scholarly journals Phenotypes of B-Lymphocytes as a Predictor of Steroid Response in Idiopathic Nephrotic Syndrome.

GEGET ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. 28-35
Author(s):  
Faika Arab ◽  
Doaa Youssef ◽  
Fatma Ibrahim ◽  
Lobna El-korashi ◽  
Hoda Fathey
Keyword(s):  
Nephrotic Syndrome ◽  
B Lymphocytes ◽  
Idiopathic Nephrotic Syndrome ◽  
Steroid Response

scholarly journals Changes in Steroid Response pattern in Childhood Idiopathic Nephrotic Syndrome in Sohag

2017 ◽  
Vol 21 (1) ◽  
pp. 145-151
Author(s):  
Ghada abdelreheam ◽  
Ali Ahmed ◽  
Safaa Ali ◽  
Naglaa Ahmed
Keyword(s):  
Nephrotic Syndrome ◽  
Response Pattern ◽  
Idiopathic Nephrotic Syndrome ◽  
Steroid Response

Clinicopathologic characteristics and steroid response of IgM nephropathy in children presenting with idiopathic nephrotic syndrome

Apmis ◽  
2011 ◽  
Vol 119 (3) ◽  
pp. 180-186 ◽  
Author(s):  
MUHAMMED MUBARAK ◽  
JAVED I. KAZI ◽  
SHAHEERA SHAKEEL ◽  
ALI LANEWALA ◽  
SEEMA HASHMI ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Idiopathic Nephrotic Syndrome ◽  
Clinicopathologic Characteristics ◽  
Igm Nephropathy ◽  
Steroid Response

scholarly journals Impact of Urinary Tract Infection on Steroid Response in Idiopathic Nephrotic Syndrome in Children

2014 ◽  
Vol 13 (2) ◽  
pp. 1-3
Author(s):  
Tanuka Barua ◽  
Razia Sultana ◽  
Pradip Kumar Datta ◽  
Jhulan Das Sharma ◽  
Md Rezaul Karim ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Nephrotic Syndrome ◽  
Urinary Tract ◽  
Tract Infection ◽  
Idiopathic Nephrotic Syndrome ◽  
Female Ratio ◽  
Steroid Response ◽  
Group A ◽  
Group B ◽  
The Impact

Context: UTI is one of the most common infection in nephrotic syndrome and may be a cause of delayed steroid response. Objective:To observe the impact of urinary tract infection on steroid response in idiopathic nephrotic syndrome children aged 2-6 years.Study design: Quasi experimental study Study period & place: Pediatric ward of Chittagong Medical College Hospital, Chittagong from 01.01.2009 to 31.12.2009. Participants: 52 Nephrotic syndrome children aged 2-6 years with typical clinical features Group A: Nephrotic syndrome with UTI, Group B: Nephrotic syndrome without UTI. Methods: Heat coagulation test, urine for R/M/E and C/S was done in every patient. Steroid was given according to standard regimen. Date of starting of steroid was recorded. Antibiotic was given in group A cases according to C/S report. Patients were followed for clinical and urinary remission. Group A and B were compared for remission time achieved by statistical method.Results: A male preponderance was noted about 57.7% against female about 42.3%. Generalized swelling of body & scanty micturation found in cent percent study group. Ascitis was found in 23.08%. Scrotal/labial swelling 7.69%.UTI developed in 30.8% of patients of NS. Male female ratio is 1:1. Infection delayed the remission of proteinuria. Mean remission time of NS without UTI patients was 7.39 days and with UTI patients was 9.31 days. In statistical analysis, mean remission time in group A =9.31+2.24 days(mean + SD), in group B=7.39+2.51 days(mean + SD), P value = <0.05, statistically significant.Conclusion: UTI in nephrotic syndrome causes delayed remission of proteinuria and may be asymptomatic.It should be screened in every nephrotic syndrome children routinely.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i2.21046

scholarly journals FP172EXPRESSION OF P-GLYCOPROTEIN ON IMMUNE CELLS AFFECTS STEROID RESPONSE IN CHILDHOOD IDIOPATHIC NEPHROTIC SYNDROME

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii124-iii124
Author(s):  
Narayan Prasad ◽  
Akhilesh Jaiswal ◽  
Vikas Agarwal ◽  
Brijesh Yadav
Keyword(s):  
Nephrotic Syndrome ◽  
Immune Cells ◽  
Idiopathic Nephrotic Syndrome ◽  
Steroid Response ◽  
P Glycoprotein

RNA expression as a prognostic tool in idiopathic nephrotic syndrome

2007 ◽  
Vol 148 (23) ◽  
pp. 1067-1075
Author(s):  
Krisztina Fischer ◽  
Orsolya Galamb ◽  
Béla Molnár ◽  
Zsolt Tulassay ◽  
András Szabó
Keyword(s):  
Nephrotic Syndrome ◽  
Northern Blot ◽  
Idiopathic Nephrotic Syndrome ◽  
Minimal Change ◽  
Ribonuclease Protection Assay ◽  
Rna Expression ◽  
Rt Pcr ◽  
Protection Assay ◽  
Ribonuclease Protection

A gyermekkori nephrosis 90%-a idiopathiás nephrosis szindróma. Az idetartozó három kórkép, a minimal change betegség, a mesangialis proliferatio és a focalis sclerosis hasonló klinikai képpel jelentkező, eltérő prognózisú és terápiás válaszú betegség. Dolgozatunk célja az idiopathiás nephrosis szindrómába tartozó kórképek kialakulásával, progressziójával összefüggő genetikai ismeretek, génexpressziós változások áttekintése és funkcionális csoportosítása. A génexpressziós változások meghatározásának eszközeként, dolgozatunk röviden összefoglalja a northern blot, a ribonuclease protection assay, az in situ RNS-hibridizáció, a kvantitatív RT-PCR és a microarray módszerek lényegét. Az eddig elvégzett vizsgálatok a DNS-szintézis és repair gének, növekedési faktorok, extracelluláris mátrix, extracelluláris ligandreceptorok, extracelluláris jelátvitel zavarai mellett kiemelik a metabolikus és transzporter gének, illetve az immunszabályozó gének molekuláris eltéréseit, amelyek összefüggésben vannak az idiopathiás nephrosis szindróma eddig megismert molekuláris hátterével. A chiptechnológia fejlődésével és elterjedésével ezek a markerek és a hagyományos vizsgálati módszerek párhuzamos alkalmazása rutindiagnosztikai szempontból is fontossá válhat.

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