scholarly journals Overview of respiratory syncytial virus disease in young children

2012 ◽  
pp. 45 ◽  
Author(s):  
J. Michael Hoopes ◽  
Kumar
Keyword(s):  
Respiratory Syncytial Virus ◽  
Young Children ◽  
Virus Disease ◽  
Respiratory Syncytial Virus Disease ◽  
Syncytial Virus

scholarly journals Comparison of Risk Factors for Human Metapneumovirus and Respiratory Syncytial Virus Disease Severity in Young Children

2012 ◽  
Vol 206 (2) ◽  
pp. 178-189 ◽  
Author(s):  
Jesse Papenburg ◽  
Marie-Ève Hamelin ◽  
Najwa Ouhoummane ◽  
Julie Carbonneau ◽  
Manale Ouakki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Respiratory Syncytial Virus ◽  
Young Children ◽  
Disease Severity ◽  
Virus Disease ◽  
Human Metapneumovirus ◽  
Respiratory Syncytial Virus Disease ◽  
Syncytial Virus

scholarly journals Burden of Respiratory Syncytial Virus Disease and Mortality Risk Factors in Argentina

2019 ◽  
Vol 38 (6) ◽  
pp. 589-594 ◽  
Author(s):  
Angela Gentile ◽  
María Florencia Lucion ◽  
María del Valle Juarez ◽  
María Soledad Areso ◽  
Julia Bakir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Respiratory Syncytial Virus ◽  
Mortality Risk ◽  
Virus Disease ◽  
Respiratory Syncytial Virus Disease ◽  
Syncytial Virus

scholarly journals Respiratory Syncytial Virus Disease Severity in Young Children

2020 ◽  
Author(s):  
Zaid Haddadin ◽  
Stockton Beveridge ◽  
Kailee Fernandez ◽  
Danielle A Rankin ◽  
Varvara Probst ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Young Children ◽  
Disease Severity ◽  
Severity Score ◽  
Respiratory Infections ◽  
Virus Disease ◽  
Younger Age ◽  
Inpatient Settings ◽  
Syncytial Virus

Abstract Background Respiratory syncytial virus (RSV) is the leading cause of acute respiratory infections (ARIs) in hospitalized children. Although prematurity and underlying medical conditions are known risk factors, most of these children are healthy, and factors including RSV load and subgroups may contribute to severity. Therefore, we aimed to evaluate the role of RSV in ARI severity and determine factors associated with increased RSV-ARI severity in young children. Methods Children aged <5 years with fever and/or ARI symptoms were recruited from the emergency department (ED) or inpatient settings at Vanderbilt Children’s Hospital. Nasal and/or throat swabs were tested using quantitative reverse-transcription polymerase chain reaction for common respiratory viruses, including RSV. A severity score was calculated for RSV-positive children. Results From November 2015 through July 2016, 898 participants were enrolled, and 681 (76%) had at least 1 virus detected, with 191 (28%) testing positive for RSV. RSV-positive children were more likely to be hospitalized, require intensive care unit admission, and receive oxygen compared with children positive for other viruses. Higher viral load, White race, younger age, and higher severity score were independently associated with hospitalization in RSV-positive children. No differences in disease severity were noted between RSV A and RSV B. Conclusions RSV was associated with increased ARI severity in young children enrolled from the ED and inpatient settings, but no differences in disease severity were noted between RSV A and RSV B. These findings emphasize the need for antiviral therapy and/or preventive measures such as vaccines against RSV in young children.

Sign in / Sign up

Export Citation Format

Share Document