scholarly journals A survey on pulmonary screening practices among otolaryngology-head & neck surgeons across Saudi Arabia in the post treatment surveillance of head and neck squamous cell carcinoma: Cross sectional study . (Preprint)

2020 ◽  
Author(s):  
Majed Alnefaie ◽  
Asalh Saeedi ◽  
Abdullah Alamri ◽  
Yousuf Alqurashi ◽  
Hani Marzouki ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Saudi Arabia ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Post Treatment ◽  
Neck Squamous Cell Carcinoma ◽  
Lung Screening

BACKGROUND In head and neck squamous cell carcinoma patients (HNSCC), post treatment surveillance for distant disease is mostly focusing on the lungs, as HNSCC distant metastasis occurs in this organ in 90% of the cases and a high rate of primary of the lungs can be expected due to field cancerization of the entire upper aero digestive tract. OBJECTIVE The survey aimed to evaluate the current beliefs and pulmonary screening practices among otolaryngology-head & neck surgeons across Saudi Arabia in the post treatment surveillance of head and neck squamous cell carcinoma. METHODS This is a nation-wide cross sectional survey was conducted among Head and Neck surgeon members of the Saudi Society of Otolaryngology. Data Collected During The Period From 1– 30 July , 2020. Predesigned questionnaire including all the relevant questions to fulfill the study objectives. Questions inquired about characteristics of routine lung screening during the post treatment follow-up of head and neck cancer. The questionnaire distributed on all head and neck surgeon of the Saudi Society of Otolaryngology, of Saudi Arabia. RESULTS As regards the methods of routine lung screening during the post treatment follow-up of head and neck cancer, our study found that the majority 40% 9 out of 22 participants used lung radiography followed by 31% 7 out of 22 participants used low dose CT and 27 % 6 out of 22 participants used PET/CT. Regarding to duration of lung screening in head and neck cancer during follow up in physician's practice, the majority 77 % 17 out of 22 participants reported 5 years, 13% 3 out of 22 participants 10 years and only 9 % 2 out of 22 participants performed lung screening lifelong. As regards frequency of lung screening; 77 % 17 out of 22 participants reported annually screening,18% 4 out of 22 participants half-yearly and 4% 1 out of 22 participants biennially. According to believed effectiveness of the screening procedures listed in question 1 in reducing lung cancer mortality during the follow-up of head and neck cancer; 6% 8 out of 22 participants believed to be very effective or somewhat effective, 18% 4 out of 22 participants don’t know and only 9% 2 out of 22believed that it was not effective. CONCLUSIONS The majority used lung radiography, low dose CT and PET/CT as a routine lung screening during the post treatment follow-up of head and neck cancer for mainly 5 years, 10 years and only small percent performed lung screening lifelong. lung screening was mostly annually or half-yearly. The screening believed to be very effective or somewhat effective.

Should age affect our treatment decisions for head and neck cancer?

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 5564-5564
Author(s):  
Estrella M. Carballido ◽  
Jon N Burton ◽  
Miguel Ricardo Pelayo ◽  
Judith C McCaffrey ◽  
Tapan Padhya ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Comprehensive Cancer Center ◽  
Significant Difference

5564 Background: Current opinion suggests elderly patients (pts) with head and neck cancer, those 65 or older, do not tolerate surgery, chemotherapy, or radiation as well as their younger counterparts. If this holds true, elderly pts may not be offered standard treatments to prevent assumed complications. Methods: A retrospective cohort study at our comprehensive cancer center was conducted of newly diagnosed pts with head and neck squamous cell carcinoma to explore differences in treatment-related complications between older and younger groups. We included data from the first 199 eligible pts (99 younger than 65 year old and 100 older than 65) evaluated between April 2009 and June 2010. Results: 79% of pts receiving treatment were male with a mean age of 54.9 and 71.6 years for the younger and older groups respectively. The older group had significantly more comorbidities (p < 0.001). The majority of older pts presented with oral cavity tumors (46%) while the oropharynx was the predominant site in the younger group (45%). 55% of younger and 49% of older pts presented with stage 4 disease across all sites. A total of 51 pts were p16 positive with no statistical differences between the groups. Surgery was the initial treatment for 57% of older pts (p < 0.008) while 46% of younger pts received concurrent chemotherapy and radiation as the primary treatment (p < 0.008). There was no statistically significant difference in surgical or radiation complications between the groups. Although most pts receiving chemotherapy experienced complications, older pts had slightly more (93% vs. 78%; p<0.031). The mean survival was 24.8 months with no statistical difference between groups. Significantly more pts in the older group, at last follow-up, were disease free (p < 0.012). Conclusions: The treatment of elderly pts with head and neck squamous cell carcinoma in our experience was congruent with that of younger pts. Elderly pts did not suffer more complications with surgery or radiation, however chemotherapy produced somewhat more complications in the elderly pts. Elderly pts did display less evidence of disease on follow-up. Age is always a consideration when treating individuals, but should not preclude the curative standard.

