scholarly journals A prospective study of the association between sickle cell disease and hepatobiliary effects in Bahrain

2017 ◽  
Vol Volume 10 ◽  
pp. 221-226
Author(s):  
Maheeba A Abdulla ◽  
Fajer Juma Almoosa ◽  
Rana Juma Al Moosa ◽  
Jehad Al Qamish
Keyword(s):  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
A Prospective Study

scholarly journals Neuropathic Pain in Children with Sickle Cell Disease: The Hidden Side of the Vaso-Occlusive Crisis

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 84
Author(s):  
Jeanne Sigalla ◽  
Nathalie Duparc Alegria ◽  
Enora Le Roux ◽  
Artemis Toumazi ◽  
Anne-Françoise Thiollier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neuropathic Pain ◽  
Sickle Cell Disease ◽  
Sex Ratio ◽  
Prospective Study ◽  
Sickle Cell ◽  
Clinical Presentation ◽  
Early Stage ◽  
Cell Disease ◽  
A Prospective Study

The majority of hospitalizations of patients with sickle cell disease (SCD) are related to painful vaso-occlusive crises (VOCs). Although the pain of VOC is classically nociceptive, neuropathic pain (NP) has also been demonstrated in SCD patients. The aim of our study is to specify the prevalence of NP during VOCs in SCD children using a dedicated scale and to measure its characteristics. We performed a prospective study that included SCD children hospitalized for an acute VOC. The presence of NP was sought with the DN4 scale on the second and fourth days of hospitalization. A total of 54 SCD children were included in the study. Overall, 41% of the patients (n = 22) experienced neuropathic pain during the VOC, mostly at an early stage (Day 2). The median age, the sex ratio, the location of the pain, and the morphine consumption were similar for patients with and without NP. Our study shows that neuropathic pain is very common during VOCs in SCD children. The absence of identified risk factors should prompt us to be vigilant regardless of the patient’s age, sex, and clinical presentation.

scholarly journals Clinical and haematological risk factors for cerebral macrovasculopathy in a sickle cell disease newborn cohort: a prospective study

2016 ◽  
Vol 172 (6) ◽  
pp. 966-977 ◽  
Author(s):  
Julie Sommet ◽  
Corinne Alberti ◽  
Nathalie Couque ◽  
Suzanne Verlhac ◽  
Zinedine Haouari ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
A Prospective Study

scholarly journals VARIOUS SURGICAL PRESENTATIONS AND THEIR OUTCOME IN SICKLE CELL DISEASE: A PROSPECTIVE STUDY

2015 ◽  
Vol 4 (81) ◽  
pp. 14207-14212
Author(s):  
Manju Singh ◽  
Sandeep Chandrakar ◽  
Amit Agrawal ◽  
Gambhir Singh
Keyword(s):  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
A Prospective Study

scholarly journals A Prospective Study to Compare the Maternal and Fetal Outcomes among Sickle Cell Disease and Trait Women

2019 ◽  
Vol 11 (6) ◽  
pp. 340-344
Author(s):  
Santosh Kumar Dora ◽  
Atal B Dandapat ◽  
Benudhar Pande ◽  
Ganeshram Bhoi ◽  
Bhawana Tiwari
Keyword(s):  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
Fetal Outcomes ◽  
A Prospective Study

A Prospective Study of Soft-Tissue Ultrasonography in Sickle Cell Disease Patients with Suspected Osteomyelitis

2000 ◽  
Vol 55 (4) ◽  
pp. 307-310 ◽  
Author(s):  
RANJAN R. WILLIAM ◽  
SAMIR S. HUSSEIN ◽  
WILLIAM D. JEANS ◽  
YASSER A. WALI ◽  
ZAKIA A. LAMKI
Keyword(s):  
Soft Tissue ◽  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
A Prospective Study

A Prospective Study of the Role of Coping and Family Functioning in Health Outcomes for Adolescents With Sickle Cell Disease

2007 ◽  
Vol 29 (11) ◽  
pp. 752-760 ◽  
Author(s):  
Lamia P. Barakat ◽  
Chavis A. Patterson ◽  
Beverley Slome Weinberger ◽  
Katherine Simon ◽  
Elizabeth R. Gonzalez ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Family Functioning ◽  
Health Outcomes ◽  
Prospective Study ◽  
Sickle Cell ◽  
Cell Disease ◽  
A Prospective Study

Sensorineural hearing loss in sickle cell disease-A prospective study from Oman

2011 ◽  
Vol 121 (2) ◽  
pp. 392-396 ◽  
Author(s):  
Muhammed Hesham Al Okbi ◽  
Salam Alkindi ◽  
Rashid K. Al Abri ◽  
John Mathew ◽  
Afarida A. Nagwa ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sickle Cell Disease ◽  
Prospective Study ◽  
Sensorineural Hearing Loss ◽  
Sickle Cell ◽  
Sensorineural Hearing ◽  
Cell Disease ◽  
A Prospective Study

scholarly journals Risk-Score Based Strategy to Minimize Antibiotic Exposure in Children With Sickle Cell Disease and Fever

2021 ◽  
Author(s):  
Elena Maria Rincón-López ◽  
María Luisa Navarro Gómez ◽  
Teresa Hernández-Sampelayo Matos ◽  
David Aguilera-Alonso ◽  
Eva Dueñas Moreno ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Risk Score ◽  
Bacterial Infections ◽  
Hospital Admissions ◽  
Empirical Therapy ◽  
Antibiotic Exposure ◽  
Cell Disease ◽  
Optimal Score ◽  
A Prospective Study

Abstract Severe bacterial infections (SBI) have become less frequent in children with sickle cell disease (SCD) in the last decades. However, because of their potential risk of SBI, they usually receive empirical therapy with broad-spectrum antibiotics when they develop fever and are hospitalized in many cases. We performed a prospective study including 79 SCD patients with fever [median age 4.1 (1.7–7.5) years, 78.5% males; 17 of the episodes were diagnosed with SBI and 4 of them were confirmed] and developed a risk score for the prediction of SBI. The optimal score included CRP > 3 mg/dl, IL-6 > 125 pg/ml and hypoxemia, with an AUC of 0.91 (0.83–0.96) for the prediction of confirmed SBI and 0.86 (0.77–0.93) for possible SBI. We classified the patients in 3 groups: low, intermediate and high risk of SBI. Our risk-score based management proposal could help to safely minimize antibiotic treatments and hospital admissions in children with SCD at low risk of SBI.

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