Thyroid Hormones as Potential Early Biomarkers of Exposure to Nonylphenol in Adult Male Lizard (Podarcis sicula)~!2009-10-05~!2010-02-25~!2010-05-17~!

AbstractInsulin was administered to Podarcis sicula in winter, when the thyroid gland is inhibited. The activity of the thyroid increased, plasma concentrations of thyroid hormones and hepatic 5'-monodeiodinase activity (MDA) increased, and thyroid stimulating hormone (TSH) concentrations fell to undetectable values. This result confirms the influence of insulin on the activity of the thyroid gland in the lizard species studied. The mechanisms are still unclear, although there is evidence which leads us to believe that insulin is directly responsible for thyroid activation.

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Is Corticosterone Involved in the Reproductive Processes of the Male Lizard, Podarcis sicula sicula?

Hormones and Behavior ◽

10.1006/hbeh.1994.1009 ◽

1994 ◽

Vol 28 (2) ◽

pp. 117-129 ◽

Cited By ~ 58

Author(s):

Clotilde Manzo ◽

Massimo Zerani ◽

Anna Gobbetti ◽

Maria Maddalena Di Fiore ◽

Francesco Angelini

Keyword(s):

Podarcis Sicula ◽

Male Lizard ◽

Reproductive Processes

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Spermatogenesis, epididymis morphology and plasma sex steroid secretion in the male lizard Podarcis sicula exposed to diuron

Environmental Research ◽

10.1016/j.envres.2008.07.011 ◽

2008 ◽

Vol 108 (2) ◽

pp. 214-223 ◽

Cited By ~ 16

Author(s):

Anna Cardone ◽

Raffaella Comitato ◽

Francesco Angelini

Keyword(s):

Sex Steroid ◽

Podarcis Sicula ◽

Steroid Secretion ◽

Male Lizard

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Thyroid hormone stimulates the Na(+)-PO4 symporter but not the Na(+)-SO4 symporter in renal brush border

AJP Renal Physiology ◽

10.1152/ajprenal.1993.265.2.f323 ◽

1993 ◽

Vol 265 (2) ◽

pp. F323-F326 ◽

Cited By ~ 3

Author(s):

K. W. Beers ◽

T. P. Dousa

Keyword(s):

Thyroid Hormone ◽

Thyroid Hormones ◽

Adult Male ◽

Brush Border ◽

Brush Border Membrane ◽

Male Rats ◽

Similar Degree ◽

Renal Brush Border Membrane ◽

High Phosphate ◽

Renal Brush Border

In our previous studies we established that thyroid hormones [L-thyroxine (T4) or 3,5,3'-triiodothyronine (T3)] elicit an increase in Na(+)-Pi symport in rat and mouse renal brush-border membrane (BBM) vesicles (BBMV), but the Na(+)-coupled symports of other solutes were not influenced. However, a recent report [H. S. Tenenhouse, J. Lee, and N. Harvey. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F420-F426, 1991]claimed that T3 increases to a similar degree both Na(+)-Pi symport and Na(+)-SO4 symport in murine renal BBM. Adult male rats were fed either normal (0.7% Pi; NPD) or high-phosphate (1.4% Pi; HPD) diet and received T3 (0.2 mg/100 g body wt ip) for 3 days before the kidneys were removed, BBMV were prepared, and the transport rates were determined. Although the Na(+)-Pi symport significantly increased (delta = +35%) in both NPD and HPD rats treated with T3, the Na(+)-35SO4 symport and Na(+)-D-[3H]glucose symports were not influenced by T3. Furthermore, treatment of NPD-fed mice with T3 using a similar protocol as rats resulted in a significant increase (delta = +26%) of Na(+)-(Pi)4 symport, but did not alter Na(+)-SO4 symport or Na(+)-glucose symport. Our findings thus document that T3 regulates selectively the Na(+)-Pi symporter in BBM without having any effect on other major divalent anions, such as SO4.

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