Type 2 Diabetes Mellitus Related to Decreased Peripheral and Respiratory Muscle Strength in sarcopenic Thai Elderly

2021 ◽  
Vol 14 ◽  
Author(s):  
Kornanong Yuenyongchaiwat ◽  
Rumpa Boonsinsukh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Quadriceps Muscle ◽  
Community Dwelling ◽  
Respiratory Muscle Strength ◽  
Peripheral Muscle

Background: Age is related to a decline in muscle mass and physical function in respiratory and peripheral muscle strength, leading to mobility and mortality. In addition, older people have suffered from one or multiple chronic conditions, particularly type 2 diabetes mellitus (type 2DM). However, few studies have reported the relationship between sarcopenic elderly and respiratory and peripheral muscle strengths in type 2DM. Objective: To explore the prevalence of sarcopenia in type 2DM elderly people among community dwelling patients and the relationships with peripheral and respiratory muscle loss in sarcopenic type 2DM older patients. Methods: A total of 330 older individuals were recruited from community-dwelling centers. Respiratory muscle and quadriceps muscle were assessed. According to the defined criteria for sarcopenia (defined by Asian Working Group for Sarcopenia), muscle mass, gait speed (six-meter walk test) and handgrip strength were examined. Results: Of 330 older people, 82 volunteers had a history of type 2DM. Participants with type 2DM had a risk for sarcopenia (odds ratio= 2.324, 95% CI=1.251-4.317). The prevalence of sarcopenia was 25.61% among older participants with type 2DM. In addition, decreased respiratory muscle strength and quadriceps muscle strength was observed in type 2DM with sarcopenia compared to type 2DM with non-sarcopenia. These relationships also remained after controlling for age and sex. Conclusion: sarcopenia in type 2DM leads to a decrease in respiratory muscle and peripheral muscle strength.

scholarly journals The Influence of Clinically Diagnosed Neuropathy on Respiratory Muscle Strength in Type 2 Diabetes Mellitus

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Birgit L. M. Van Eetvelde ◽  
Dirk Cambier ◽  
Karsten Vanden Wyngaert ◽  
Bert Celie ◽  
Patrick Calders
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Muscle Strength ◽  
Physical Performance ◽  
Respiratory Muscle ◽  
Healthy Controls ◽  
Respiratory Muscle Strength ◽  
Peripheral Muscle

Objectives. This cross-sectional study investigated the influence of clinically diagnosed neuropathy (cdNP) on respiratory muscle strength in patients with type 2 diabetes mellitus (T2DM). Methods. 110 T2DM patients and 35 nondiabetic healthy controls (≥60 years) were allocated to one of three groups depending on the presence of cdNP: T2DM without cdNP (D−; n=28), T2DM with cdNP (D+; n=82), and controls without cdNP (C; n=35). Clinical neurological diagnostic examination consisted of Vibration Perception Threshold and Diabetic Neuropathy Symptom score. Respiratory muscle strength was registered by maximal Inspiratory and Expiratory Pressures (PImax and PEmax), and respiratory function by Peak Expiratory Flow (PEF). Isometric Handgrip Strength and Short Physical Performance Battery were used to evaluate peripheral skeletal muscle strength and physical performance. Univariate analysis of covariance was used with age, level of physical activity, and body mass index as covariates. Results. PImax, PEmax, and PEF were higher in C compared to D− and D+. Exploring more in detail, PImax, PEmax, and PEF were significantly lower in D+ compared to C. PEmax and PEF were also significantly lower in D− versus C. Measures of peripheral muscle strength and physical performance showed less associations with cdNP and T2DM. Conclusions. The presence of cdNP affects respiratory muscle strength in T2DM patients compared to healthy controls. Both cdNP and diabetes in themselves showed a distinctive impact on respiratory muscle strength and function; however, an accumulating effect could not be ascertained in this study. As commonly used measures of peripheral muscle strength and physical performance seemed to be less affected at the given time, the integration of PImax, PEmax, and PEF measurements in the assessment of respiratory muscle weakness could be of added value in the (early) screening for neuropathy in patients with T2DM.

