scholarly journals GENETIC AND ECONOMIC ANALYSIS FOR THE RELATIONSHIP BETWEEN UDDER HEALTH AND MILK PRODUCTION TRAITS IN FRIESIAN COWS

2009 ◽  
Vol 34 (8) ◽  
pp. 8667-8685
Author(s):  
H El-Awady ◽  
E. Oudah
Keyword(s):  
Economic Analysis ◽  
Milk Production ◽  
Production Traits ◽  
Milk Production Traits ◽  
Udder Health ◽  
The Relationship ◽  
Friesian Cows

scholarly journals Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

2020 ◽  
Vol 52 (1) ◽  
Author(s):  
Thierry Tribout ◽  
Pascal Croiseau ◽  
Rachel Lefebvre ◽  
Anne Barbat ◽  
Mekki Boussaha ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Candidate Genes ◽  
Milk Production ◽  
Association Studies ◽  
Genome Wide Association Studies ◽  
Nucleotide Polymorphisms ◽  
Production Traits ◽  
Milk Production Traits ◽  
Udder Health ◽  
Gwas Approach

Abstract Background Over the last years, genome-wide association studies (GWAS) based on imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci (QTL) and highlight candidate genes for important traits. However, in general this approach does not allow to validate the effects of candidate mutations or determine if they are truly causative for the trait(s) in question. To address these questions, we applied a two-step, within-breed GWAS approach on 15 traits (5 linked with milk production, 2 with udder health, and 8 with udder morphology) in Montbéliarde (MON), Normande (NOR), and Holstein (HOL) cattle. We detected the most-promising candidate variants (CV) using imputed WGS of 2515 MON, 2203 NOR, and 6321 HOL bulls, and validated their effects in three younger populations of 23,926 MON, 9400 NOR, and 51,977 HOL cows. Results Bull sequence-based GWAS detected 84 QTL: 13, 10, and 30 for milk production traits; 3, 0, and 2 for somatic cell score (SCS); and 8, 2 and 16 for udder morphology traits, in MON, NOR, and HOL respectively. Five genomic regions with effects on milk production traits were shared among the three breeds whereas six (2 for production and 4 for udder morphology and health traits) had effects in two breeds. In 80 of these QTL, 855 CV were highlighted based on the significance of their effects and functional annotation. The subsequent GWAS on MON, NOR, and HOL cows validated 8, 9, and 23 QTL for production traits; 0, 0, and 1 for SCS; and 4, 1, and 8 for udder morphology traits, respectively. In 47 of the 54 confirmed QTL, the CV identified in bulls had more significant effects than single nucleotide polymorphisms (SNPs) from the standard 50K chip. The best CV for each validated QTL was located in a gene that was functionally related to production (36 QTL) or udder (9 QTL) traits. Conclusions Using this two-step GWAS approach, we identified and validated 54 QTL that included CV mostly located within functional candidate genes and explained up to 6.3% (udder traits) and 37% (production traits) of the genetic variance of economically important dairy traits. These CV are now included in the chip used to evaluate French dairy cattle and can be integrated into routine genomic evaluation.

scholarly journals L-selectin gene polymorphism and its association with clinical mastitis, somatic cell score, and milk production in Polish Holstein-Friesian cattle

2018 ◽  
Vol 63 (No. 7) ◽  
pp. 256-262 ◽  
Author(s):  
M. Dusza ◽  
J. Pokorska ◽  
J. Makulska ◽  
D. Kulaj ◽  
M. Cupial
Keyword(s):  
Somatic Cell ◽  
Milk Production ◽  
Milk Fat ◽  
Bacterial Infections ◽  
Clinical Mastitis ◽  
Somatic Cell Score ◽  
Production Traits ◽  
Milk Production Traits ◽  
Holstein Friesian ◽  
Friesian Cows

Bovine mastitis is a widespread disease of the mammary gland, highly contributing to the increase in veterinary costs in dairy industry. In the present study, the genetic polymorphism within bovine L-selectin gene was analysed and its impact on clinical mastitis occurrence, somatic cell score (SCS), and milk production traits in Polish Holstein-Friesian cows was examined. Polymorphism within L-selectin gene, molecule responsible for neutrophil attachment to endothelium, might have a potential role in immune response to bacterial infections and udder health. Two hundred and six Polish Holstein-Friesian cows were genotyped by polymerase chain reaction-restriction fragment length polymorphism method. Two single nucleotide polymorphisms mutations within the coding sequence of L-selectin gene were identified (c.165G>A and c.567C>T). The effect of c.165G>A and c.567C>T mutations on SCS was highly significant (P = 0.0019 and P = 0.0003, respectively). Strong associations (P ≤ 0.0001) were also observed between L-selectin polymorphism and milk production traits (milk yield, milk fat percentage, and milk protein percentage). However, the polymorphism in the analysed gene had no influence on the resistance or susceptibility of cows to clinical mastitis (only the tendency toward significance, P = 0.06 for c.567C>T mutation was found). Potential exploitation of the information on the identified associations in genetic selection needs to confirm the obtained results in further investigations.

