timely conversion was made. A shorter duration of IV therapy was recorded for converted (2.80±1.87) versus nonconverted patients (8.50±6.32), (P=0.009). The most important barriers of not converting IV to PO in clinically stable patients were presence of comorbidity; clinicians perceived that the patient should always complete IV course of antimicrobials as a standard practice.Conclusion. Conversion from IV to PO antimicrobials was found to be unnecessarily delayed in a significant proportion of patients hospitalized with moderate to severe infection due to a range of different barriers. Addressing these issues has the potential to reduce inappropriate antimicrobial use and resistance.

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Prevalence and Factors Associated with Postoperative Pain After Cesarean Section at a Comprehensive Specialized Hospital in Northwest Ethiopia: Prospective Observational Study

Open Access Surgery ◽

10.2147/oas.s347920 ◽

2022 ◽

Vol Volume 15 ◽

pp. 1-8

Author(s):

Getamesay Demelash ◽

Yophtahe Woldegerima Berhe ◽

Amare Hailekiros Gebregzi ◽

Wubie Birlie Chekol

Keyword(s):

Postoperative Pain ◽

Observational Study ◽

Cesarean Section ◽

Prospective Observational Study ◽

Northwest Ethiopia ◽

Factors Associated ◽

Specialized Hospital

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Prospective observational study on the incidence of medication errors during simulated resuscitation in a paediatric emergency department

BMJ ◽

10.1136/bmj.38244.607083.55 ◽

2004 ◽

Vol 329 (7478) ◽

pp. 1321 ◽

Cited By ~ 76

Author(s):

Eran Kozer ◽

Winnie Seto ◽

Zulfikaral Verjee ◽

Chris Parshuram ◽

Sohail Khattak ◽

...

Keyword(s):

Emergency Department ◽

Observational Study ◽

Medication Errors ◽

Prospective Observational Study ◽

Paediatric Emergency Department ◽

Paediatric Emergency

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Drug-related problems among patients with infectious disease admitted to medical wards of Wollega University Referral Hospital: Prospective observational study

SAGE Open Medicine ◽

10.1177/2050312121989625 ◽

2021 ◽

Vol 9 ◽

pp. 205031212198962

Author(s):

Firomsa Bekele ◽

Ginenus Fekadu ◽

Kumera Bekele ◽

Dinka Dugassa ◽

Jiregna Sori

Keyword(s):

Infectious Disease ◽

Drug Therapy ◽

Observational Study ◽

Prospective Observational Study ◽

Referral Hospital ◽

Clinical Pharmacy Service ◽

Drug Related Problems ◽

Disease Etiology ◽

Co Morbidity ◽

Medical Wards

Introduction: Drug-related problems can affect the treatment outcomes of hospitalized patients and outpatients that lead to morbidity and mortality. Despite this, there were scanty of studies among patients with infectious diseases in Ethiopia. As the result, this study was tried to assess the magnitude and determinants of drug therapy problems among infectious disease patients admitted to the medical wards of Wollega University Referral Hospital. Methods: A prospective observational study was conducted from May to August 2019. The prevalence and types of drug- related therapy problems were studied using the Pharmaceutical Care Network Europe Foundation classification system, and adverse drug reaction was assessed by using the Naranjo algorithm. Multivariable logistic regression analysis was used to determine the predictors of drug-related problems, and a significant association was declared if p-value < 0.05. Result: Of the 172 study participants, 106 (61.6%) were males, and the patient’s mean age was 39.1 ± 14.31 years. Over the study period, 123 (71.51%) patients had drug-related problems. Need for additional drug therapy was the widely occurred drug-related problem that accounts for 107 (22.77%), and the most common drug-associated with the drug therapy problem was ceftriaxone (77 (44.77%)). This inappropriate use of ceftriaxone might be due to the preference of physicians to prescribe this broad spectrum antibiotic in which it was prescribed for the majority of the infectious disease etiology. Polypharmacy (adjusted odds ratio (AOR) = 2.505, 95% confidence interval (CI): 1.863–11.131), length of hospital stay ⩾ 7 days (AOR = 4.396, 95% CI: 1.964–7.310), and presence of co-morbidity (AOR = 2.107, 95% CI: 1.185–4.158, p = 0.016) were determinants of drug-related problems. Conclusion: The magnitude of drug-related problems was found to be high. Hence, the clinical pharmacy service should be established to tackle inappropriate indications, ineffective drug therapy, and adverse drug events in the study area.

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