Benign Notochordal Cell Tumor of the Sacrum with Atypical Imaging Features: The Value of CT Guided Biopsy for Diagnosis

We report a case of a benign notochordal cell tumor (BNCT) of the sacrum with atypical imaging features, which was incidentally discovered in a 74-year-old man undergoing evaluation for progressively worsening hip and back pain. It is important for radiologists, pathologists and orthopedic surgeons to be aware of the diagnosis of BNCT and be familiar with its radiographic features to avoid unnecessary treatment. This case illustrates the advantage of percutaneous computed tomography (CT)-guided biopsy as a minimally invasive technique for definitive diagnosis of a BNCT with atypical imaging features.

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A retrospective analysis of computed tomography guided biopsy in the diagnosis of primary bone tumors

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20171903 ◽

2017 ◽

Vol 3 (3) ◽

pp. 569

Author(s):

Kuriakku Puthur Dominic ◽

Davis Dijoe ◽

Jacob Toms

Keyword(s):

Computed Tomography ◽

Bone Tumors ◽

Diagnostic Efficiency ◽

Ct Guided ◽

Primary Bone Tumor ◽

Primary Bone Tumors ◽

Guided Biopsy ◽

Ct Guided Biopsy ◽

Significant Step ◽

Primary Bone

Background: Primary bone tumors account for a small yet significant number in the total incidence of tumors. Computed tomography (CT) guided percutaneous core biopsy is a novel yet significant step in the approach towards the diagnosis of bone tumors and is increasingly performed by orthopaedic oncologists around the world. This study is aimed to evaluate the diagnostic accuracy of CT guided biopsy in the diagnosis of primary bone tumors. Methods: Patients who underwent CT guided biopsy and subsequent excision for primary bone tumors from January 2008 to July 2015 were analysed. CT guided biopsy results were compared with post-operative histopathological reports to evaluate its sensitivity and specificity.Results: A total of 161 patients were included in the retrospective study. Among them, 147 were true positives, 7 were false negatives, 6 were true negatives and one was false positive. The sensitivity of CT guided biopsy in the diagnosis of primary bone tumor was 95.4 % with specificity of 85.7% with a diagnostic efficiency of 90.5%. The complication rate was 4.3%.Conclusions: CT guided biopsy is a safe, simple and effective procedure to rule out and rule in the diagnosis of primary bone tumors.

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Diagnostic yield and safety of percutaneous CT-guided biopsy of retroperitoneal lesions and analysis of imaging features

Acta Radiologica ◽

10.1177/0284185121990286 ◽

2021 ◽

pp. 028418512199028

Author(s):

Anil Kumar Singh ◽

Zafar Neyaz ◽

Ritu Verma ◽

Anshul Gupta ◽

Richa Mishra ◽

...

Keyword(s):

Diagnostic Yield ◽

Final Diagnosis ◽

Microbiological Analysis ◽

Imaging Features ◽

Imaging Findings ◽

Chi Square ◽

Tissue Samples ◽

Ct Guided ◽

Guided Biopsy ◽

Ct Guided Biopsy

Background Computed tomography (CT)-guided biopsy is emerging as a preferred method for obtaining tissue samples from retroperitoneal lesions due to clear visualization of needle and vessels. Purpose To assess diagnostic yield and safety of CT-guided biopsy of retroperitoneal lesions and compare CT findings in different disease categories. Material and Methods This retrospective analytical study included 86 patients with retroperitoneal lesions who underwent CT-guided biopsy from December 2010 to March 2020. All procedures were performed with co-axial technique and multiple cores were obtained and subjected to histopathology. Additional tests like immunohistochemistry or microbiological analysis were done depending on clinical suspicion. Diagnostic yield calculation and comparison of imaging findings was done by one-way ANOVA, chi-square, and Fisher’s exact tests. Results CT-guided biopsy was technically successful in all cases with a diagnostic yield of 91.9%. Minor complications in the form of small hematomas were seen in two patients. Major disease categories on final diagnosis were lymphoma, tuberculosis, and metastases. A variety of malignant and benign soft-tissue neoplasms were also noted less commonly. With help of immunohistochemistry, lymphoma subtype was established in 88.8% of cases. Addition of microbiological tests like the GeneXpert assay helped in the diagnosis of tuberculosis in some cases. A mass-like appearance and vascular encasement was common in metastatic group and lymphoma. Conclusion Percutaneous CT-guided biopsy is a safe method for the sampling of retroperitoneal lesions with high diagnostic yield. Imaging findings are mostly overlapping; however, some features are more common in a particular disease condition.

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Usefulness of Computed Tomography (CT)-Guided Biopsy for Etiological Diagnosis of Vertebral Destruction Syndrome

Journal of Spine ◽

10.4172/2165-7939.1000295 ◽

2016 ◽

Vol 05 (02) ◽

Author(s):

Alejandro Antonio Reyes-Sánchez ◽

Claudia Obil-Chavarría

Keyword(s):

Computed Tomography ◽

Ct Guided ◽

Etiological Diagnosis ◽

Guided Biopsy ◽

Ct Guided Biopsy

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Results of Percutaneous Computed Tomography-Guided Biopsy of Adrenal Lesions and Spectrum of Computed Tomography Findings

Journal of Clinical Imaging Science ◽

10.25259/jcis_3_2020 ◽

2020 ◽

Vol 10 ◽

pp. 16

Author(s):

Sriharsha Gunna ◽

Zafar Neyaz ◽

Eesh Bhatia ◽

Rungmei S Marak ◽

Richa Mishra ◽

...

