scholarly journals A cohort of French pediatric patients with primary immunodeficiencies: are patient preferences regarding replacement immunotherapy fulfilled in real-life conditions?

2017 ◽  
Vol Volume 11 ◽  
pp. 1171-1180 ◽  
Author(s):  
Marlène Pasquet ◽  
Isabelle Pellier ◽  
Nathalie Aladjidi ◽  
Anne Auvrignon ◽  
Patrick Cherin ◽  
...  
Keyword(s):  
Patient Preferences ◽  
Pediatric Patients ◽  
Real Life ◽  
Primary Immunodeficiencies ◽  
Life Conditions

Quality of life in HCV patients treated with OBV/PTV/r ± DSV ± RBV under real-life conditions – Data from the German observational study LIFE-C

2018 ◽  
Vol 56 (01) ◽  
pp. E2-E89
Author(s):  
P Buggisch ◽  
R Link ◽  
U Naumann ◽  
G Teuber ◽  
R Heyne ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Real Life ◽  
Life Conditions

scholarly journals An expandable approach for design and personalization of digital, just-in-time adaptive interventions

2018 ◽  
Vol 26 (3) ◽  
pp. 198-210 ◽  
Author(s):  
Suat Gonul ◽  
Tuncay Namli ◽  
Sasja Huisman ◽  
Gokce Banu Laleci Erturkmen ◽  
Ismail Hakki Toroslu ◽  
...  
Keyword(s):  
Real Life ◽  
Personal Data ◽  
Just In Time ◽  
Intervention Design ◽  
Intervention Delivery ◽  
Life Conditions ◽  
Triggering Conditions ◽  
Delivery Strategies ◽  
Design Mechanism ◽  
Personalized Intervention

AbstractObjectiveWe aim to deliver a framework with 2 main objectives: 1) facilitating the design of theory-driven, adaptive, digital interventions addressing chronic illnesses or health problems and 2) producing personalized intervention delivery strategies to support self-management by optimizing various intervention components tailored to people’s individual needs, momentary contexts, and psychosocial variables.Materials and MethodsWe propose a template-based digital intervention design mechanism enabling the configuration of evidence-based, just-in-time, adaptive intervention components. The design mechanism incorporates a rule definition language enabling experts to specify triggering conditions for interventions based on momentary and historical contextual/personal data. The framework continuously monitors and processes personal data space and evaluates intervention-triggering conditions. We benefit from reinforcement learning methods to develop personalized intervention delivery strategies with respect to timing, frequency, and type (content) of interventions. To validate the personalization algorithm, we lay out a simulation testbed with 2 personas, differing in their various simulated real-life conditions.ResultsWe evaluate the design mechanism by presenting example intervention definitions based on behavior change taxonomies and clinical guidelines. Furthermore, we provide intervention definitions for a real-world care program targeting diabetes patients. Finally, we validate the personalized delivery mechanism through a set of hypotheses, asserting certain ways of adaptation in the delivery strategy, according to the differences in simulation related to personal preferences, traits, and lifestyle patterns.ConclusionWhile the design mechanism is sufficiently expandable to meet the theoretical and clinical intervention design requirements, the personalization algorithm is capable of adapting intervention delivery strategies for simulated real-life conditions.

Open-Label Study of the Stability of Sublingual Nitroglycerin Tablets in Simulated Real-Life Conditions

2018 ◽  
Vol 122 (12) ◽  
pp. 2151-2156 ◽  
Author(s):  
James J. Nawarskas ◽  
Jason Koury ◽  
David A. Lauber ◽  
Linda A. Felton
Keyword(s):  
Real Life ◽  
Sublingual Nitroglycerin ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Life Conditions ◽  
The Stability

scholarly journals Method of verifying the emission level of the exhaust components of a special vehicle in relation to EURO III standard in road conditions

2021 ◽  
Author(s):  
Jędrzej Matla ◽  
Kaźmierczak Andrzej
Keyword(s):  
Test Object ◽  
Real Life ◽  
Exhaust Emission ◽  
Exhaust Gas ◽  
Emission Standard ◽  
Life Conditions ◽  
Measurement Results ◽  
Special Vehicle ◽  
Testing Mode ◽  
Mode A

The following article presents the method of verification of EURO III standard in real life conditions for special vehicles. The test object qualified as a special vehicle of N3G category was tested in road conditions along a defined route, and then the obtained measurement results were compared to the exhaust emission standard (EURO III) applicable for this vehicle in transient testing mode. A method of comparing the emission factors in road conditions with the indicators obtained on the engine dynamometer was proposed. An AVL mobile exhaust gas analyzers (PEMS) dedicated for the Real Driving Emissions (RDE) road tests were used in the research.

scholarly journals The formation of chemical literacy through environmental competencies in the application of case technology

2020 ◽  
Vol 132 (3) ◽  
pp. 150-155
Author(s):  
Sh.Sh. Khamzina ◽  
◽  
M.Т. Khassenova ◽  
Zh.S. Kassenova ◽  
◽  
...  
Keyword(s):  
Natural Science ◽  
Real Life ◽  
Pedagogical Issues ◽  
Case Method ◽  
Education Development ◽  
Modern Education ◽  
Life Conditions ◽  
Educational Task

The use of case technology in the formation of natural science, in particular chemical literacy, in chemistry lessons through the environmental competencies of students, is one of the effective tools. One of the requirements of modern education - the formation of competencies and the case method - is an effective way to implement this educational task. This method is based on the problem and its solution, allowing, thus, implementing several pedagogical issues: «training», «education», «development». At the same time, each student is given the opportunity to increase their cognitive interest, realize their potential and learn how to apply the acquired knowledge in real life conditions.

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