Predicting the Future: Phage Therapy

2022 ◽  
Vol 53 (1) ◽  
pp. 121-127
Author(s):  
farajolah maleki ◽  
sayad bastaminejad ◽  
saeed hemati
Keyword(s):  
Phage Therapy ◽  
The Future

Phage cocktails and the future of phage therapy

2013 ◽  
Vol 8 (6) ◽  
pp. 769-783 ◽  
Author(s):  
Benjamin K Chan ◽  
Stephen T Abedon ◽  
Catherine Loc-Carrillo
Keyword(s):  
Phage Therapy ◽  
The Future

The Promise of viral phage therapy in hernia mesh infection, is this the biological ‘silver bullet’ of the future?

2020 ◽  
Vol 90 (11) ◽  
pp. 2161-2164
Author(s):  
Peter Speck ◽  
Morgyn Warner ◽  
Jason Clark ◽  
Anita Jacombs ◽  
Alex Karatassas ◽  
...  
Keyword(s):  
Phage Therapy ◽  
Mesh Infection ◽  
Hernia Mesh ◽  
The Future ◽  
Silver Bullet

scholarly journals Phage Therapy: Consider the Past, Embrace the Future

2020 ◽  
Vol 10 (21) ◽  
pp. 7654
Author(s):  
Junwei Wei ◽  
Nan Peng ◽  
Yunxiang Liang ◽  
Keke Li ◽  
Yingjun Li
Keyword(s):  
Phage Therapy ◽  
Alternative Therapies ◽  
Resistant Bacteria ◽  
Application Process ◽  
Antibiotic Resistant ◽  
The Past ◽  
The Future ◽  
New Antibiotics ◽  
Potential Risks ◽  
Delivery Technology

Antibiotic-resistant bacteria infections pose a threat to public health. Considering the difficulty in developing new antibiotics, it is an urgent need to develop alternative therapies against bacterial pathogens. Bacteriophages (phages) are evaluated as potential substitutes or adjuncts of antibiotics because they are abundant in nature and could specifically lyse bacteria. In this review, we briefly introduce phage therapy and its advantages compared with traditional antibiotic therapy. We also summarize new emerging phage technologies, such as CRISPR-Cas, synthetic phages, etc., and discuss some possible obstacles and potential risks in the application process. We believe that, with the advancement in synthetic biology and delivery technology, phage therapy has broad prospects in the future.

Phage Therapy: A Potential Solution for Antibiotic Resistance

2021 ◽  
Author(s):  
Chirag Choudhary ◽  
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Infections ◽  
Phage Therapy ◽  
Biological Agents ◽  
Resistant Bacteria ◽  
Potential Solution ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant ◽  
The Future

The idea of using a virus to kill bacteria may seem counterintuitive, but it may be the future of treating bacterial infections. Before the COVID-19 pandemic, one of the most frightening biological agents were so-called “superbugs” – antibiotic resistant bacteria – which could not be treated with conventional therapeutics. When antibiotics were first developed, they were hailed as a panacea. A panacea they were not.

scholarly journals Bacterial infections in COVID-19 patients and their possible treatments. A review

2021 ◽  
Vol 27 (1) ◽  
pp. 6-14
Author(s):  
A'liyatur Rosyidah ◽  
Mohamad Padri ◽  
Paulus Damar Bayu Murti
Keyword(s):  
Antimicrobial Resistance ◽  
Severe Acute Respiratory Syndrome ◽  
Antimicrobial Peptides ◽  
Bacterial Infections ◽  
Phage Therapy ◽  
Treatment Decisions ◽  
Prevention And Treatment ◽  
The Future ◽  
In The Beginning

The COVID-19 pandemic, which started in the beginning of 2020 was triggered by a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, severely affected various sectors, especially health. The effect of COVID-19 on patients is exacerbated by bacterial co-infections and secondary bacterial infections. There are few studies on how bacterial co-infections and secondary bacterial infections worsen COVID-19 patients, including in Indonesia. Therefore, it is necessary to update and summarize the understanding of bacterial infections characteristics to help optimize the diagnosis, prevention, and treatment decisions. Antibiotics have been used in COVID-19 patients to treat bacterial infections to date, which could contribute to antimicrobial resistance in the future. The review s objective is to summarize bacterial infections in COVID-19 patients and several possible treatments, including antibiotics, phage therapy, probiotics/prebiotics, and nanomedicine for antimicrobial peptides (AMPs) delivery

scholarly journals The future of phage clinical trials in Australia

2019 ◽  
Vol 40 (1) ◽  
pp. 16
Author(s):  
Keith Potent
Keyword(s):  
Clinical Trials ◽  
Clinical Research ◽  
Phage Therapy ◽  
Tax Incentives ◽  
Innovative Development ◽  
Recent Success ◽  
Mainstream Medicine ◽  
The Future ◽  
Research Organisations

Australia is well positioned to conduct clinical trials in phage-based technology. Despite challenges with translating phage therapy to mainstream medicine, our regulations are designed for safe and innovative development. Recent success indicates that Australia is ideal for conducting further phage clinical trials. There are also expert clinical research organisations and generous tax incentives.

scholarly journals The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections

2020 ◽  
Vol 13 (1) ◽  
pp. 82-88
Author(s):  
Jonathan Anomaly
Keyword(s):  
Molecular Biology ◽  
Alternative Treatment ◽  
Bacterial Infections ◽  
Phage Therapy ◽  
Ethical Challenges ◽  
Moral Imperative ◽  
The World ◽  
The Future ◽  
Regulatory Challenges

Abstract For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments.

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