scholarly journals Is Multicentricity Important in Thyroid Papillary Microcarcinomas?

2019 ◽  
Vol 24 (6) ◽  
pp. 315
Author(s):  
Fatih Ciftci
Keyword(s):  
Thyroid Papillary ◽  
Papillary Microcarcinomas

Lymph node metastasis in thyroid papillary microcarcinoma: a study of 170 patients

2014 ◽  
Vol 128 (10) ◽  
pp. 922-925 ◽  
Author(s):  
R Varshney ◽  
M N Pakdaman ◽  
N Sands ◽  
M P Hier ◽  
L Rochon ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Central Compartment ◽  
Extrathyroidal Extension ◽  
Papillary Microcarcinoma ◽  
Extrathyroidal Invasion ◽  
Thyroid Papillary ◽  
Node Metastases ◽  
Tumour Characteristics ◽  
Papillary Microcarcinomas

AbstractObjective:Papillary microcarcinoma of the thyroid has been described as either a normal variant or a serious malignancy. We describe our experience with papillary microcarcinoma and lymph node metastases.Method:A total of 685 consecutive total thyroidectomies with central compartment neck dissection were reviewed for papillary microcarcinoma. Association of central compartment lymph node metastases with age, gender, tumour multifocality, bilaterality and extrathyroidal extension was analysed.Results:Out of 170 papillary microcarcinoma cases, multifocality was found in 72 (42.4 per cent), bilaterality in 49 (28.8 per cent) and extrathyroidal extension in 16 (9.4 per cent). In all, 23 patients (13.5 per cent) had lymph node metastases. There was a significant association (p < 0.05) between extrathyroidal extension (but no other tumour characteristics) and lymph node metastases.Conclusion:In all, 13.5 per cent of papillary microcarcinomas in our series showed lymph node metastases. Lymph node metastases were associated with extrathyroidal invasion of the papillary microcarcinoma.

Can [18F]-Fluorodeoxyglucose Standardized Uptake Values of PET Imaging Predict Pathologic Extrathyroid Invasion of Thyroid Papillary Microcarcinomas?

2006 ◽  
Vol 116 (12) ◽  
pp. 2133-2137 ◽  
Author(s):  
Han-Sin Jeong ◽  
Manki Chung ◽  
Chung-Hwan Baek ◽  
Young-Hyeh Ko ◽  
Joon-Young Choi ◽  
...  
Keyword(s):  
Pet Imaging ◽  
18F Fluorodeoxyglucose ◽  
Standardized Uptake Values ◽  
Thyroid Papillary ◽  
Papillary Microcarcinomas

Revisiting Low-Risk Thyroid Papillary Microcarcinomas Resected Without Observation: Was Immediate Surgery Necessary?

2015 ◽  
Vol 40 (3) ◽  
pp. 523-528 ◽  
Author(s):  
Yasuhiro Ito ◽  
Akira Miyauchi ◽  
Hitomi Oda ◽  
Kaoru Kobayashi ◽  
Minoru Kihara ◽  
...  
Keyword(s):  
Low Risk ◽  
Thyroid Papillary ◽  
Immediate Surgery ◽  
Papillary Microcarcinomas

scholarly journals Metastatic thyroid papillary microcarcinomas

2014 ◽  
Author(s):  
Cigdem Tura Bahadir ◽  
Elif Kilic Kan ◽  
Feyzi Gokosmanoglu ◽  
Gulcin Cengiz Ecemis ◽  
Hulusi Atmaca
Keyword(s):  
Thyroid Papillary ◽  
Papillary Microcarcinomas

scholarly journals ‘Incidental’ and ‘non-incidental’ thyroid papillary microcarcinomas are two different entities

2016 ◽  
Vol 174 (6) ◽  
pp. 813-820 ◽  
Author(s):  
Maria Annateresa Provenzale ◽  
Emilio Fiore ◽  
Clara Ugolini ◽  
Liborio Torregrossa ◽  
Riccardo Morganti ◽  
...  
Keyword(s):  
Tumor Size ◽  
Nodular Goiter ◽  
Benign Disease ◽  
Cytological Diagnosis ◽  
Papillary Thyroid ◽  
Histological Features ◽  
Thyroid Papillary ◽  
Papillary Microcarcinomas ◽  
Serum Tsh ◽  
Tsh Levels