Follow-up strategies in head and neck cancer other than upper aerodigestive tract squamous cell carcinoma

2012 ◽  
Vol 270 (7) ◽  
pp. 1981-1989 ◽  
Author(s):  
Antoine Digonnet ◽  
Marc Hamoir ◽  
Guy Andry ◽  
Vincent Vander Poorten ◽  
Missak Haigentz ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract

scholarly journals Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study

2010 ◽  
Vol 21 (4) ◽  
pp. 567-575 ◽  
Author(s):  
Kimon Divaris ◽  
Andrew F. Olshan ◽  
Joanna Smith ◽  
Mary E. Bell ◽  
Mark C. Weissler ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Cancer Study

Sentinel node in head and neck cancer: Use of size criterion to upstage the no neck in head and neck squamous cell carcinoma

Head & Neck ◽  
2007 ◽  
Vol 29 (2) ◽  
pp. 95-103 ◽  
Author(s):  
Lee W. T. Alkureishi ◽  
Gary L. Ross ◽  
D. Gordon MacDonald ◽  
Taimur Shoaib ◽  
Harry Gray ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Sentinel Node ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Size Criterion

scholarly journals Evaluation of Patient-Reported Delays and Affordability-Related Barriers to Care in Head and Neck Cancer

OTO Open ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 2473974X2110653
Author(s):  
Nicholas R. Lenze ◽  
Jeannette T. Bensen ◽  
Laura Farnan ◽  
Siddharth Sheth ◽  
Jose P. Zevallos ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Barriers To Care ◽  
Neck Squamous Cell Carcinoma ◽  
Patient Reported ◽  
Barrier To Care

Objective To examine the prevalence and predictors of patient-reported barriers to care among survivors of head and neck squamous cell carcinoma and the association with health-related quality of life (HRQOL) outcomes. Study Design Retrospective cohort study. Setting Outpatient oncology clinic at an academic tertiary care center. Methods Data were obtained from the UNC Health Registry/Cancer Survivorship Cohort. Barriers to care included self-reported delays in care and inability to obtain needed care due to cost. HRQOL was measured with validated questionnaires: general (PROMIS) and cancer specific (FACT-GP). Results The sample included 202 patients with head and neck squamous cell carcinoma with a mean age of 59.6 years (SD, 10.0). Eighty-two percent were male and 87% were White. Sixty-two patients (31%) reported at least 1 barrier to care. Significant predictors of a barrier to care in unadjusted analysis included age ≤60 years ( P = .007), female sex ( P = .020), being unmarried ( P = .016), being uninsured ( P = .047), and Medicaid insurance ( P = .022). Patients reporting barriers to care had significantly worse physical and mental HRQOL on the PROMIS questionnaires ( P < .001 and P = .002, respectively) and lower cancer-specific HRQOL on the FACT-GP questionnaire ( P < .001), which persisted across physical, social, emotional, and functional domains. There was no difference in 5-year OS (75.3% vs 84.1%, P = .177) or 5-year CSS (81.6% vs 85.4%, P = .542) in patients with and without barriers to care. Conclusion Delay- and affordability-related barriers are common among survivors of head and neck cancer and appear to be associated with significantly worse HRQOL outcomes. Certain sociodemographic groups appear to be more at risk of patient-reported barriers to care.

Human papillomavirus detection in head and neck squamous cell carcinoma in Turkey.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e17538-e17538
Author(s):  
Yasemin Kemal ◽  
Ozgur Kemal ◽  
Mehmet Kefeli ◽  
Ayse Bel ◽  
Nilgun Sahin ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Cancer ◽  
Squamous Cell ◽  
Large Scale ◽  
Neck Squamous Cell Carcinoma ◽  
Smoking History ◽  
Cancer Tissue

e17538 Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer worldwide. In Turkey, 5538 new cases and 2340 deaths from head and neck cancer are estimated to occur every year. Tobacco and alcohol are the most important etiological risk factors but in the past three decads tobacco usage is decreased and Human Papilloma Virus (HPV) has changed HNSCC epidemiology. Many new reports suggests that almost 25% of all cases of HNSCC are related to HPV. But its prevelans shows a wide variation among different populations.Today in Turkey HPV positivity in HNSCC is currently not known and this retrospective study aimed to to evaluate the HPV infection in our HNSCC patients. Methods: We included 125 HNSCC patients diagnosed and treated in our hospital beween January 2010 and December 2016. Oral cavity, oropharyngeal, laryngeal and hypopharyngeal cancers were included. Nasopharyngeal and salivary gland cancers were exculuded. Head and neck cancer tissue samples fixed using 10% Neutral Buffered Formalin and embedded blocks were used. From an initial evaluation of 125 patients records 77 of the paients blocks could be adequate for the HPV testing. Detection and genotyping of HPV genotypes were done using a polymerase chain reaction (PCR) protocol. Results: PCR amplification was succesful in 61 of 77 patients. Among the 61 HNSCC patients only 3 patients were HPV positive(4.9 %). HPV 16 subtype was detected in one patient who was 70 years old male, stage III laryngeal cancer with a smoking history. The subtypes detected in other two patients were different from 16 and 18. One of these patients was 42 years old nonsmoker female stage IVa hypopharyngeal cancer and the other one was 56 years old smoker male with stage II oropharyngeal cancer. Conclusions: In Turkey, this is the first study that evaluated HPV positivity in HNSCC. Our results suggest a low prevelance of HPV in Turkish HNSCC patients; large scale population based studies are needed to confirm our findings.

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