Reduced respiratory muscle strength and endurance in type 2 diabetes mellitus

2012 ◽  
Vol 28 (4) ◽  
pp. 370-375 ◽  
Author(s):  
Leonello Fuso ◽  
Dario Pitocco ◽  
Anna Longobardi ◽  
Francesco Zaccardi ◽  
Chiara Contu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength

scholarly journals Pre- and postoperative respiratory muscle strength, body mass index and fasting glucose profile of patients with type 2 diabetes mellitus submitted to metabolic surgery

2020 ◽  
Vol 33 ◽  
Author(s):  
Ariana de Melo Tosta ◽  
Marisa de Carvalho Borges ◽  
Élida Mara Carneiro da Silva ◽  
Alex Augusto da Silva ◽  
Eduardo Crema
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Muscle Strength ◽  
Postoperative Period ◽  
Metabolic Surgery ◽  
Respiratory Muscle ◽  
Fasting Glucose ◽  
Respiratory Muscle Strength

Abstract Introduction: The lung is considered a target organ in diabetes mellitus as a consequence of alterations secondary to chronic hyperglycemia that compromise respiratory muscle strength. Metabolic surgery for improving diabetes mellitus has beneficial effects on weight loss and glucose metabolism. Objective: The objective of this study was to evaluate the respiratory muscle strength, assessed by MIP and MEP, body mass index (BMI) and fasting glucose profile of patients with type 2 diabetes mellitus before and after metabolic surgery without gastric resection. Method: Seventeen patients with type 2 diabetes mellitus participated in the study. The participants had a mean age of 44.8 ± 11.81 years. Results: The results showed a significant decrease of MEP values in the immediate postoperative period when compared to the preoperative period (p=0.001), while no significant results were obtained for MIP. Regarding BMI and fasting glucose, significant weight loss and a significant reduction in fasting glucose levels were observed in the late postoperative period (p=0.006 and p=0.007, respectively). Conclusion: The MIP and MEP were reestablished and satisfactory results were obtained for BMI and fasting glucose in the late postoperative period. Further studies are needed to monitor patients in the pre- and postoperative period of metabolic surgery, identifying complications and acting on the care and recovery of these patients.

scholarly journals Association between muscle strength and type 2 diabetes mellitus in adults in Korea

Medicine ◽  
2018 ◽  
Vol 97 (23) ◽  
pp. e10984 ◽  
Author(s):  
Mee-Ri Lee ◽  
Sung Min Jung ◽  
Hyuk Bang ◽  
Hwa Sung Kim ◽  
Yong Bae Kim
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Muscle Strength

scholarly journals Falls among Older Adults with Type 2 Diabetes Mellitus with Peripheral Neuropathy

2021 ◽  
Vol 72 (2) ◽  
pp. 92-98
Author(s):  
Mantana Vongsirinavarat
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Muscle Strength ◽  
Clinical Test ◽  
Balance Performance ◽  
Functional Reach Test ◽  
History Of

Objective: The high incidence and prevalence of falls among older people with type 2 diabetes mellitus (ODM) have been documented. The risk factors of falls among ODM were identified as poor diabetic control, diabetic peripheral neuropathy (DPN) and balance impairment. This study aimed to investigate the contribution of DPN to history of falls. The differences of balance performance and lower limb muscle strength among ODM with and without DPN were also explored. Methods: This cross-sectional study interviewed 112 ODM for their falls occurrences within the previous 6 months. DPN was determined by the score of the Michigan Neuropathy Screening Instrument. Balance performance tests included Clinical Test of Sensory Interaction and Balance (mCTSIB), Functional Reach Test (FRT) and Timed Up and Go Test (TUG). Leg muscle strength was also measured. The logistic regression analysis was performed. Results: The history of falls was reported 30.6% of ODM with DPN and 10.4% of ODM without DPN. Presenting of DPN influenced falls with odds ratio of 3.46 among ODM. Differences were found of mCTSIB in the condition of eyes closed on firm and foam surfaces, FRT, and TUG between those with and without DPN. Knee extensor strength differed between those with and without DPN. Conclusion: DPN was more prominent among fallers. Balance performance and leg strength were lower in ones with DPN. Falls prevention programs including balance training and therapeutic exercise to improve balance performance and muscle strength should be emphasized among ODM, especially before the onset of DPN.

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