scholarly journals Antibody to Hepatitis B Surface Antigen (Anti-HBs) Induced by a Recombinant Hepatitis B Vaccine Consisting of Subtype adr Antigen is Underestimated on the World Health Organization (WHO)-standardized Assay

2003 ◽  
Vol 42 (5) ◽  
pp. 446-447 ◽  
Author(s):  
Norio OGATA ◽  
Shutaro TAKASHIMA ◽  
Kikuko SHIMAKI ◽  
Isao KITAJIMA ◽  
Akiharu WATANABE
2021 ◽  
Vol 2 (4) ◽  
pp. 1-8
Author(s):  
Gabriela Mitea ◽  
Marius Daniel Radu ◽  
Ana Maria Ionescu ◽  
Nicoleta Blebea

In infectious diseases, viral hepatitis has an increased incidence, being an important cause of morbidity and mortality, being a "sentinel" indicator of the socio-economic and hygienic-cultural standard of a geographical area. The World Health Organization (WHO) admits the following types of hepatitis viruses: A, B, B + D, C, E, F and G. Among the viral entities recognized by the WHO, a special importance in terms of incidence, evolution over time with the risk of chronicity and the therapeutic options are presented by hepatitis B and C. There is currently an effective vaccine as well as treatment for hepatitis B. There is no vaccine for hepatitis C, but in recent years considerable progress has been made in treating this disease. Also, the introduction of drugs known as direct-acting antivirals makes it possible to cure over 90% of patients within 2-3 months. But in many countries, current drug policies, regulations and prices keep treatment out of the reach of most people with hepatitis. Eradication of viral hepatitis is possible if greater emphasis is placed on prevention, diagnosis and treatment. Vaccination is very important, as it is possible for types A and B of hepatitis. Early diagnosis is also extremely important, given that there are currently very effective drugs that can prevent the development of liver cancer. The WHO also noted that about two million people worldwide become ill each year due to the reuse of syringes and stressed the importance of checking blood donors to see if they are not carriers of hepatitis B or C viruses. Therefore, the purpose of this article is to highlight the pharmacological treatment and the main therapeutic and prevention schemes currently used for patients with these liver diseases. The paper was based on the most popular methods of identification of the latest international information about the treatment of hepatitis (by electronic search using Pubmed, SciFinder, Scirus, GoogleScholar and Web of Science). We also consulted the global literature cited in the hepatitis database of the World Health Organization (WHO) updated frequent from the current literature on this topic.


Vaccine ◽  
2016 ◽  
Vol 34 (21) ◽  
pp. 2403-2409 ◽  
Author(s):  
Robert D. Allison ◽  
Nadia Teleb ◽  
Salah Al Awaidy ◽  
Hossam Ashmony ◽  
James P. Alexander ◽  
...  

2021 ◽  
pp. 002200942110578
Author(s):  
Gaëtan Thomas

This article explores the role of the World Health Organization (WHO) within the tumultuous history of the hepatitis B vaccine in France, including a controversy that erupted in 1996 and lasted several years. When the first hepatitis B vaccine was commercialized in France in 1981, it inaugurated a new era in the industry characterized by high prices, an unprecedented number of patents and aggressive commercial competition. By inscribing the hepatitis B vaccine controversy into a broader, global history of the economization of immunization – in which the WHO played a central role – this article reframes the causes and implications of a controversy that both actors and scholars have approached through a primarily national lens. The challenge posed to the economic approach to immunization prepared the ground for subsequent critiques of vaccines as commodities. The article discusses a key transformation in the recent transatlantic history of public health by focusing on the perceived association of immunization with a contested economic order.


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