Magnetic resonance imaging findings and its association to electroencephalogram in children with partial epilepsy (Preprint)

Preschool Children ◽

Magnetic Resonance ◽

Brain Mri ◽

Partial Epilepsy ◽

Small Sample ◽

Normal Brain ◽

Resonance Imaging ◽

Normal Children ◽

Eeg Abnormalities

BACKGROUND It is important to identify the neuroimaging features that are associated with partial epilepsy in preschool children. Advances in technology recently to localize focal epileptogenic lesions, especially that of high-resolution structural imaging with magnetic resonance imaging (MRI). The recommendation that electroencephalography (EEG) should be gold criteria and that M.R.I should be optional has been questioned. OBJECTIVE The present study aims to to explore the brain lesions on MRI and its association to electroencephalogram in children with partial epilepsy. METHODS The present study was conducted among 112 preschool children with history of partial seizures. All patients underwent EEG and brain MRI. The epileptogenic lesions were identified on the basis of the signal intensities and morphological abnormalities seen on MRI. The correlation between MRI and EEG abnormalities was explored using a chi-square test. RESULTS Abnormal MRI were found in 34.8% (n = 39) of the sample. The EEG and MRI agreed with respect to classify into abnormal or normal in 48.2% (n = 54). Of the 27 patients with a normal EEG, six (22.2%) were seen to have an abnormal MRI. CONCLUSIONS A number of MRI abnormalities was found in our study of otherwise normal children, although the correlation between these results was not clear. Follow-up of these children will help us identify the important abnormalities. Despite of small sample, our results showed that a normal E.E.G findings does not predict a normal brain MRI in children with partial epilepsy.

Magnetic resonance imaging of the normal brain in a newborn dromedary camel

The Veterinary Journal ◽

10.1016/j.tvjl.2003.06.001 ◽

2004 ◽

Vol 168 (3) ◽

pp. 353-357 ◽

Author(s):

Alberto Arencibia ◽

Miguel A. Rivero ◽

Juan A. Ramı́rez ◽

Francisco Gil ◽

Carlos Gutierrez ◽

...

Keyword(s):

Magnetic Resonance ◽

Dromedary Camel ◽

Normal Brain ◽

Resonance Imaging

Yield of Brain Magnetic Resonance Imaging in Epilepsy Diagnosis from 1998 to 2020: A Large Retrospective Cohort Study

Neuropediatrics ◽

10.1055/s-0041-1732325 ◽

2021 ◽

Author(s):

Tomer Stern ◽

Liora Kornreich ◽

Hadassa Goldberg

Keyword(s):

Magnetic Resonance ◽

Focal Epilepsy ◽

Brain Mri ◽

Infantile Spasms ◽

Mesial Temporal Sclerosis ◽

Resonance Imaging ◽

Brain Abnormalities ◽

Epilepsy Diagnosis

Abstract Background We aimed to find the clinical significance of brain abnormalities on magnetic resonance imaging (MRI) in epilepsy and the lateralization of these findings with electroencephalogram (EEG). Methods We retrospectively analyzed the results of all EEGs and brain MRIs of 600 consecutive epilepsy patients from 1998 to 2020. Results Data were available for 563 cases (267 females). Ninety percent of the patients were 18 years old or younger. A total of 345 patients (61.3%) had focal epilepsy, 180 (32%), generalized, and 38 (6.7%), inconclusive. In 187 (33.2%), the first MRI was abnormal and in 81 (out of 108 repeated MRI), the second was pathological. The most frequent brain abnormalities were cortical dysplasia in 41 (18.1%), other structural abnormalities in 25 (11%), various phacomatoses in 23 (10.1%), and mesial temporal sclerosis in 17 (7.5%). Among 226 patients with abnormal MRI, 171 (75.6%) had focal epilepsy when compared with 36 (15.9%) with generalized epilepsy (p <0.001). In 121 patients (53.5%), the result of the abnormal MRI contributed significantly to the understanding of the epilepsy etiology. The side of abnormality was lateralized to the EEG focus in 120 cases (53%); in 10/15 cases with infantile spasms (66%), MRI was significantly abnormal. In 33, in whom the first MRI was normal, a second MRI revealed a significant abnormality. Conclusion Brain MRI is an important tool in epilepsy diagnosis, mainly in focal seizures and infantile spasms. A repeat MRI is mandatory in intractable focal cases to improve the yield of this test.

