Neurokinin Peptides and Neurokinin Receptors as Potential Therapeutic Intervention Targets of Basal Ganglia in the Prevention and Treatment of Parkinsons Disease

2004 ◽  
Vol 5 (2) ◽  
pp. 197-206 ◽  
Author(s):  
L.- Chen ◽  
K. Yung ◽  
Y Chan
2012 ◽  
Vol 121 (7) ◽  
pp. 449-456 ◽  
Author(s):  
Samantha R. M. Holmes ◽  
Tricia A. Gudridge ◽  
Jennifer L. Gaudiani ◽  
Philip S. Mehler

Blood ◽  
2010 ◽  
Vol 116 (18) ◽  
pp. 3382-3383 ◽  
Author(s):  
Junia V. Melo ◽  
Duncan R. Hewett

Abstract Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).


2018 ◽  
Vol 19 (7) ◽  
pp. 1953 ◽  
Author(s):  
Mirco Ponzoni ◽  
Fabio Pastorino ◽  
Daniela Di Paolo ◽  
Patrizia Perri ◽  
Chiara Brignole

1975 ◽  
Vol 6 (1-2) ◽  
pp. 87-98 ◽  
Author(s):  
Herbert Benson ◽  
Martha M. Greenwood ◽  
Helen Klemchuk

It is hypothesized that situations requiring continuous behavioral adjustment activate an integrated, hypothalamic response, the emergency reaction. The frequent elicitation of the physiologic changes associated with the emergency reaction has been implicated in the development of diseases such as hypertension. Prevention and treatment of these diseases may be through the use of the relaxation response, an integrated hypothalamic response whose physiologic changes appear to be the counterpart of the emergency reaction. This article describes the basic elements of techniques which elicit the relaxation response and discusses the results of clinical investigations which employ the relaxation response as a therapeutic intervention.


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