Objective Papillary thyroid microcarcinomas (microPTC) may be ’incidental’ (Inc-microPTC), occasionally found at histology after surgery for benign disease or ‘non-incidental’ (Non-Inc-microPTC), diagnosed on clinical grounds. It is unclear whether these different microPTC reflect the same disease. The aim of the study was to compare Inc-microPTC and Non-Inc-microPTC for clinical and histological features as well as for serum TSH, a known factor involved in PTC development. Design We evaluated histology and serum TSH levels of consecutive patients submitted to thyroidectomy for goiter with compressive symptoms or for cytological diagnosis suspicious/indicative of PTC. Methods In total, 665 consecutive patients (259 with a single thyroid nodule, SN and 406 with a multinodular gland, MN) were included in the study. According to histology, patients were classified as: benign nodular goiter (Benign, n=291); Inc-microPTC (n=92); Non-Inc-microPTC (n=67) and PTC≥1cm (macroPTC, n=215). Results Inc-microPTC were significantly more frequent in MN than in SN (66/406, 16.2% vs 26/259, 10.0%, P=0.02). Patients with Inc-microPTC compared with Non-Inc-microPTC were older (mean age±s.d. 53.3±13.2 years vs 44.9±14.8 years, P=0.0002), had a smaller tumor size (median 4mm vs 9mm, P<0.0001), a higher frequency of multifocality (70/92, 76.1% vs 35/67, 52.2% P=0.001) and lower levels of TSH (median 0.6mIU/L, IR: 0.4–1.0mIU/L vs value 1. mIU/L, IR: 0.6–1.4mIU/L vs P=0.0001). Conclusion Incidental and non-incidental papillary thyroid microcarcinomas appear to be two different entities.

Multicentricity in thyroid papillary microcarcinomas

2010 ◽  
Vol 26 (4) ◽  
pp. 199
Author(s):  
Varlik Erol ◽  
Ozer Makay ◽  
Yesim Ertan ◽  
Gokhan Icoz ◽  
Mahir Akyildiz ◽  
...  
Keyword(s):  
Thyroid Papillary ◽  
Papillary Microcarcinomas

scholarly journals Underexpression of p27/Kip in Thyroid Papillary Microcarcinomas With Gross Metastatic Disease

2002 ◽  
Vol 128 (3) ◽  
pp. 253 ◽  
Author(s):  
Mark L. C. Khoo ◽  
Jeremy L. Freeman ◽  
Ian J. Witterick ◽  
Jonathan C. Irish ◽  
Lorne E. Rotstein ◽  
...  
Keyword(s):  
Metastatic Disease ◽  
Thyroid Papillary ◽  
Papillary Microcarcinomas

Confronting the practice of surgery on differentiated thyroid cancer with current guidelines in Germany

2005 ◽  
Vol 44 (05) ◽  
pp. 185-191 ◽  
Author(s):  
H. Wieler ◽  
S. Birtel ◽  
E. Ostwald-Lenz ◽  
K. P. Kaiser ◽  
H. P. Becker ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Survival Rates ◽  
Perioperative Morbidity ◽  
Referral Hospitals ◽  
Principles Of Treatment ◽  
Current Guidelines ◽  
Papillary Microcarcinomas ◽  
Retrospective Multicenter Study

Summary:Aim: For the surgical therapy of differentiated thyroid cancer precise guidelines are applied by the German medical societies. In a retrospective multicenter study, we investigated the following issues: Are the current guidelines respected?. Is there a difference concerning the surgical radicalism and the outcome?. Does the perioperative morbidity increase with the higher radicalism of the procedure?. Patients, methods: Data gained from 102 patients from 17 regional referral hospitals who underwent surgery for thyroid cancer and a following radioiodine treatment (mean follow up: 42.7 [24-79] months) were analyzed. At least 71 criterias were analyzed in a SPSS file. Results: 46.1% of carcinomas were incidentally detected during goiter surgery. The thyroid cancer (papillary n = 78; follicular n = 24) occurred in 87% unilateral and in 13% bilateral. Papillary carcinomas <1 cm were detected in 25 cases; in five of these cases (20%) contralateral carcinomas <1 cm were found. There were significant differences concerning the surgical radicalism: a range from hemithyroidectomy to radical thyroidectomy with lateral neck dissection. Analysis of the histopathologic reports revealed that lymph node dissection was not performed according to guidelines in 55% of all patients. The perioperative morbidity was lower in departments with a high case load. The postoperative dysfunction of the recurrent laryngeal nerve (mean: 7.9% total / 4.9% nerves at risk) variated highly, depending on differences in radicalism and hospitals. Up to now these variations in surgical treatment have shown no differences in their outcome and survival rates, when followed by radioiodine therapy. Conclusion: Current surgical regimes did not follow the guidelines in more than 50% of all cases. This low acceptance has to be discussed. The actual discussion about principles of treatment regarding, the socalled papillary microcarcinomas (old term) has to be respected within the current guidelines.

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