U mỡ trong xương bướm: một trường hợp hiếm gặp

Journal of Clinical Medicine- Hue Central Hospital ◽

10.38103/jcmhch.2021.71.6 ◽

2021 ◽

Author(s):

Thu Hien Trinh Thi

Keyword(s):

Magnetic Resonance ◽

Rare Case ◽

Imaging Techniques ◽

Brain Mri ◽

Sphenoid Bone ◽

Resonance Imaging ◽

Large Tumor ◽

Intraosseous Lipoma

TÓM TẮT U mỡ trong xương là khối u lành tính hiếm gặp, thường gặp ở các xương dẹt, hiếm gặp ở xương nền sọ, đặc biệt là xương bướm. Trong đa số các trường hợp, u mỡ trong xương bướm thường được phát hiện tình cờ qua chụp cắt lớp vi tinh (CLVT) hoặc cộng hưởng từ (CHT) sọ não. Đây là một khối u phát triển chậm, ít gây ra triệu chứng, một số trường hợp gây triệu chứng khi khối u to chèn ép vào cấu trúc lân cận như tuyến yên hoặc dây thần kinh thị. Trong bài này, chúng tôi báo cáo một trường hợp u mỡ trong xương bướm không triệu chứng được phát hiện tình cờ và được chẩn đoán dựa vào phim chụp cộng hưởng từ sọ não. Bệnh nhân được khuyến nghị theo dõi định kỳ bằng cộng hưởng từ mà không phải tiến hành bất kỳ phương pháp điều trị nào. Từ khóa: U mỡ, xương bướm, MRI, cộng hưởng từ sọ não, chẩn đoán hình ảnh. ABSTRACT INTRAOSSEOUS LIPOMA OF SPHENOID BONE: A RARE CASE REVIEW Intraosseous lipoma is very rare, usually benign tumor of flat bones. The incidence of an intraosseous lipomalocated basal skull bones is extremely rare, especially in sphenoid bone. Radiological imaging techniques such as magnetic resonance imaging (MRI) and computed tomography (CT) are used to detect the intraosseous lipoma by accident. These tumors are slow growing and usually asymptomatic, in some cases causing symptoms when the large tumor presses on nearby structures such as pituitary gland or the optic nerve. We present a rare case of lipomaof the sphenoid bone discovered incidentally with brain magnetic resonance imaging. The patient has been followed-up by magnetic resonance imaging without the need for surgery. Keywords: Intraosseous lipoma, sphenoid bone, MRI, brain MRI, diagnostic radiology

Perfusion Magnetic Resonance Imaging to Assess Brain Tumor Responses to New Therapies

Cancer Control ◽

10.1177/107327489800500202 ◽

1998 ◽

Vol 5 (2) ◽

pp. 115-123 ◽

Cited By ~ 16

Author(s):

Michael H. Lev ◽

Fred Hochberg

Keyword(s):

Brain Tumor ◽

Magnetic Resonance ◽

Imaging Techniques ◽

Perfusion Mri ◽

Perfusion Magnetic Resonance Imaging ◽

Normal Brain ◽

Resonance Imaging ◽

New Therapies ◽

Magnetic Resonance Imaging Mri

Background: Although magnetic resonance imaging (MRI) is effective in detecting the location of intracranial tumors, new imaging techniques have been studied that may enhance the specificity for the prediction of histologic grade of tumor and for the distinction between recurrence and tumor necrosis associated with cancer therapy. Methods: The authors review their experience and that of others on the use of perfusion magnetic resonance imaging to evaluate responses of brain tumors to new therapies. Results: Functional imaging techniques that can distinguish tumor from normal brain tissue using physiological parameters. These new approaches provide maps of tumor perfusion to monitor the effects of novel compounds that restrict tumor angiogenesis. Conclusions: Perfusion MRI not only may be as effective as radionuclide-based techniques in sensitivity and specificity in assessing brain tumor responses to new therapies, but also may offer higher resolution and convenient co-registration with conventional MRI, as well as time- and cost-effectiveness. Further study is needed to determine the role of perfusion MRI in assessing brain tumor responses to new therapies.