scholarly journals Temperament of Holstein Friesian cows in milking parlour and its relation to milk production

2008 ◽  
Vol 56 (1) ◽  
pp. 201-208 ◽  
Author(s):  
Andrea Szentléleki ◽  
Jeremy Hervé ◽  
Ferenc Pajor ◽  
Daniel Falta ◽  
János Tőzsér
Keyword(s):  
Milk Production ◽  
Milk Yield ◽  
Correlation Coefficients ◽  
Production Traits ◽  
Milk Production Traits ◽  
Point Scale ◽  
Milk Traits ◽  
Milk Flow ◽  
Holstein Friesian ◽  
Friesian Cows

The aim of this study was to evaluate the change of temperament of Holstein cows scored before and during milking during the entire lactation and to calculate correlation between temperament measured in the two moments as well as milk production traits and temperament. Observations were carried out on 17 primiparous Holstein Friesian cows starting their lactation within 85 days. Measurements of temperament and milk production traits were taken once in each month of the lactation, during the morning milking, in a milking parlour. Temperament was assessed in a 5-point scale during udder preparation and milking procedure (1: very nervous, 5: very quiet). Data of milk yield and milk flow were collected individually on each test day morning. Results showed changes during the lactation in temperament of cows scored directly before milking (P < 0.01), however, temperament during milking did not alter with months (P > 0.10). By correlation coefficients, behaviour assessed in the two moments cannot be regarded as the same. In addition loose, significant relations were found only between milk traits and temperament before milking.

scholarly journals Evaluation of associations of the polymorphism in the placentaspecific promoter 1.1 of the <i>CYP19</i> gene in Black-and-White and Jersey cattle with milk production traits (short communication)

2006 ◽  
Vol 49 (4) ◽  
pp. 311-314 ◽  
Author(s):  
M. Jędrzejczak ◽  
I. Szatkowska ◽  
S. Zych ◽  
W. Grzesiak ◽  
E. Czerniawska-Piątkowska ◽  
...  
Keyword(s):  
Milk Production ◽  
Short Communication ◽  
Production Traits ◽  
Milk Production Traits ◽  
P450 Gene ◽  
Black And White ◽  
Jersey Cattle ◽  
Pcr Rflp ◽  
Pvuii Polymorphism ◽  
The Relationship

Abstract. The relationship between the SNP of the cytochrome P450 gene (CYP19-PvuII) and milk production traits of Black-and-White and Jersey cattle were analysed. A total of 437 cows were included in the study. A PCR-RFLP was used to genotype. The frequencies of genotypes and alleles for the Black-and-White cows were as follows: 0.8985 – AA, 0.0977 – AB, 0.0038 – BB, and 0.9474 – CYP19A, 0.0526 – CYP19B. In the Jersey, all cows were genotyped as CYP19AA (no polymorphism). There weren’t any associations between CYP19-PvuII polymorphism and milk production traits of the investigated cows.

scholarly journals <i>GHRH/Hae</i>III gene polymorphism and its associations with milk production traits in Polish Black-and-White cattle (short communication)

2006 ◽  
Vol 49 (5) ◽  
pp. 434-438 ◽  
Author(s):  
A. Dybus ◽  
W. Grzesiak
Keyword(s):  
Gene Polymorphism ◽  
Milk Production ◽  
Short Communication ◽  
Production Traits ◽  
Milk Production Traits ◽  
Black And White ◽  
Pcr Rflp ◽  
White Cattle ◽  
The Relationship

Abstract. The objective of this paper was to evaluate the relationship between the polymorphism of the GHRH and milk production traits of Polish Black-and-White. A total of 881 cows were included in the study. A PCR-RFLP method was used to genotyping. The frequencies of the genotypes and alleles were as follows: 0.0545 for AA, 0.3133 for AB and 0.6322 for BB, and 0.2111 for GHRHA and 0.7889 – GHRHB. There were no significant associations between GHRH/HaeIII polymorphism and milk production traits of the analysed cows.

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