Comparison of Cytochrome P450 2C Subfamily Members in Terms of Drug Oxidation Rates and Substrate Inhibition

2012 ◽  
Vol 13 (8) ◽  
pp. 1145-1159 ◽  
Author(s):  
Toshiro Niwa ◽  
Hiroshi Yamazaki
Keyword(s):  
Cytochrome P450 ◽  
Substrate Inhibition ◽  
Oxidation Rates ◽  
Cytochrome P450 2C ◽  
Drug Oxidation

Cytochrome p450 2C (CYP2C) in ischemic heart injury and vascular dysfunctionThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum.

2006 ◽  
Vol 84 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Manreet K. Chehal ◽  
David J. Granville
Keyword(s):  
Cytochrome P450 ◽  
Ischemic Heart ◽  
Epoxyeicosatrienoic Acids ◽  
Special Issue ◽  
Ischemia And Reperfusion Injury ◽  
Current Review ◽  
Cytochrome P450 2C ◽  
Heart Injury ◽  
Selection Of

The cytochrome p450 2C (CYP2C) monooxygenase family is a key player in the generation of epoxyeicosatrienoic acids. It has recently become apparent that CYP plays an important role in cardiovascular physiology and contributes to the pathogenesis of various cardiovascular diseases. In particular, several studies have demonstrated a role for these enzymes in cardiac ischemia and reperfusion injury. The current review summarizes the role of the CYP epoxygenase, CYP2C9, in ischemic heart disease and vascular homeostasis.

Cooperativity ofα-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human

Xenobiotica ◽  
2001 ◽  
Vol 31 (5) ◽  
pp. 265-275 ◽  
Author(s):  
C. Emoto ◽  
H. Yamazaki ◽  
H. Iketaki ◽  
S. Yamasaki ◽  
T. Satoh ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A ◽  
Intestinal Microsomes ◽  
Drug Oxidation

scholarly journals Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa

2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Ina Bergheim ◽  
Christiane Bode ◽  
Alexandr Parlesak
Keyword(s):  
Cytochrome P450 ◽  
Human Colon ◽  
Colon Mucosa ◽  
Cytochrome P450 2C

INSULIN REDUCES THE mRNA ABUNDANCE OF THE PROGESTERONE CATABOLIC ENZYMES CYTOCHROME P450 2C AND 3A IN THE DAIRY COW

2007 ◽  
Vol 77 (Suppl_1) ◽  
pp. 146-146
Author(s):  
Caleb Lemley ◽  
Stephen Butler ◽  
W. Ronald Butler ◽  
Matthew Wilson
Keyword(s):  
Cytochrome P450 ◽  
Dairy Cow ◽  
Mrna Abundance ◽  
Catabolic Enzymes ◽  
Cytochrome P450 2C
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