Maple syrup urine disease: magnetic resonance imaging findings in three patients

Journal of the Pakistan Medical Association ◽

10.47391/jpma.1341 ◽

2021 ◽

pp. 1-11

Author(s):

Aliya Allahwala ◽

Sibtain Ahmed ◽

Bushra Afroze

Keyword(s):

Amino Acids ◽

Magnetic Resonance ◽

Maple Syrup Urine Disease ◽

Brain Mri ◽

Resonance Imaging ◽

Maple Syrup ◽

Urine Disease ◽

Branched Chain

Abstract Maple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disorder, caused by branched-chain alpha-ketoacid dehydrogenase (BCKD) deficiency, leading to toxic accumulation of branched-chain amino acids (BCAAs) including leucine, isoleucine and valine and their corresponding ?-ketoacids. The diagnosis of MSUD is based on elevated BCAAs and allo-isoleucine in plasma, and branched-chain hydroxyacids and ketoacids in urine. The identification of alloisoleucine >5 µmol/L is considered pathognomonic. Moreover, brain magnetic resonance imaging (MRI) showing atypical signal intensity and oedema is characteristic of MSUD. Recognition of the classical neuro-radiological findings of MSUD is particularly useful in local settings as many healthcare facilities lack the resources to measure Plasma Amino Acids (PAA). We report three cases of MSUD, in whom the disorder was strongly suspected at presentation, based on classical brain MRI findings, which was urgently confirmed by PAA analysis Continuous...

Proximal hyper-intense vessel sign on initial FLAIR MRI in hyper-acute middle cerebral artery ischemic stroke: a retrospective observational study

Acta Radiologica ◽

10.1177/0284185120946718 ◽

2020 ◽

pp. 028418512094671 ◽

Author(s):

Dong Hyuk Shin ◽

Sang Kuk Han ◽

Jang Hee Lee ◽

Pil Cho Choi ◽

Sang O Park ◽

...

Keyword(s):

Magnetic Resonance ◽

Middle Cerebral Artery ◽

Cerebral Artery ◽

Cerebral Arteries ◽

Brain Mri ◽

Large Vessel ◽

Resonance Imaging ◽

Vessel Occlusion ◽

Vessel Stenosis

Background A hyper-intense vessel sign on fluid attenuated inversion recovery magnetic resonance imaging (FHV) represents slow blood flow in the cerebral arteries. Purpose To investigate the relationship between the proximal FHV (pFHV) on initial magnetic resonance imaging (MRI) and the status of the culprit vessel (stenosis, obstruction) in hyper-acute strokes affecting the territory of the middle cerebral artery (MCA). Material and Methods The study participants consisted of 105 patients presenting to the emergency department (ED) with acute MCA infarction within 4.5 h of onset of symptoms. Patients underwent brain MRI within 45 min of arrival at the ED and angiography within 2 h of arrival. Culprit vessel status and presence of a pFHV on initial MRI were investigated retrospectively. Results The pFHV was observed in 71/105 (67.6%) patients who presented with a hyper-acute MCA infarction. All patients with hyper-acute MCA infarction caused by internal carotid artery (90.6% caused by M1 occlusion, 92.9% caused by M2 occlusion) showed a pFHV on initial MRI. After logistic regression analysis, the presence of a pFHV showed significant positive correlation with large vessel occlusion (adjusted odds ratio [OR] 34.533, 95% confidence interval [CI] 9.781–121.926; P < 0.001). A pFHV was not associated with severe large vessel stenosis. Conclusion A pFHV is independently representative of the acute occlusion of intervention-eligible proximal arteries within the territory of the MCA. If a patient with a hyper-acute MCA infarction shows a pFHV, aggressive flow augmentation strategies and early activation of intervention team should be warranted for best patient outcome.

Can we evaluate cranial aneurysms on conventional brain magnetic resonance imaging?

