Ultrasonic Evaluation of Common Carotid Intima-Media Thickness (IMT) Influence of Local Plaque on the Relationship Between IMT and Age

Large blood pressure variability (BPV) will not only harm the target organ but also increase the possibility of the cardiovascular events. Since the damage of vascular system always leads to the alteration of the carotid wall, the structure and function of the carotid artery have been extensively examined in previous studies. In this work we conduct a study (60 subjects, aged 33–79) to evaluate the relationship between BPV and carotid intima-media thickness (IMT) in Shenzhen, which is one large city in the southern area of China. In our study, the blood pressure (BP) was collected using the 24 h ambulatory BP monitoring, and the BPV was evaluated using standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) during 24 h, daytime and nighttime. All the IMT measurements are collected by ultrasound. The results show that both the daytime, and 24 h systolic BPV evaluated by three indices are positively associated with IMT. Among them, daytime systolic BPV evaluated with ARV is the best variable to represent the increasing of carotid IMT. In addition, after adjusting by age, sex, smoking, hypertension, and mean BP and PP values, 24 h diastolic BPV evaluated with SD also presents the favorable performance.

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The Relationship between the Korean Occupational Stress Scale and Carotid Intima-Media Thickness among Male Firefighters

Korean Journal of Occupational and Environmental Medicine ◽

10.35371/kjoem.2012.24.4.420 ◽

2012 ◽

Vol 24 (4) ◽

pp. 420

Author(s):

Sang-Jun Park ◽

Dong-Kyun Lim ◽

Mi-Young Lee ◽

In-Sung Chung

Keyword(s):

Occupational Stress ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Stress Scale ◽

Media Thickness ◽

The Relationship

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Abstract 718: The Association of Erectile Dysfunction with Carotid Intima Media Thickness and Endothelial Dysfunction: A Meta-Analysis

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvb.35.suppl_1.718 ◽

2015 ◽

Vol 35 (suppl_1) ◽

Author(s):

Bryan D Vo ◽

Ehimen Aneni ◽

Ebenezer Oni ◽

Wazim Maziak ◽

Theodore Feldman ◽

...

Keyword(s):

Erectile Dysfunction ◽

Meta Analysis ◽

Random Effect ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Individual Participant Data ◽

Media Thickness ◽

Individual Participant ◽

The Relationship ◽

Random Effect Models

Introduction: A recent meta-analysis showed that erectile dysfunction (ED) was associated with elevated cardiovascular disease (CVD) mortality. However, findings from studies examining the relationship between ED and sub-clinical CVD have been conflicting. This study summarizes the current evidence related to the association of ED and vascular disease as measured by flow mediated dilation (FMD) of the endothelium and carotid intima media thickness (CIMT). Methods: We searched multiple internet databases for published literature on studies assessing the association of ED and FMD, and CIMT between 1964 and 2014. A total of 11 studies met the inclusion criteria for examining the association between ED and FMD, while 7 studies met criteria for assessing the association with CIMT. Fixed-effect and random-effect models were used to assess and compare the standardized mean difference (SMD) of FMD and CIMT between persons with and without ED. Results: From a total of 795 individual participant data (590 with and 205 without ED), persons with ED had a 0.66mm (0.49, 0.83) increase in CIMT by fixed effects model or 0.67mm (0.44, 0.90) by random effects model compared to those without ED. Similarly, from 1055 individual participant data (536 with and 419 without ED), ED was associated with a significant reduction in FMD by both fixed effect (-1.10% (95% CI: -2.10, -0.95)) and random effect models (-1.53% (95% CI: -2.10, -0.95)). There was significant heterogeneity among studies assessing the relationship between ED and FMD (I2 = 93.2%, p<0.001) but not among those comparing CIMT among persons with ED (I2 = 43.5% p=0.09). Conclusion: This study confirms that ED is associated with both worsening endothelial function and increased CIMT. Thus, worsening vascular function may be a pathogenic mechanism for increased CVD morbidity and mortality in persons with ED. A diagnosis of ED should prompt a thorough CV work-up and aggressive preventive management.

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