GC/MS spectroscopic approach, antimicrobial activity and cytotoxicity of some marine macroalgae from Qusier and Marsa Alam Seashore (Red Sea), Egypt

Objective: Microorganisms have developed resistance to existing available antibiotics, thereby thriving to anemerging need for new generation of antibiotics. Since seaweeds provide a rich source of bioactive molecules,the present study aimed to investigate its anti-microbial potential against clinically important microorganism.Methods: Redseaweed namelyGracilaria opuntia collected from different coastal regions of Gulf of Mannar and Rameswaram, India was used. For microbiological testing of the seaweed extracts, agar disc diffusion methodwas used.Results: The zone of inhibition was measured for all the different crude algal extracts against strains ofmicroorganisms such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia and Pseudomonasputidathat cause diseases in diabetic patients. Crude extracts prepared from aqueous, ethanol and methanol extraction procedures revealed that aqueous extraction procedure have a wide range of antimicrobial activity against all thetest pathogens.Conclusion: The overall antibacterial activity assessed from the above results indicates the presence of activeconstituents in the extractions of seaweeds which can be explored for the production of significant moleculeswhich could be used in pharmaceutical industry.

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Antimicrobial activity of a Red Sea soft coral, Parerythropodium fulvum fulvum:reproductive and developmental considerations

Marine Ecology Progress Series ◽

10.3354/meps169087 ◽

1998 ◽

Vol 169 ◽

pp. 87-95 ◽

Cited By ~ 40

Author(s):

D Kelman ◽

A Kushmaro ◽

Y Loya ◽

Y Kashman ◽

Y Benayahu

Keyword(s):

Antimicrobial Activity ◽

Red Sea ◽

Soft Coral

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Antimicrobial activity of the reef sponge Amphimedon viridis from the Red Sea: evidence for selective toxicity

Aquatic Microbial Ecology ◽

10.3354/ame024009 ◽

2001 ◽

Vol 24 ◽

pp. 9-16 ◽

Cited By ~ 78

Author(s):

D Kelman ◽

Y Kashman ◽

E Rosenberg ◽

M Ilan ◽

I Ifrach ◽

...

Keyword(s):

Antimicrobial Activity ◽

Red Sea ◽

Selective Toxicity

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Antimicrofouling activities of marine macroalga Dictyota dichotoma from the Red Sea

Journal of Agricultural and Marine Sciences [JAMS] ◽

10.24200/jams.vol23iss1pp58-67 ◽

2019 ◽

Vol 23 (1) ◽

pp. 58

Author(s):

Alaa Aref Gadhi ◽

Mohsen M. El-Sherbiny ◽

Abdul Mohsin Al-Sofynai ◽

Mohammad Abdulaziz Ba-Akdah ◽

Sathianeson Satheesh

Keyword(s):

Red Sea ◽

Bacterial Strain ◽

Extraction Methods ◽

Marine Macroalgae ◽

Dictyota Dichotoma ◽

Growth Inhibitory ◽

Microtitre Plate Assay ◽

Defence Strategies ◽

Marine Macroalga ◽

Total Extraction

Introduction. Marine organisms produce a variety of secondary metabolites mainly for achieving the defence against the competitors and predators. These compounds could be used as natural product antifoulants for the management of biofouling growth on marine structures. Objectives. To understand the antifouling defence strategies of marine macroalgae collected from the Red Sea. Methodology. The macroalga Dictyota dichotoma was collected from the Obhur Creek of Red Sea, Saudi Arabia and extracted using methanol. Surface and total extraction methods were performed and tested against a bacterial strain isolated from the microfouling assemblage. Results. The extracts obtained from the macroalgal samples have strong antibacterial and antibiofilm activities against the bacterial strain isolated from the marine microfouling assemblage. The total extracts showed strong bacterial growth inhibitory activities in culture plate method. In microtitre plate assay, surface extract showed strong biofilm inhibitory activity. GC-MS analysis indicated considerable variations in the metabolic profile of the surface and total extracts. Conclusion. This study revealed the importance of surface-associated compounds in antifouling defence mechanism of the marine macroalgae.

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