scholarly journals Anemia : The advances in diagnosis and treatment. The fundamentals of red blood cells and anemia. The basics for the diagnosis and the selection of treatment for anemia.

1990 ◽  
Vol 79 (5) ◽  
pp. 575-580
Author(s):  
TATSUMI UCHIDA
2019 ◽  
Vol 1 (2) ◽  
pp. 17
Author(s):  
Muhammad Imran Qadir ◽  
Fatima Hameed

The total amount of 100 subjects were contributed in this review and all were the students who are studying in Bahauddin Zakariya University Multan, Pakistan. The bilirubin is metabolized in the gut which produced a colorless pigment known as urobilinogen. It is by-product of bilirubin which is used to break down the red blood cells in hemolysis. Salty food contains usually more minerals and vitamins while sweet food is enriched with carbohydrates, water and many other fats soluble substances. Every person has a unique taste according to their taste buds. A questionnaire based was made to relate the urobilinogen with the food (salty or sweet). Urinalysis is a method which is used to measure the urobilinogen in urine. It was concluded that there is a scientific relation between the presence of urobilinogen in urine with eating of salty or sugary food. Table no. 1 represents that urobilinogen play important role in the choice of eating either salty food more or sweet.


1963 ◽  
Vol 39 (6) ◽  
pp. 562-566 ◽  
Author(s):  
W. Newlon Tauxe ◽  
James L. Becton ◽  
Mitsue Y. Yamaguchi

2019 ◽  
Vol 64 (4) ◽  
pp. 221-224
Author(s):  
A. V. Yovdiy ◽  
E. V. Butina ◽  
E. A. Poponina ◽  
G. A. Zaitseva ◽  
N. V. Minaeva

The correct determination of the blood types of the recipient and the donor is very importante for the choice of blood components for transfusion. As a result of the study, it was established that 18.0% of patients, admitted to the hematology clinic, have difficulties in interpreting of the results of immunohematological tests. Most often, a double population of red blood cells was detected when determining antigens of the Rhesus system (10.9%), auto- (3.9%) and alloantibodies (2.8%). The proposed algorithm for the selection of donor red blood cells in difficult diagnostic cases helps to prevent the development of post-transfusion complications.


2019 ◽  
Vol 71 (1) ◽  
pp. 93-101
Author(s):  
M.N.A. Marchi ◽  
P.E. Luz ◽  
R.R. Martins ◽  
S.M. Simonelli ◽  
U.P. Pereira ◽  
...  

ABSTRACT The objective of this study was to perform a quality control assessment of red blood cells after standardization of the blood production stages. For this purpose, separation of the blood components to obtain red blood cells, the storage of the blood packets and an evaluation of blood quality were performed. The mean (± SD) volume, globular volume, hemoglobin and hemolysis percentage of the red blood cell concentrate were 299.77±30.08mL, 60.87±2.60%, 20.57±0.93g/DL and 0.09±0.07%, respectively. The means (± SD) of the volume, globular volume, total hemoglobin percentage of hemolysis and hemoglobin per unit of packed red blood cells after the storage period (8.83±6.73 days) were 57.55±3.01%, 20.30±0.89 0, 20±0.12%, and 60.90±7.65. The red blood cell packets were within the parameters of quality control established by Health Ministry legislation in humans and allow us to conclude that the standardization of blood production stages involves the selection of donors until the end of storage and is necessary to produce quality red blood cells. Quality control aims to find possible flaws in the procedures to be repaired, increasing transfusion safety.


1999 ◽  
Vol 14 (Suppl_3) ◽  
pp. 236-237
Author(s):  
A.P. Goud ◽  
M. De Smedt ◽  
H. Laverge ◽  
P.T. Goud ◽  
J. Plum ◽  
...  

2019 ◽  
Vol 64 (4) ◽  
pp. 504-515
Author(s):  
L. L. Golovkina ◽  
R. S. Kalandarov ◽  
A. G. Stremoukhova ◽  
O. S. Kalmykova ◽  
T. D. Pushkina ◽  
...  

Introduction. The identification of weak variants of the A antigen, as well as their differentiation, is necessary for the proper selection of erythrocyte-containing media for blood transfusions. To this end, selective anti-A1 reagents that react only with the A1 antigen are used in combination with anti-A reagents reacting equally with the A1 and A2 antigens. Given that the expression of the A antigen varies within the subgroups and there is no established standard for reagents and procedures, the interpretation of the obtained results presents difficulties.Aim. To develop a strategy for identifying the variants of the A antigen using available reagents in an agglutination reaction.Methods. We compared the effectiveness of four anti-A1 and two anti-H reagents using 23 blood samples (groups A2 and A2B) and control samples (groups A1 and A1 B). Two types of anti-A1 reagents were employed: Dolychos biflorus lectin and monoclonal antibodies. All of the reagents were designed for direct agglutination reactions. Belonging of the erythrocytes to the A2 subgroup was confirmed using genetic analysis.Results. It is shown that anti-A1 reagents did not interact with A2B red blood cells and often reacted with A2 red blood cells. The strength of the reaction with A2 red blood cells varied greatly and was weaker than with A1 red blood cells; however, it hindered the subgroup identification. Simultaneous tests conducted using an anti-H reagent allowed the authors to draw an unambiguous conclusion about blood belonging to a subgroup: a strong reaction indicated the A2 subgroup, whereas a negative or weak reaction indicated the A1 subgroup. A discrepancy was noted between the results obtained for two donors using serological and molecular methods: the A3 subgroup was identified serologically, whereas genotyping revealed the AB0*A1 allele. In both cases, direct sequencing showed a combination of mutant alleles giving the A3 phenotype. When using commercial kits to perform genotyping analysis through a polymerase chain reaction, it should be taken into consideration that primers are matched to the most common variants and cannot detect all mutations of the AB0 gene.Conclusion. Reliable identification of the A2 subgroup through serological methods is possible when using lectin or monoclonal anti-A1 antibodies in combination with a monoclonal anti-H reagent.Conflict of interest: the authors declare no conflict of interest.Financial disclosure: the study had no sponsorship.


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