scholarly journals Genetics in Keratoconus – What is New?

2017 ◽  
Vol 11 (1) ◽  
pp. 201-210 ◽  
Author(s):  
Sarah Moussa ◽  
Günther Grabner ◽  
Josef Ruckhofer ◽  
Marie Dietrich ◽  
Herbert Reitsamer

Background: Keratoconus is characterized as a bilateral, progressive, non-inflammatory thinning of the cornea resulting in blurred vision due to irregular astigmatism. Keratoconus has a multifactorial etiology, with multiple genetic and environmental components contributing to the disease pathophysiology. Several genomic loci and genes have been identified that highlight the complex molecular etiology of this disease. Conclusion: The review focuses on current knowledge of these genetic risk factors associated with keratoconus.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Khaled K. Abu-Amero ◽  
Abdulrahman M. Al-Muammar ◽  
Altaf A. Kondkar

Keratoconus is a progressive thinning and anterior protrusion of the cornea that results in steepening and distortion of the cornea, altered refractive powers, and reduced vision. Keratoconus has a complex multifactorial etiology, with environmental, behavioral, and multiple genetic components contributing to the disease pathophysiology. Using genome-wide and candidate gene approaches several genomic loci and genes have been identified that highlight the complex molecular etiology of this disease. The review focuses on current knowledge of these genetic risk factors associated with keratoconus.



2020 ◽  
Vol 2020 ◽  
Author(s):  
Dong Yun Kim ◽  
Jun Yong Park


2017 ◽  
Vol 27 ◽  
pp. S873-S874
Author(s):  
S.I. Kim ◽  
H.Y. Choi ◽  
W.J. Lim ◽  
E.J. Kim ◽  
Y.C. Kim ◽  
...  


Author(s):  
M.C. Jiménez-González ◽  
D. Santiago-Germán ◽  
E.F. Castillo-Henkel ◽  
J.A. Alvarado-Moreno ◽  
J. Hernández-Juárez ◽  
...  


2018 ◽  
Vol 235 ◽  
pp. 489-498 ◽  
Author(s):  
Hee-Yeon Choi ◽  
Ga Eun Kim ◽  
Kyoung Ae Kong ◽  
Yu Jin Lee ◽  
Weon-Jeong Lim ◽  
...  


2018 ◽  
Vol 8 (4) ◽  
pp. 593-604 ◽  
Author(s):  
Di Yan ◽  
Richard Ahn ◽  
Stephen Leslie ◽  
Wilson Liao


2002 ◽  
Vol 88 (10) ◽  
pp. 694-697 ◽  
Author(s):  
Yi-Heng Li ◽  
How-Ran Guo ◽  
Wei-Chuan Tsai ◽  
Ting-Hsing Chao ◽  
Jyh-Hong Chen


2004 ◽  
Vol 28 ◽  
pp. 70S-76S ◽  
Author(s):  
Victor Hesselbrock ◽  
Danielle Dick ◽  
Michie Hesselbrock ◽  
Tatiana Foroud ◽  
Marc Schuckit ◽  
...  


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