Preparation and Characterization of Bifunctional Nanoparticles of Vitamin E TPGS-emulsified PLGA-PEG-FOL Containing Deferasirox

2015 ◽  
Vol 4 (2) ◽  
pp. 80-87 ◽  
Author(s):  
Mina Mir ◽  
Pedram Ebrahimnejad
Keyword(s):  
Vitamin E ◽  
Vitamin E Tpgs

scholarly journals Preparation and characterization of Alendronate depot microspheres based on novel poly(-ε-caprolactone)/Vitamin E TPGS copolymers

2019 ◽  
Vol 1 ◽  
pp. 100014 ◽  
Author(s):  
Christina Koulouktsi ◽  
Stavroula Nanaki ◽  
Panagiotis Barmpalexis ◽  
Margaritis Kostoglou ◽  
Dimitrios Bikiaris
Keyword(s):  
Vitamin E ◽  
Vitamin E Tpgs

Characterization of solid dispersions of itraconazole and vitamin E TPGS prepared by microwave technology

2010 ◽  
Vol 2 (2) ◽  
pp. 237-246 ◽  
Author(s):  
Mariarosa Moneghini ◽  
Nicola De Zordi ◽  
Dario Solinas ◽  
Stefano Macchiavelli ◽  
Francesco Princivalle
Keyword(s):  
Vitamin E ◽  
Solid Dispersions ◽  
Microwave Technology ◽  
Vitamin E Tpgs

Fabrication and Characterization of Vitamin E TPGS Loaded Silk Fibroin/Hyaluronic Acid Nanofibrous Scaffolds

2013 ◽  
Vol 721 ◽  
pp. 274-277
Author(s):  
Li Li Ji ◽  
Qiao Ling Li ◽  
Zeng Hu Yang ◽  
Wei Jing Hu ◽  
Kui Hua Zhang
Keyword(s):  
Hyaluronic Acid ◽  
Vitamin E ◽  
Silk Fibroin ◽  
Ethanol Vapor ◽  
Random Coil ◽  
Burst Release ◽  
Nanofibrous Scaffolds ◽  
Vitamin E Tpgs ◽  
Polyethylene Glycol 1000 ◽  
Β Sheet

Vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate (VE TPGS) loaded silk fibroin (SF)/ hyaluronic acid (HA) nanofibrous scaffolds were fabricated by means of electrospinning to biomimic the natural extracellular matrix. Scanning electronic microscopy (SEM) results indicated that electrospun VE TPGS loaded SF/HA nanofibers were ribbon-shaped, the width of nanofibers decreased slightly with the addition of VE TPGS to SF/HA blended solutions. Fourier transform infrared (FTIR) spectroscopy and Wide-angle X-ray diffraction (WAXD) curves revealed that VE TPGS did not induce SF conformation from random coil to β-sheet. SF conformation converted from random coil to β-sheet after being treated with 75% ethanol vapor. In vitro release studies confirmed VE TPGS had no obvious burst release and present good release behavior.

Preparation and Characterization of Aqueous Vitamin E/Soluplus® Dispersions for Film Coating Applications

2021 ◽  
pp. 1-11
Author(s):  
Ahmad Salawi ◽  
Jafrin Jobayer Sonju ◽  
Mohammad M. Kamal ◽  
Ahmed Abu-Fayyad ◽  
Turki Al Hagbani ◽  
...  
Keyword(s):  
Vitamin E ◽  
Film Coating

scholarly journals Liquid crystalline systems containing Vitamin E TPGS for the controlled transdermal nicotine delivery

2016 ◽  
Vol 52 (1) ◽  
pp. 191-200 ◽  
Author(s):  
Lívia Neves Borgheti-Cardoso ◽  
Fabiana Testa Moura de Carvalho Vicentini ◽  
Tais Gratieri ◽  
Maria Vitória Lopes Badra Bentley
Keyword(s):  
Vitamin E ◽  
Liquid Crystalline ◽  
Visual Analysis ◽  
Skin Permeation ◽  
Skin Irritation ◽  
Cubic Phase ◽  
Nicotine Delivery ◽  
Vitamin E Tpgs ◽  
Transdermal Nicotine

ABSTRACT Transdermal nicotine patches have been used in smoking cessation therapy, suggested for the treatment of skin disorders with eosinophilic infiltration and have been found to improve attention performance in patients with Alzheimer's disease and age-associated memory impairment. However, skin irritation with extended patch use is still a problem. The aim of this work was to develop a simple to prepare liquid crystalline system containing vitamin E TPGS that would be able to control nicotine delivery and reduce irritation and sensitization problems. The liquid crystalline phases were macroscopically characterized by visual analysis and examined microscopically under a polarized light microscope. Topical and transdermal delivery of nicotine were investigated in vitro using porcine ear skin mounted on a Franz diffusion cell. Nicotine skin permeation from the developed cubic phase followed zero-order kinetics (r = 0.993) and was significantly enhanced after 12 h when compared to the control formulation (nicotine solution) (p < 0.05) (138.86 ± 20.44 and 64.91 ± 4.06 μg/cm2, respectively). Cubic phase was also able to target viable skin layers in comparison to control solution (8.18 ± 1.89 and 2.63 ± 2.51 μg/cm2, respectively). Further studies to evaluate skin sensitization and irritation are now necessary.

Targeting vitamin E TPGS–cantharidin conjugate nanoparticles for colorectal cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (66) ◽  
pp. 53846-53856 ◽  
Author(s):  
Shihou Sheng ◽  
Tao Zhang ◽  
Shijie Li ◽  
Jun Wei ◽  
Guangjun Xu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Drug Delivery ◽  
Vitamin E ◽  
Chinese Medicine ◽  
Side Effects ◽  
Cancer Therapy ◽  
Traditional Chinese Medicine ◽  
Drug Efficacy ◽  
Vitamin E Tpgs ◽  
Colorectal Cancer Cells

A traditional Chinese medicine cantharidin which was previously found to be effective on colorectal cancer cells was translated into nanoparticles for drug delivery to reduce its side effects and enhance its drug efficacy.

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