Keyword(s):

Computed Tomography ◽

Multidetector Ct ◽

Diagnostic Yield ◽

Major Complication ◽

Malignant Neoplasms ◽

Safe Procedure ◽

Ct Scanner ◽

Ct Guided ◽

Guided Biopsy ◽

Ct Guided Biopsy

Objective: Adrenal enlargement occurs in various conditions such as infections, benign, and malignant neoplasms. Percutaneous computed tomography (CT)-guided adrenal biopsy is a safe method for obtaining tissue specimen in cases where diagnosis cannot be established on imaging and biochemical grounds. The study aims to evaluate diagnostic yield, accuracy, and complications of percutaneous CT-guided adrenal biopsies. Furthermore, CT findings of various adrenal lesions have been described. Materials and Methods: Data of CT-guided adrenal biopsies performed from September 2009 to May 2019 were analyzed. Biopsies were performed on a 64-slice or a 128-slice multidetector CT scanner using a coaxial technique. Pathological and microbiological reports were retrieved from the hospital information system. Clinical details were obtained from clinical case records. Results: CT-guided adrenal biopsies were performed in 48 patients, 37 males and 11 females. Adrenal insufficiency was present in 31 (64%) cases and bilateral adrenal glands were affected in 35 (73%). Biopsy yielded a diagnosis in 35 cases (72.9%). The final diagnosis was achieved in 43 (90%) cases. Combined accuracy of CT-guided biopsy for identifying malignancy and infection was 88.3%. Adrenal histoplasmosis (AH) was the most common entity diagnosed (44%). After combining histopathology and microbiology results, the sensitivity for diagnosing AH was 100%. One (2%) patient had a major complication in the form of intra-abdominal hemorrhage requiring transfusion. Local hematoma and mild stable pneumothorax were noted in one patient each. Conclusion: Percutaneous CT-guided biopsy is a safe procedure for the diagnosis of adrenal lesions. It has good accuracy for diagnosing adrenal conditions such as infections and malignancies. However, the specific diagnosis of benign adrenal lesions was difficult to make. AH, tuberculosis, and metastasis have overlapping imaging findings.

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Primary Adrenal Tuberculosis: Role of Computed Tomography and CT-Guided Biopsy in Diagnosis

Urologia Internationalis ◽

10.1159/000091637 ◽

2006 ◽

Vol 76 (3) ◽

pp. 285-287 ◽

Cited By ~ 6

Author(s):

E.N. Liatsikos ◽

C.P. Kalogeropoulou ◽

Z. Papathanassiou ◽

I. Tsota ◽

A. Athanasopoulos ◽

...

Keyword(s):

Computed Tomography ◽

Ct Guided ◽

Guided Biopsy ◽

Ct Guided Biopsy

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Computed Tomography-Guided Biopsy Assisted by 18F-FDG Coincidence Imaging for Solid Tumours

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2019.2632 ◽

2019 ◽

Vol 9 (2) ◽

pp. 366-370

Author(s):

Feng Chen ◽

Yunlei Pan ◽

Tianzeng Lin ◽

Shan Chen ◽

Yuan Hong

Keyword(s):

Computed Tomography ◽

Solid Tumour ◽

Final Diagnosis ◽

Solid Tumours ◽

Ct Guided ◽

Guided Biopsy ◽

Needle Position ◽

Significant Difference ◽

Ct Guided Biopsy ◽

Coincidence Imaging

Objective: Early diagnosis of solid tumour is the key to making treatment plans. The traditional computed tomography (CT)-guided percutaneous biopsy often makes it difficult to determine the puncture point. The aim of this study is to analyze the collaborative application value of CT-guided biopsy assisted by 18F-FDG coincidence imaging for solid tumours. Methods: A retrospective analysis of 15 patients who underwent routine radiological examination can not form a correct diagnosis on body solid tumour. The needle was introduced under CT guidance in a step-by-step technique and correct needle position in the centre of FDG high concentration area in coincidence imaging. The biopsy specimens were examined under light microscopy and immunofluorescence. Result: All the lesions were successfully punctured, and the final diagnosis was malignant in 14 cases and benign in 1 cases. The sensitivity of CT-guided biopsy assisted by coincidence imaging was 92.9% (13/14), and the specificity was 100% (1/1). Compared with clinical final diagnosis, there was no significant difference between the two groups (P >0.05). Two cases of lung biopsy patients had a small amount of blood in sputum after operation. Conclusion: The CT-guided biopsy assisted by 18F-FDG coincidence imaging may improve the diagnostic capability, especially in cases when a definitive diagnosis by imaging alone is difficult to make.

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