Phosphorylation of a Heme-Regulated Eukaryotic Initiation Factor 2αkinase Enhances the Interaction with Heat-Shock Protein 90 and Substantially Upregulates kinase Activity

Protein and Peptide Letters ◽

10.2174/092986611797642733 ◽

2011 ◽

Vol 18 (12) ◽

pp. 1251-1257 ◽

Author(s):

Kentaro Mukai ◽

Toru Shimizu ◽

Jotaro Igarashi

Keyword(s):

Heat Shock Protein ◽

Kinase Activity ◽

Heat Shock Protein 90 ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)31477-7 ◽

1993 ◽

Vol 268 (17) ◽

pp. 12946-12951 ◽

Author(s):

P. Murtha-Riel ◽

M.V. Davies ◽

B.J. Scherer ◽

S.Y. Choi ◽

J.W. Hershey ◽

...

Keyword(s):

Protein Synthesis ◽

Initiation Factor ◽

Alpha Subunit ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Inhibition Of Protein Synthesis ◽

Initiation Factor 2

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RAT FIBROBLASTS TRANSFECTED WITH THE HUMAN HSP70 GENE EXHIBIT ALTERED PHOSPHORYLATION OF EUKARYOTIC INITIATION FACTOR 2 FOLLOWING HEAT SHOCK

Radiation Research: A Twentieth-century Perspective ◽

10.1016/b978-0-12-168561-4.50374-7 ◽

1991 ◽

pp. 477

Author(s):

G.C. Chang ◽

R.Y. Liu ◽

G.C. Li

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Rat Fibroblasts ◽

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Mutation at the acidic residue-rich domain of eukaryotic initiation factor 2 (eIF2α)-associated glycoprotein p67 increases the protection of eIF2α phosphorylation during heat shock

Archives of Biochemistry and Biophysics ◽

10.1016/s0003-9861(03)00092-4 ◽

2003 ◽

Vol 413 (1) ◽

pp. 116-122 ◽

Author(s):

Bansidhar Datta ◽

Rekha Datta

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Rich Domain ◽

Eif2α Phosphorylation ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Isolation of eukaryotic initiation factor 2 from yeast Saccharomyces cerevisiae.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)69920-5 ◽

1981 ◽

Vol 256 (3) ◽

pp. 1063-1066

Author(s):

R.A. Baan ◽

P.B. Keller ◽

A.E. Dahlberg

Keyword(s):

Saccharomyces Cerevisiae ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Yeast Saccharomyces Cerevisiae ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Evidence that the primary effect of phosphorylation of eukaryotic initiation factor 2(alpha) in rabbit reticulocyte lysate is inhibition of the release of eukaryotic initiation factor-2.GDP from 60 S ribosomal subunits.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)39391-2 ◽

1985 ◽

Vol 260 (16) ◽

pp. 9491-9500 ◽

Author(s):

M Gross ◽

R Redman ◽

D A Kaplansky

Keyword(s):

Initiation Factor ◽

Primary Effect ◽

Rabbit Reticulocyte Lysate ◽

Eukaryotic Initiation Factor ◽

Ribosomal Subunits ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Reticulocyte Lysate

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Characterization of eukaryotic initiation factor 2 containing two polypeptide chains of Mr = 48,000 and 38,000.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)69556-6 ◽

1981 ◽

Vol 256 (8) ◽

pp. 3988-3994 ◽

Author(s):

A. Chaudhuri ◽

E.A. Stringer ◽

D. Valenzuela ◽

U. Maitra

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Polypeptide Chains

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Characteristics of eukaryotic initiation factor 2 and its subunits.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86161-6 ◽

1980 ◽

Vol 255 (3) ◽

pp. 1189-1193 ◽

Author(s):

M.A. Lloyd ◽

J.C. Osborne ◽

B. Safer ◽

G.M. Powell ◽

W.C. Merrick

Keyword(s):

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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Nonidentity of the 48,000-dalton protein of mRNA-protein particles and the beta subunit of eukaryotic initiation factor 2.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86852-7 ◽

1979 ◽

Vol 254 (17) ◽

pp. 8087-8090

Author(s):

A. Barrieux ◽

M.G. Rosenfeld

Keyword(s):

Beta Subunit ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Protein Particles

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Phosphorylation of Plant Eukaryotic Initiation Factor-2 by the Plant-encoded Double-stranded RNA-dependent Protein Kinase, pPKR, and Inhibition of Protein Synthesisin Vitro

Journal of Biological Chemistry ◽

10.1074/jbc.271.8.4539 ◽

1996 ◽

Vol 271 (8) ◽

pp. 4539-4544 ◽

Author(s):

Jeffrey O. Langland ◽

Lisa A. Langland ◽

Karen S. Browning ◽

Don A. Roth

Keyword(s):

Protein Kinase ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Dependent Protein Kinase ◽

Double Stranded Rna ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2 ◽

Dependent Protein

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The Interaction between Viral Messenger RNA and Eukaryotic Initiation Factor 2, a Protein Involved in Translational Control

Viral Messenger RNA ◽

10.1007/978-1-4613-2585-7_2 ◽

1985 ◽

pp. 21-48

Author(s):

Raymond Kaempfer

Keyword(s):

Translational Control ◽

Messenger Rna ◽

Initiation Factor ◽

Eukaryotic Initiation Factor ◽

Eukaryotic Initiation Factor 2 ◽

Initiation Factor 2

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