Thieno[3,2-c] quinoline Heterocyclic Synthesis and Reactivity part (VI)

Author(s):  
Moustafa A. Gouda ◽  
Ameen A. Abu-Hashem ◽  
Ahmed A. M. Abdelgawad

: The biological and medicinal properties of thieno[3, 2-c] quinoline have prompted enormous research aimed at developing synthetic routes to these systems. This review focuses on the chemical properties associated with this system. The most-reported reactions are Bischler-Napieralski, Suzuki−Miyaura−Schlüter, Pictet-Spengler, Stille coupling. Friedlander and Beckmann rearrangement reaction.

2020 ◽  
Vol 24 (8) ◽  
pp. 817-854
Author(s):  
Anil Kumar ◽  
Nishtha Saxena ◽  
Arti Mehrotra ◽  
Nivedita Srivastava

Quinolone derivatives have attracted considerable attention due to their medicinal properties. This review covers many synthetic routes of quinolones preparation with their antibacterial properties. Detailed study with structure-activity relationship among quinolone derivatives will be helpful in designing new drugs in this field.


2011 ◽  
Vol 7 ◽  
pp. 179-197 ◽  
Author(s):  
Ranjana Aggarwal ◽  
Vinod Kumar ◽  
Rajiv Kumar ◽  
Shiv P Singh

The biological and medicinal properties of 5-aminopyrazoles have prompted enormous research aimed at developing synthetic routes to these heterocyles. This review focuses on the biological properties associated with this system. Various synthetic methods developed up to 2010 for these compounds are described, particularly those that involve the reactions of β-ketonitriles, malononitrile, alkylidenemalononitriles and their derivatives with hydrazines, as well as some novel miscellaneous methods.


2021 ◽  
Vol 1025 ◽  
pp. 110-115
Author(s):  
Mohd Syafik Mohamad Hamdan ◽  
Mohd Azrul Hisham Ismail ◽  
Siti Hajar Noor Shaarani ◽  
Saiful Nizam bin Tajuddin

Agarwood has been used for its fragrance and medicinal properties in Asian culture for centuries. In recent years, agarwood gains its popularity in the west due to its usage in perfume formulation. Unfortunately its supply not meets the augmentation market demand. This is mostly because of depleting nature agarwood reservoir and lack of induction technique that can produce agarwood consistently in the plantation. In this study, we look into a case where artificial inducing technique successfully produced high quality agarwood. To assure its quality, agarwood chip was analysed by Gas Chromatography for its chemical profiles. Discovered compounds were identified as sesquiterpene group which also had been characterized as major agarwood compound listed on previous studies. Few compounds that are detected such as δ-cadinene (0.20%), jinkoh-eremol (22.09%), epi-α-cadinol (4.74%), agarospirol (3.75%) and others. Soil condition that contributes into this agarwood formation; soil analysis on physical properties, chemical properties and nutrients content of the soil have been analyzed. Based on the findings, soil condition is an important factor to successfully induced high quality agarwood.


2010 ◽  
Vol 12 (24) ◽  
pp. 6396 ◽  
Author(s):  
Inés Lezcano-González ◽  
Alejandro Vidal-Moya ◽  
Mercedes Boronat ◽  
Teresa Blasco ◽  
Avelino Corma

2016 ◽  
Vol 128 (6) ◽  
pp. 951-956 ◽  
Author(s):  
MANGFEI YU ◽  
QIAN ZHANG ◽  
JIA WANG ◽  
PENG HUANG ◽  
PENGFEI YAN ◽  
...  

2007 ◽  
Vol 101 (1-2) ◽  
pp. 153-160 ◽  
Author(s):  
B. Bonelli ◽  
L. Forni ◽  
A. Aloise ◽  
J.B. Nagy ◽  
G. Fornasari ◽  
...  

Author(s):  
Lakshmipathy Muthukrishnan

The technological advancements have not only made humans more civilized but have also caused the micro-organisms to develop several survival strategies via antimicrobial resistance to keep pace. Such highly developed microbial systems have been classified as superbugs, exhibiting Trojan-horse mechanism. This uncertain behaviour in microbes has challenged humans to scour around novel moiety to shield themselves from the detrimental effects. One such natural phenomenon that has drawn the attention of researchers is the metal-microbe interaction where microbes were found to be controlled during their interaction with metals. Fine tuning could bestow them with enhanced physico-chemical properties capable of controlling life-threatening micro-organisms. Nano forms of metals (nanoparticles, quantum dots, polymeric nanostructures) exhibiting medicinal properties have been implied toward biomedical theranostics. This chapter highlights the mechanistic antimicrobial resistance and the containment strategy using various nano assemblage highlighting its fabrication and bio-molecular interaction.


2017 ◽  
Vol 7 (12) ◽  
pp. 2512-2523 ◽  
Author(s):  
Yueying Chu ◽  
Guangchao Li ◽  
Ling Huang ◽  
Xianfeng Yi ◽  
Hongqiang Xia ◽  
...  

The influence of Brønsted acid site location on the Beckmann rearrangement reaction over H-ZSM-5 zeolite has been explored.


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