Journal of Neurosciences in Rural Practice ◽

10.4103/0976-3147.165425 ◽

2016 ◽

Vol 7 (01) ◽

pp. 83-86 ◽

Author(s):

Emine Caliskan ◽

Yeliz Pekcevik ◽

Adnan Kaya

Keyword(s):

Magnetic Resonance ◽

Characteristic Curve ◽

Brain Mri ◽

Kappa Statistics ◽

Resonance Imaging ◽

Vascular Structures ◽

Magnetic Resonance Imaging Mri ◽

Age Range

ABSTRACT Purpose: To evaluate the contribution of conventional brain magnetic resonance imaging (MRI) for the determination of intracranial aneurysms. Materials and Methods: Brain MRI and computed tomography angiography (CTA) of 45 patients (29 women and 16 men; age range, 32–80 years) with aneurysm were analyzed. A comparison was made between brain MRI and CTA based on size and presence of aneurysm. The comparisons between MRI and CTA were investigated through Bland-Altman graphics, receiver operating characteristic curve, and Kappa statistics. Results: Fifty-seven aneurysms were evaluated. Forty-five percent of 57 aneurysms on CTA were detected on conventional brain MRI. A significant correlation was found between CTA and brain MRI in the diagnosis of aneurysm (P < 0.05). In an analysis of the size measurement, a significant correlation was observed between CTA and brain MRI. Seventy-seven percent of aneurysms <4 mm was not detected and the efficiency of MRI in the detection of aneurysms <4 mm was found to be low. Conclusion: Aneurysms can also be appreciated on conventional brain MRI, and vascular structures should be reviewed carefully while analyzing brain MRI.

Prediction of the Outcome of Cochlear Implantation in the Patients with Congenital Cytomegalovirus Infection based on Magnetic Resonance Imaging Characteristics

Journal of Clinical Medicine ◽

10.3390/jcm8020136 ◽

2019 ◽

Vol 8 (2) ◽

pp. 136

Author(s):

Jae Han ◽

Yun Bae ◽

Seul Song ◽

Jae-Jin Song ◽

Ja-Won Koo ◽

...

Keyword(s):

Magnetic Resonance ◽

Cochlear Implantation ◽

Brain Mri ◽

Control Group ◽

Resonance Imaging ◽

Mri Findings ◽

Congenital Cytomegalovirus ◽

Imaging Characteristics

The goal of this study was to elucidate radiologic biomarker that can predict the outcome of cochlear implantation (CI) in congenital cytomegalovirus (cCMV) related deafness. A retrospective survey of speech perception after CI and an evaluation of brain magnetic resonance imaging (MRI) findings were performed in 10 cochlear implantees with cCMV-related prelingual deafness. Specifically, a special attention was paid to the degree of white matter (WM) abnormality shown in brain MRI, which was used to divide our cohort into two groups: The mild and severe pathology groups. Age-matched prelingual deaf patients with idiopathic sensorineural hearing loss were selected as controls. Subjects in mild pathology groups showed higher a Category of Auditory Performance (CAP) score (5.2 ± 0.8) than those with severe pathologies (3.4 ± 1.5) (P = 0.041). Importantly, speech performance from subjects with mild pathology was comparable to that of the control group (mean CAP score of 5.2 ± 0.8 vs. 5.1 ± 1.2) (P = 0.898). Mild pathologies related to the limited WM lesion in MRI not accompanied by severe MRI pathologies, such as diffuse WM abnormality, myelination delay, ventriculomegaly, migration abnormality, and cerebellar hypoplasia, can be tolerated and do not adversely affect the CI outcome in cCMV deafness.

Functional Magnetic Resonance Imaging of Language Function in Children

Brain Impairment ◽

10.1375/brim.3.2.132 ◽

2002 ◽

Vol 3 (2) ◽

pp. 132-139 ◽

Author(s):

Dianne P. Anderson

Keyword(s):

Magnetic Resonance ◽

Functional Magnetic Resonance Imaging ◽

Case Studies ◽

Clinical Samples ◽

Language Function ◽

Functional Magnetic Resonance ◽

Resonance Imaging ◽

Normal Children ◽

Language Functions

AbstractFunctional magnetic resonance imaging (fMRI) has been recognised as a neuroimaging technique suitable for examination of higher cognitive function in children. It has been used to elucidate cognitive neural networks associated with various aspects of language function in several group and case studies of school-aged children. Language function has been lateralised and localised with fMRI in clinical samples, neurologically normal children and children with developmental language disorders. Issues of plasticity of language function during development and following injury have also been considered. Several paediatric case studies have also raised questions with respect to the interpretation of fMRI language activation. In spite of methodological challenges, fMRI has proved a useful technique for examination of the brain-behaviour relationship in developmental language functions. This paper reviews fMRI studies of language, including reading, in children.