scholarly journals Pharmacotherapeutic management of chronic viral hepatitis

2021 ◽  
Vol 2 (4) ◽  
pp. 1-8
Author(s):  
Gabriela Mitea ◽  
Marius Daniel Radu ◽  
Ana Maria Ionescu ◽  
Nicoleta Blebea

In infectious diseases, viral hepatitis has an increased incidence, being an important cause of morbidity and mortality, being a "sentinel" indicator of the socio-economic and hygienic-cultural standard of a geographical area. The World Health Organization (WHO) admits the following types of hepatitis viruses: A, B, B + D, C, E, F and G. Among the viral entities recognized by the WHO, a special importance in terms of incidence, evolution over time with the risk of chronicity and the therapeutic options are presented by hepatitis B and C. There is currently an effective vaccine as well as treatment for hepatitis B. There is no vaccine for hepatitis C, but in recent years considerable progress has been made in treating this disease. Also, the introduction of drugs known as direct-acting antivirals makes it possible to cure over 90% of patients within 2-3 months. But in many countries, current drug policies, regulations and prices keep treatment out of the reach of most people with hepatitis. Eradication of viral hepatitis is possible if greater emphasis is placed on prevention, diagnosis and treatment. Vaccination is very important, as it is possible for types A and B of hepatitis. Early diagnosis is also extremely important, given that there are currently very effective drugs that can prevent the development of liver cancer. The WHO also noted that about two million people worldwide become ill each year due to the reuse of syringes and stressed the importance of checking blood donors to see if they are not carriers of hepatitis B or C viruses. Therefore, the purpose of this article is to highlight the pharmacological treatment and the main therapeutic and prevention schemes currently used for patients with these liver diseases. The paper was based on the most popular methods of identification of the latest international information about the treatment of hepatitis (by electronic search using Pubmed, SciFinder, Scirus, GoogleScholar and Web of Science). We also consulted the global literature cited in the hepatitis database of the World Health Organization (WHO) updated frequent from the current literature on this topic.

Vaccine ◽  
2016 ◽  
Vol 34 (21) ◽  
pp. 2403-2409 ◽  
Author(s):  
Robert D. Allison ◽  
Nadia Teleb ◽  
Salah Al Awaidy ◽  
Hossam Ashmony ◽  
James P. Alexander ◽  
...  

2021 ◽  
Vol 75 ◽  
pp. 58-63
Author(s):  
Martyna Biała ◽  
Edyta Lelonek ◽  
Brygida Knysz

In December 2019 the first cases of atypical pneumonia caused by a novel coronavirus SARS-CoV-2 were reported in Wuhan, China. This new infection was called coronavirus disease 2019 (COVID-19). SARS-CoV-2 is primarily transmitted human-to-human via direct contact and via the air-respiratory droplets and/or aerosols. The clinical manifestations of COVID-19 could range from asymptomatic or mild non-specific symptoms to severe pneumonia with multiple organ failure and death. The virus spread rapidly to almost all the countries in the world within a few months, and on the 11th of March 2020, the World Health Organization (WHO) announced the COVID-19 pandemic. Since then, a dynamic increase in the number of COVID-19 infections and deaths has been recorded worldwide. The COVID-19 pandemic is accelerating and causing annex tensive impact on the functioning of health care and is also leading to an economic crisis in the world. Today, it is difficult to ultimately assess the long-term effects of the pandemic, although it is known that they will be experienced for decades. Therefore, the most important goal is to stop the pandemic and develop an effective vaccine against SARS-CoV-2. Using the ClinicalTrials.gov and World Health Organization databases, we shed light on the current worldwide clinical and pre-clinical trials in search for a COVID-19 vaccine.


2017 ◽  
Vol 7 (1) ◽  
pp. 40-42

ABSTRACT The World Health Organization (WHO) has adopted targets unanimously at the World Health Assembly in July 2016, in Geneva, to significantly curtail hepatitis B and C viruses to near extinction by 2030. Preparations are now ongoing in all WHO member nations across the globe to reach this ambitious, but perhaps achievable target. In Bangladesh, hepatologists, nongovernmental organizations, civil society, and patients have joined hands with the government in this global fight against viral hepatitis. How to cite this article Mahtab MA. Elimination of Hepatitis Viruses: Bangladesh Scenario. Euroasian J Hepato-Gastroenterol 2017;7(1):40-42.


Author(s):  
Farzin Bagheri Sheykhangafshe

Introduction: Coronavirus 2019 (COVID-19), as the biggest threat to public health in 2020, has caused many problems to people around the world during the current year. The COVID-19, which first appeared in Wuhan, China, was designated as acute respiratory syndrome 2 by the International Commission on Classification of Diseases World Health Organization and on March 11, 2020, it was introduced as a pandemic worldwide. From the earliest days, scientists and physicians have been working to discover and develop an effective vaccine for the coronavirus 2019. Finally, after much effort, several vaccines were approved by the World Health Organization. Many factors can play a role in the safety of vaccines, in this regard, psychological characteristics of individuals is one of the most important factors that can affect the effectiveness of COVID-19 vaccine. Considering that the medical staff of each country is one of the first group to receive the COVID-19 vaccine, so it is necessary they will be examined and evaluated in terms of psychological characteristics in order to provide the necessary psychological interventions if necessary. Iran, on February 9, 2021, started the nationwide vaccination using the Sputnik-V vaccines. Given that mental health can also affect the efficacy of the COVID-19 vaccine, it is recommended that samples be examined domestically for various psychological characteristics such as levels of stress, fear, depression and anxiety should be evaluated to see the best results and effectiveness of the COVID-19 virus vaccine in Iran.


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