scholarly journals 2) Diabetes Mellitus Characterized by Impaired Insulin Secretion in Japanese

2016 ◽  
Vol 105 (3) ◽  
pp. 396-401
Author(s):  
Nobuya Inagaki
1986 ◽  
Vol 23 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Antonio Quatraro ◽  
Giuseppe Consoli ◽  
Aldo Stante ◽  
Arcangelo Minei ◽  
Antonio Ceriello ◽  
...  

2017 ◽  
Vol 3 (2) ◽  
pp. 55
Author(s):  
Widodo Widodo

Diabetes mellitus is a disease characterized by hyperglycemia, which is caused by impaired insulin secretion, impaired insulin action, or both. Chronic hyperglycemia will lead to dysfunction and damage to various organs, such as the eyes, kidneys, nerves, heart, and blood vessels. This paper discusses the monitoring of patients with diabetes mellitus according to the laboratory tests, to know when the results of therapy has reached the optimum point as well as the prevention of complications that can occur.  


Diabetes ◽  
1985 ◽  
Vol 34 (9) ◽  
pp. 861-869 ◽  
Author(s):  
W. K. Ward ◽  
C. L. Johnston ◽  
J. C. Beard ◽  
T. J. Benedetti ◽  
J. B. Halter ◽  
...  

1981 ◽  
Vol 6 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Dario Giugliano ◽  
Saverio Sgambato ◽  
Ludovico Coppola ◽  
Lucio Misso ◽  
Roberto Torella

2009 ◽  
Vol 10 (1) ◽  
pp. 23-27
Author(s):  
Takeshi Ito ◽  
Nobuya Fujita ◽  
Naoki Maeda ◽  
Masayoshi Komura ◽  
Hideto Tomioka ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Seishi Furukawa ◽  
Yoichi Kobayashi

Aim. To identify the involvement of leanness and impaired insulin secretion with Japanese gestational diabetes mellitus (GDM). Method. A cross-sectional study was conducted comprising 219 at-risk pregnant women who underwent a 75g glucose tolerance test at a single institute in Tokyo, Japan. We identified GDM and normal glucose tolerance (NGT). The cut-off value of the homeostasis model assessment insulin resistance (HOMA-IR) for detecting GDM was determined. The GDM group was divided into subgroups according to insulin resistance based on the cut-off value of HOMA-IR. We compared the prepregnancy body mass index (BMI) and homeostasis model assessment of β-cell function (HOMA-β) between the group comprising low insulin resistance (LIR) and the group comprising high insulin resistance (HIR). Results. Seventy GDM cases and 149 NGT cases were identified. By using receiver operating characteristic curve analysis, the HOMA-IR cut-off value was determined to be 1.41. Twenty-five GDM cases (36%) were classified as LIR and forty-five GDM cases (64%) were classified as HIR. The background including indications for having 75gOGTT and the gestational age having 75gOGTT did not differ between groups. The BMI of the LIR group was significantly lower than that of the HIR group (20.9±2.8 vs. 24.4 ± 5.5, p<0.01), and the HOMA-β of the LIR group was significantly lower than that of the HIR group (95.5±30.3 vs. 146.0±70.1, p<0.01). A positive linear correlation was found between BMI and HOMA-β in cases of GDM (r=0.27, p=0.02). Conclusion. Leanness with impaired insulin secretion is deeply involved in Japanese gestational diabetes mellitus.


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